scholarly journals Antiproliferative activity of selected medicinal plants of Jordan against a breast adenocarcinoma cell line (MCF7)

2007 ◽  
Vol 75 (3) ◽  
pp. 121-136 ◽  
Author(s):  
Rana Abu-Dahab
Keyword(s):  
Medicinal Plants ◽  
Cell Line ◽  
Antiproliferative Activity ◽  
Breast Adenocarcinoma ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell

Antiproliferative activity of Thai medicinal plant extracts on human breast adenocarcinoma cell line

Fitoterapia ◽  
2004 ◽  
Vol 75 (3-4) ◽  
pp. 375-377 ◽  
Author(s):  
Primchanien Moongkarndi ◽  
Nuttavut Kosem ◽  
Omboon Luanratana ◽  
Suna Jongsomboonkusol ◽  
Narongchai Pongpan
Keyword(s):  
Medicinal Plant ◽  
Cell Line ◽  
Plant Extracts ◽  
Antiproliferative Activity ◽  
Breast Adenocarcinoma ◽  
Human Breast ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Human Breast Adenocarcinoma ◽  
Medicinal Plant Extracts

scholarly journals Chemical Profiling, Antioxidant, Antiproliferative, and Antibacterial Potentials of Chemically Characterized Extract of Citrullus colocynthis L. Seeds

Separations ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 114
Author(s):  
Mohammed Bourhia ◽  
Kaoutar Bouothmany ◽  
Hanane Bakrim ◽  
Safa Hadrach ◽  
Ahmad Mohammad Salamatullah ◽  
...  
Keyword(s):  
Chemical Composition ◽  
Cell Line ◽  
Antiproliferative Activity ◽  
Seed Extract ◽  
Diffusion Method ◽  
Citrullus Colocynthis ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Ht 29 ◽  
Β Carotene

Background: Citrullus colocynthis L. (C. colocynthis) is commonly known as colocynth. It belongs to the family Cucurbitaceae that is frequently used in alternative medicine in the north of Africa. The aim of the study: the present research was undertaken to investigate the chemical composition, antioxidant, antiproliferative, and antibacterial potentials of C. colocynthis seed extract. Material and methods: the chemical composition of C. colocynthis seed organic extract was characterized using gas chromatography/mass spectrometry (GC-MS). The antioxidant property was carried out using both β-carotene bleaching and DPPH assays. The antibacterial effect was effectuated using the agar disc diffusion method. The antiproliferative activity vs. human colorectal adenocarcinoma cell line (HT-29) and human breast adenocarcinoma cell line (MDA MB 231) were carried by WST-1 test. The chemical analysis showed the presence of interesting potentially bioactive compounds. The studied plant extract exhibited antioxidant potential with IC50 value of 2. 22 mg/mL (β-carotene bleaching) and 8.98 ± 0.619 mg/mL (DPPH). Concerning the antiproliferative activity, the seed extract was effective in MDA-MB-231 and HT-29 cancer cells with IC50 values 86.89 ± 3.395 and 242.1 ± 17.9 μg/mL, respectively, whilst the extract of Citrullus colocynthis seeds was non-toxic in healthy human dermal fibroblasts. Regarding the antibacterial test, the extract was effective in Gram-positive bacteria only. Conclusion: The outcome of this research indicated that the extracts from C. colocynthis seeds may compose a promising source with interesting compounds that can be used to fight cancer, free radicals damage, and bacterial infections.

1,2-Dihydrochromeno[2,3-c]pyrrol-3-one Derivatives: Synthesis and HPLC-ECD Analysis

Synlett ◽  
2019 ◽  
Vol 30 (07) ◽  
pp. 799-802 ◽  
Author(s):  
László Tóth ◽  
Attila Kiss-Szikszai ◽  
Gábor Vasvári ◽  
Ferenc Fenyvesi ◽  
Miklós Vecsernyés ◽  
...  
Keyword(s):  
Double Bond ◽  
Cell Line ◽  
Antiproliferative Activity ◽  
Reductive Amination ◽  
Colorectal Adenocarcinoma ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Configurational Assignment ◽  
Stereogenic Center

Ethyl-3-formyl-6-methoxy-(2H)-chromene-2-carboxylate was transformed to N-substituted 1,2-dihydrochromeno[2,3-c]pyrrol-3-ones in a domino reductive amination–lactamization reaction. Isomerization of the double bond and the inherently labile stereogenic center was studied, and HPLC-ECD analysis of a chiral 1,2-dihydrochromeno[2,3-c]pyrrol-3(3aH)-one derivative aided by TDDFT-ECD calculation allowed configurational assignment of the separated enantiomers. Antiproliferative activity of the products was demonstrated on the CaCo-2 human epithelial colorectal adenocarcinoma cell line.

Therapeutic effects of bach1 siRNA on human breast adenocarcinoma cell line

2017 ◽  
Vol 88 ◽  
pp. 34-42 ◽  
Author(s):  
Mansoor Aletaha ◽  
Behzad Mansoori ◽  
Ali Mohammadi ◽  
Mehdi Fazeli ◽  
Behzad Baradaran
Keyword(s):  
Cell Line ◽  
Breast Adenocarcinoma ◽  
Therapeutic Effects ◽  
Human Breast ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Human Breast Adenocarcinoma

Glargine Promotes Proliferation of Breast Adenocarcinoma Cell Line MCF-7 via AKT Activation

2011 ◽  
Vol 43 (08) ◽  
pp. 519-523 ◽  
Author(s):  
J.-A. Teng ◽  
R.-L. Hou ◽  
D.-L. Li ◽  
R.-P. Yang ◽  
J. Qin
Keyword(s):  
Cell Line ◽  
Breast Adenocarcinoma ◽  
Adenocarcinoma Cell Line ◽  
Adenocarcinoma Cell ◽  
Akt Activation ◽  
Mcf 7
Sign in / Sign up

Export Citation Format

Share Document