Process Optimization using High Throughput Automated Micro-Bioreactors in Chinese Hamster Ovary Cell Cultivation

Journal of Visualized Experiments ◽

10.3791/60577 ◽

2020 ◽

Author(s):

Tamanna Nagraik ◽

Alina Gonzalez Salcedo ◽

Dörte Solle ◽

Thomas Scheper

Keyword(s):

Process Optimization ◽

Chinese Hamster Ovary Cell ◽

High Throughput ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell ◽

Cell Cultivation

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Interaction of leachable model compounds and their impact on Chinese hamster ovary cell cultivation

Biotechnology Progress ◽

10.1002/btpr.3150 ◽

2021 ◽

Author(s):

Dana Budde ◽

Gian‐Luca Albano ◽

Thomas Noll ◽

Elke Jurkiewicz

Keyword(s):

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell ◽

Cell Cultivation ◽

Model Compounds

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Temperature shift as a process optimization step for the production of pro-urokinase by a recombinant Chinese hamster ovary cell line in high-density perfusion culture

Journal of Bioscience and Bioengineering ◽

10.1016/s1389-1723(04)70198-x ◽

2004 ◽

Vol 97 (4) ◽

pp. 239-243 ◽

Cited By ~ 33

Author(s):

Zhao-Lie Chen ◽

Ben-Chuan Wu ◽

Hong Liu ◽

Xing-Mao Liu ◽

Pei-Tang Huang

Keyword(s):

Cell Line ◽

Process Optimization ◽

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Perfusion Culture ◽

Temperature Shift ◽

High Density ◽

Ovary Cell ◽

Ovary Cell Line

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Characterization of cyclic AMP-resistant Chinese hamster ovary cell mutants lacking type I protein kinase.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)70068-4 ◽

1981 ◽

Vol 256 (2) ◽

pp. 926-932 ◽

Cited By ~ 2

Author(s):

T.J. Singh ◽

C. Roth ◽

M.M. Gottesman ◽

I.H. Pastan

Keyword(s):

Protein Kinase ◽

Cyclic Amp ◽

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell ◽

Type I

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Isolation and characterization of a Chinese hamster ovary cell mutant with altered regulation of phosphatidylserine biosynthesis

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)47193-7 ◽

1989 ◽

Vol 264 (33) ◽

pp. 19887-19892

Author(s):

K Hasegawa ◽

O Kuge ◽

M Nishijima ◽

Y Akamatsu

Keyword(s):

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell ◽

Cell Mutant ◽

Isolation And Characterization ◽

Altered Regulation

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Characterization of Chinese hamster ovary cell lines expressing human steroid 5 alpha-reductase isozymes

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)85349-8 ◽

1993 ◽

Vol 268 (23) ◽

pp. 17404-17412

Author(s):

A.E. Thigpen ◽

K.M. Cala ◽

D.W. Russell

Keyword(s):

Cell Lines ◽

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell

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Alteration of the membrane lipid composition and infectivity of vesicular stomatitis virus by growth in a Chinese hamster ovary cell sterol mutant and in lipid-supplemented baby hamster kidney clone 21 cells.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(19)43884-2 ◽

1980 ◽

Vol 255 (16) ◽

pp. 7688-7693

Author(s):

R. Pal ◽

W.A. Petri ◽

R.R. Wagner

Keyword(s):

Chinese Hamster Ovary Cell ◽

Vesicular Stomatitis Virus ◽

Lipid Composition ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Membrane Lipid ◽

Ovary Cell ◽

Baby Hamster Kidney ◽

Membrane Lipid Composition ◽

Vesicular Stomatitis

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Structural studies of the major high mannose oligosaccharide units from Chinese hamster ovary cell glycoproteins.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)37814-6 ◽

1979 ◽

Vol 254 (5) ◽

pp. 1600-1605 ◽

Cited By ~ 26

Author(s):

E. Li ◽

S. Kornfeld

Keyword(s):

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell ◽

Structural Studies ◽

High Mannose

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Lec1A Chinese hamster ovary cell mutants appear to arise from a structural alteration in N-acetylglucosaminyltransferase I.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)67420-4 ◽

1986 ◽

Vol 261 (23) ◽

pp. 10551-10557

Author(s):

W Chaney ◽

P Stanley

Keyword(s):

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Structural Alteration ◽

Ovary Cell

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Chinese hamster ovary cell mutants defective in myo-inositol transport.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)44718-1 ◽

1990 ◽

Vol 265 (30) ◽

pp. 18083-18086

Author(s):

Y Ohga ◽

M Nishijima ◽

Y Akamatsu

Keyword(s):

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell

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Mitochondrial dysfunction of a cultured Chinese hamster ovary cell mutant deficient in cardiolipin.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(18)41613-4 ◽

1993 ◽

Vol 268 (30) ◽

pp. 22914-22919

Author(s):

T Ohtsuka ◽

M Nishijima ◽

K Suzuki ◽

Y Akamatsu

Keyword(s):

Mitochondrial Dysfunction ◽

Chinese Hamster Ovary Cell ◽

Chinese Hamster Ovary ◽

Chinese Hamster ◽

Ovary Cell ◽

Cell Mutant

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