Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice

10.3791/59310 ◽  
2019 ◽  
Author(s):  
Yunan Chen ◽  
Ming Li ◽  
Ying Zheng ◽  
Li Yang
Keyword(s):  
Motor Cortex ◽  
Local Field ◽  
Local Field Potential ◽  
Field Potential ◽  
Potential Recording ◽  
Field Potential Recording

Exploiting the directional local field potential recording capability of a new DBS lead for functional targeting in Parkinson’s disease

2015 ◽  
Vol 8 (2) ◽  
pp. 380
Author(s):  
M.A.J. Lourens ◽  
M.F. Contarino ◽  
R. Verhagen ◽  
P. van den Munckhof ◽  
P.R. Schuurman ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Local Field ◽  
Local Field Potential ◽  
Field Potential ◽  
Potential Recording ◽  
Field Potential Recording

scholarly journals Active C4 Electrodes for Local Field Potential Recording Applications

Sensors ◽  
2016 ◽  
Vol 16 (2) ◽  
pp. 198 ◽  
Author(s):  
Lu Wang ◽  
David Freedman ◽  
Mesut Sahin ◽  
M. Ünlü ◽  
Ronald Knepper
Keyword(s):  
Local Field ◽  
Local Field Potential ◽  
Field Potential ◽  
Potential Recording ◽  
Field Potential Recording

scholarly journals Learning Task-Related Activities From Independent Local-Field-Potential Components Across Motor Cortex Layers

2018 ◽  
Vol 12 ◽  
Author(s):  
Gonzalo Martín-Vázquez ◽  
Toshitake Asabuki ◽  
Yoshikazu Isomura ◽  
Tomoki Fukai
Keyword(s):  
Motor Cortex ◽  
Local Field ◽  
Local Field Potential ◽  
Field Potential ◽  
Learning Task

scholarly journals Chronic Stability of Single-Channel Neurophysiological Correlates of Gross and Fine Reaching Movements in the Rat

2019 ◽  
Author(s):  
David T. Bundy ◽  
David J Guggenmos ◽  
Maxwell D Murphy ◽  
Randolph J. Nudo
Keyword(s):  
Motor Cortex ◽  
Local Field ◽  
Neural Activity ◽  
Local Field Potential ◽  
Primary Motor Cortex ◽  
Spectral Power ◽  
Premotor Cortex ◽  
Field Potential ◽  
Motor Recovery ◽  
Reaching Movements

AbstractFollowing injury to motor cortex, reorganization occurs throughout spared brain regions and is thought to underlie motor recovery. Unfortunately, the standard neurophysiological and neuroanatomical measures of post-lesion plasticity are only indirectly related to observed changes in motor execution. While substantial task-related neural activity has been observed during motor tasks in rodent primary motor cortex and premotor cortex, the long-term stability of these responses in healthy rats is uncertain, limiting the interpretability of longitudinal changes in the specific patterns of neural activity during motor recovery following injury. This study examined the stability of task-related neural activity associated with execution of reaching movements in healthy rodents. Rats were trained to perform a novel reaching task combining a ‘gross’ lever press and a ‘fine’ pellet retrieval. In each animal, two chronic microelectrode arrays were implanted in motor cortex spanning the caudal forelimb area (rodent primary motor cortex) and the rostral forelimb area (rodent premotor cortex). We recorded multiunit spiking and local field potential activity from 10 days to 7-10 weeks post-implantation to characterize the patterns of neural activity observed during each task component and analyzed the consistency of channel-specific task-related neural activity. Task-related changes in neural activity were observed on the majority of channels. While the task-related changes in multi-unit spiking and local field potential spectral power were consistent over several weeks, spectral power changes were more stable, despite the trade-off of decreased spatial and temporal resolution. These results show that rodent primary and premotor cortex are both involved in reaching movements with stable patterns of task-related activity across time, establishing the relevance of the rodent for future studies designed to examine changes in task-related neural activity during recovery from focal cortical lesions.

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