Rippled Depth Thresholds: Estimates Obtained by Discrimination From Rippled and Nonrippled Reference Signals

2019 ◽  
Vol 105 (6) ◽  
pp. 1198-1205
Author(s):  
Alexander Ya. Supin ◽  
Olga N. Milekhina ◽  
Dmitry I. Nechaev

The objective of the study was to better understand of contribution of excitation-pattern and temporal-processing mechanisms of frequency analysis to discrimination of complex-spectrum signals in various discrimination tasks. Using rippled-spectrum signals, the ripple depth thresholds were measured as functions of ripple density under conditions of rippled or non-rippled reference signals. With rippled reference signals, the ripple depth thresholds were as low as 0.11 at low ripple densities (2–3 cycles/oct) and rose to 1.0 at a ripple density of 8.9 cycles/oct. For non-rippled reference signals, ripple depth thresholds were nearly the same as for rippled reference signals at ripple densities of up to 7 cycles/oct; at ripple densities of 10 cycles/oct and higher, ripple depth thresholds rose slowly and reached 1.0 at a ripple density of 26 cycles/oct. The results hypothetically suggest contributions of the excitation-pattern processing and temporal-processing mechanisms of frequency analysis to discrimination of rippled signals. The excitation-pattern mechanism featured low depth thresholds at low ripple densities but could not function at ripple densities above 10 cycles/oct. The temporal-processing mechanism manifested at higher ripple densities and non-rippled reference stimuli.

2002 ◽  
Vol 26 (4) ◽  
pp. 147-151 ◽  
Author(s):  
D. C. Smith ◽  
D. Keating ◽  
S. Parks ◽  
A.L. Evans

2020 ◽  
Vol 19 (6) ◽  
pp. 1321-1327
Author(s):  
Ting Huang ◽  
Yunbin Jiang ◽  
Yanfei Zhang ◽  
Yutian Lei ◽  
Guihua Jiang

Processing, a key characteristic of traditional Chinese medicine (TCM), enhances the efficacy and safety of Chinese materia medica (CMM) in clinics. It plays an important role in TCM. Studies on processing mechanisms involved in CMM promote the development of TCM. However, most studies on the mechanisms used for processing CMM do not reflect the holistic theory of TCM because they are based only on analysis of some specific  chemical components and biochemical indices which do not support the TCM characteristics of network target and multicomponent therapeutics. Fortunately, the perspective of systems biology is consistent with the holistic theory of TCM. Metabolomics, a key tool in systems biology, has been widely used to investigate the processing mechanism of CMM for many years. In this work, current applications of metabolomics in elucidating  mechanisms used for processing of CMM were systematically reviewed and discussed in terms of changes in chemical components, toxicity and efficacy of CMM before and after processing. This work provides researchers a clear and concise reference on the current application of  metabolomics in investigation of mechanisms used in processing of CMM. Moreover, this work provides a guide on how to investigate the  mechanisms used in processing of CMM, based on metabolomics. Keywords: Chinese materia medica, Processing mechanism, Metabolomics, Holistic theory


2014 ◽  
Vol 2 (3) ◽  
pp. 325-338 ◽  
Author(s):  
Carlos Montemayor ◽  
Marc Wittmann

We propose a hierarchical, three-level analysis of the present, in terms of simultaneity of events, experienced presence, and an extended mental presence containing the narrative self. The literature on the philosophy, psychology and neuroscience of time consciousness does not precisely distinguish these varieties of presence: first, a functional moment of perception in the range of milliseconds defines what is simultaneous and successive. Below a certain threshold events are processed as co-temporal. Secondly, the experienced moment of two to three seconds is related to a temporal-processing mechanism enabling conscious experience of the present moment. Thirdly, the continuity of experience is formed by working memory in the range of multiple seconds leading to the sense of mental presence over time, generating a temporal platform for the narrative self. These varieties of presence help solve puzzles pertaining to duration and simultaneity.


2004 ◽  
Vol 115 (5) ◽  
pp. 2466-2466
Author(s):  
Mitchell Steinschneider ◽  
Yonatan I. Fishman ◽  
Igor O. Volkov ◽  
Matthew A. Howard

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