Risk for the Development of Treatment-Related Acute Myelocytic Leukemia and Myelodysplastic Syndrome Among Patients with Breast Cancer: Review of the Literature and the National Surgical Adjuvant Breast and Bowel Project Experience

2003 ◽  
Vol 4 (4) ◽  
pp. 273-279 ◽  
Author(s):  
Roy E. Smith
Keyword(s):  
Breast Cancer ◽  
Myelodysplastic Syndrome ◽  
Acute Myelocytic Leukemia ◽  
Review Of The Literature ◽  
National Surgical Adjuvant Breast ◽  
Myelocytic Leukemia ◽  
Cancer Review ◽  
Bowel Project

Different mechanisms lead to a karyotypically identical t(20;21) in myelodysplastic syndrome and in acute myelocytic leukemia

2003 ◽  
Vol 140 (1) ◽  
pp. 13-17 ◽  
Author(s):  
Caterina Matteucci ◽  
Roberta La Starza ◽  
Barbara Crescenzi ◽  
Silvia Romoli ◽  
Alessandra Santoro ◽  
...  
Keyword(s):  
Myelodysplastic Syndrome ◽  
Acute Myelocytic Leukemia ◽  
Myelocytic Leukemia

scholarly journals The use of low-level light therapy in supportive care for patients with breast cancer: review of the literature

2016 ◽  
Vol 32 (1) ◽  
pp. 229-242 ◽  
Author(s):  
Jolien Robijns ◽  
Sandrine Censabella ◽  
Paul Bulens ◽  
Annelies Maes ◽  
Jeroen Mebis
Keyword(s):  
Breast Cancer ◽  
Supportive Care ◽  
Light Therapy ◽  
Review Of The Literature ◽  
Low Level Light Therapy ◽  
Low Level ◽  
Cancer Review

Breast cancer estrogen and progesterone receptor values: their distribution, degree of concordance, and relation to number of positive axillary nodes.

1983 ◽  
Vol 1 (6) ◽  
pp. 349-358 ◽  
Author(s):  
B Fisher ◽  
D L Wickerham ◽  
A Brown ◽  
C K Redmond
Keyword(s):  
Breast Cancer ◽  
Estrogen Receptor ◽  
Progesterone Receptor ◽  
The Other ◽  
Breast Cancers ◽  
Patient Age ◽  
National Surgical Adjuvant Breast ◽  
Axillary Nodes ◽  
Bowel Project ◽  
Estrogen And Progesterone Receptor

Increasing evidence indicates the importance of ascertaining the quantitative estrogen receptor (ER) and progesterone receptor (PR) content (in femtomoles per milligram cytosol protein) of primary breast cancers. Those values obtained from the tumors of 1,887 patients participating in National Surgical Adjuvant Breast and Bowel Project protocol B-09 have been analyzed to define (1) the distribution of tumor ER or PR according to patient age, (2) the distribution of tumor PR within a specific ER interval, and (3) the concordance of tumor ER and PR levels. The present findings indicate how predictive the knowledge of the amount of one receptor (e.g., ER) may be for estimating the amount of the other (PR), when the latter is unknown.

Lumpectomy and radiation therapy for the treatment of intraductal breast cancer: findings from National Surgical Adjuvant Breast and Bowel Project B-17.

1998 ◽  
Vol 16 (2) ◽  
pp. 441-452 ◽  
Author(s):  
B Fisher ◽  
J Dignam ◽  
N Wolmark ◽  
E Mamounas ◽  
J Costantino ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Radiation Therapy ◽  
Breast Cancer Incidence ◽  
Resected Specimen ◽  
Cumulative Probability ◽  
Event Free Survival ◽  
Free Survival ◽  
National Surgical Adjuvant Breast ◽  
Bowel Project

PURPOSE In 1993, findings from a National Surgical Adjuvant Breast and Bowel Project (NSABP) trial to evaluate the worth of radiation therapy after lumpectomy concluded that the combination was more beneficial than lumpectomy alone for localized intraductal carcinoma-in-situ (DCIS). This report extends those findings. PATIENTS AND METHODS Women (N = 818) with localized DCIS were randomly assigned to lumpectomy or lumpectomy plus radiation (50 Gy). Tissue was removed so that resected specimen margins were histologically tumor-free. Mean follow-up time was 90 months (range, 67 to 130). Size and method of tumor detection were determined by central clinical, mammographic, and pathologic assessment. Life-table estimates of event-free survival and survival, average annual rates of occurrence for specific events, relative risks for event-specific end points, and cumulative probability of specific events comprising event-free survival are presented. RESULTS The benefit of lumpectomy plus radiation was virtually unchanged between 5 and 8 years of follow-up and was due to a reduction in invasive and noninvasive ipsilateral breast tumors (IBTs). Incidence of locoregional and distant events remained similar in both treatment groups; deaths were only infrequently related to breast cancer. Incidence of noninvasive IBT was reduced from 13.4% to 8.2% (P = .007), and of invasive IBT, from 13.4% to 3.9% (P < .0001). All cohorts benefited from radiation regardless of clinical or mammographic tumor characteristics. CONCLUSION Through 8 years of follow-up, our findings continue to indicate that lumpectomy plus radiation is more beneficial than lumpectomy alone for women with localized, mammographically detected DCIS. When evaluated according to the mammographic characteristics of their DCIS, all groups benefited from radiation.

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