scholarly journals The efficacy of lamotrigine for atypical absence status epilepticus in a case of perioral myoclonia with absence

2016 ◽  
Vol 8 (1) ◽  
pp. 1-8
Author(s):  
Yusuke Takezawa ◽  
Yosuke Kakisaka ◽  
Keisuke Wakusawa ◽  
Mamiko Ishitobi ◽  
Naomi Hino-Fukuyo ◽  
...  
2017 ◽  
Vol 2017 ◽  
pp. 1-4
Author(s):  
Channaiah Srikanth Mysore ◽  
Najib Murr ◽  
Rana Zabad ◽  
John Bertoni

Objective. We are reporting two cases: a patient with steroid responsive encephalopathy associated with autoimmune thyroiditis (SREAT) and another patient with secondary progressive multiple sclerosis (SPMS), both presenting with altered mental status (AMS) and later diagnosed with nonconvulsive atypical absence status epilepticus (AS), with atypical EEG changes. Methods. A report of two cases. Results. A patient with history of SREAT and the other with SPMS had multiple admissions due to AMS. For both, EEG revealed the presence of a high voltage generalized sharply contoured theta activity. A diagnosis of NCSE with clinical features of AS was made based on both clinical and EEG features. There was significant clinical and electrographic improvement with administration of levetiracetam for both patients in addition to sodium valproate and Solumedrol for the SREAT patient. Both patients continued to be seizure free on follow-up few months later. Conclusions. This is a report of two cases of atypical AS, with atypical EEG, in patients with different neurological conditions. Prompt clinical and EEG recovery occurred following appropriate medical treatment. We think that this condition might be underreported and could significantly benefit from prompt treatment when appropriately diagnosed.


Author(s):  
Zoryana Lebedyn

Nonconvulsive epileptic seizures are major type of seizures of all patients with predominantly focal epilepsy. However, this problem is still insufficiently studied, the literature presents a few data on the diagnosis and treatment of nonconvulsive status epilepticus (NCSE). NCSE is a prolonged seizure, not accompanied by severe motor presentation. Such attacks occur much more often than previously thought. NCSE is divided into focal NCSE (complex partial status epilepticus), and generalized NCSE, often referred as absence status. The absence status divides into a typical absence status (presents with suppression of consciousness of various depths, myoclonic twitching of the eyelids, impoverishment of speech production and hallucinations), atypical absence status (presents with retardation of mental processes and eyelid myoclonus) and late absence status (long-term disorientation accompanied by cognitive deficiency and presents mainly in elderly patients). According to the available sources, more than 30% of patients in the intensive care units with impaired consciousness of unclear genesis are patients with NCSE. Use of antiepileptic drugs for intravenous administration opens better opportunities in the treatment of patients with status epilepticus and NCSE.


2009 ◽  
Vol 92 (6) ◽  
pp. 472-477 ◽  
Author(s):  
T. Kudo ◽  
K. Sato ◽  
K. Yagi ◽  
M. Seino

Epilepsia ◽  
2004 ◽  
Vol 45 (10) ◽  
pp. 1240-1247 ◽  
Author(s):  
Jeffrey R. Tenney ◽  
Paul C. Marshall ◽  
Jean A. King ◽  
Craig F. Ferris

2018 ◽  
Vol 20 (6) ◽  
pp. 502-507 ◽  
Author(s):  
Roberto H. Caraballo ◽  
Santiago Chacón ◽  
Lorena Fasulo ◽  
Claudio Bedoya

1988 ◽  
Vol 24 (4) ◽  
pp. 582-584 ◽  
Author(s):  
Tahir Obeid ◽  
Basim Yaqub ◽  
Chrysostomos Panayiotopoulos ◽  
Saleh Al-Jasser ◽  
Azzam Shabaan ◽  
...  

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