scholarly journals Pathological Role of D-amino Acid-Containing Proteins and Advanced Glycation End Products in the Development of Age-Related Macular Degeneration

2010 ◽  
Vol 7 (10) ◽  
pp. 107-111 ◽  
Author(s):  
Yuichi Kaji ◽  
Tetsuro Oshika ◽  
Yutaka Takazawa ◽  
Masashi Fukayama ◽  
Noriko Fujii
Keyword(s):  
Amino Acid ◽  
Macular Degeneration ◽  
Advanced Glycation End Products ◽  
Age Related Macular Degeneration ◽  
Advanced Glycation ◽  
Age Related ◽  
Glycation End Products ◽  
End Products

Receptor for Advanced Glycation End Products and Age-Related Macular Degeneration

2004 ◽  
Vol 45 (10) ◽  
pp. 3713 ◽  
Author(s):  
Kimberly A. Howes ◽  
Yang Liu ◽  
Joshua L. Dunaief ◽  
Ann Milam ◽  
Jeanne M. Frederick ◽  
...  
Keyword(s):  
Macular Degeneration ◽  
Advanced Glycation End Products ◽  
Age Related Macular Degeneration ◽  
Advanced Glycation ◽  
Age Related ◽  
Glycation End Products ◽  
End Products

scholarly journals Role of Advanced Glycation End Products in Carcinogenesis and their Therapeutic Implications

2019 ◽  
Vol 24 (44) ◽  
pp. 5245-5251 ◽  
Author(s):  
David Schröter ◽  
Annika Höhn
Keyword(s):  
Advanced Glycation End Products ◽  
Molecular Mechanisms ◽  
The Body ◽  
Advanced Glycation ◽  
Therapeutic Implications ◽  
Age Related ◽  
Glycation End Products ◽  
End Products ◽  
Reduction Strategies

Aging is one of the biggest risk factors for the major prevalent diseases such as cardiovascular diseases, neurodegeneration and cancer, but due to the complex and multifactorial nature of the aging process, the molecular mechanisms underlying age-related diseases are not yet fully understood. Research has been intensive in the last years aiming to characterize the pathophysiology of aging and develop therapies to fight age-related diseases. In this context advanced glycation end products (AGEs) have received attention. AGEs, when accumulated in tissues, significantly increase the level of inflammation in the body which has long been associated with the development of cancer. Here we discuss the classical settings promoting AGE formation, as well as reduction strategies, occurrence and relevance of AGEs in cancer tissues and the role of AGE-interaction with the receptor for advanced glycation end products (RAGE) in cancer initiation and progression.

scholarly journals Role of advanced glycation end products in cellular signaling

Redox Biology ◽  
2014 ◽  
Vol 2 ◽  
pp. 411-429 ◽  
Author(s):  
Christiane Ott ◽  
Kathleen Jacobs ◽  
Elisa Haucke ◽  
Anne Navarrete Santos ◽  
Tilman Grune ◽  
...  
Keyword(s):  
Advanced Glycation End Products ◽  
Cellular Signaling ◽  
Advanced Glycation ◽  
Glycation End Products ◽  
End Products
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