scholarly journals Assembly and Characterization of Biomolecular Memristors Consisting of Ion Channel-doped Lipid Membranes

10.3791/58998 ◽  
2019 ◽  
Author(s):  
Joseph S. Najem ◽  
Graham J. Taylor ◽  
Nick Armendarez ◽  
Ryan J. Weiss ◽  
Md Sakib Hasan ◽  
...  
Keyword(s):  
Ion Channel ◽  
Lipid Membranes

scholarly journals Electrochemical Properties of Lipid Membranes Self-Assembled from Bicelles

Membranes ◽  
2020 ◽  
Vol 11 (1) ◽  
pp. 11
Author(s):  
Damian Dziubak ◽  
Kamil Strzelak ◽  
Slawomir Sek
Keyword(s):  
Electrochemical Properties ◽  
Self Assembly ◽  
Lipid Membranes ◽  
Lipid Membrane ◽  
Membrane Resistance ◽  
Electrochemical Characteristics ◽  
Freeze Thaw ◽  
Lipid Films ◽  
Supported Lipid Membranes

Supported lipid membranes are widely used platforms which serve as simplified models of cell membranes. Among numerous methods used for preparation of planar lipid films, self-assembly of bicelles appears to be promising strategy. Therefore, in this paper we have examined the mechanism of formation and the electrochemical properties of lipid films deposited onto thioglucose-modified gold electrodes from bicellar mixtures. It was found that adsorption of the bicelles occurs by replacement of interfacial water and it leads to formation of a double bilayer structure on the electrode surface. The resulting lipid assembly contains numerous defects and pinholes which affect the permeability of the membrane for ions and water. Significant improvement in morphology and electrochemical characteristics is achieved upon freeze–thaw treatment of the deposited membrane. The lipid assembly is rearranged to single bilayer configuration with locally occurring patches of the second bilayer, and the number of pinholes is substantially decreased. Electrochemical characterization of the lipid membrane after freeze–thaw treatment demonstrated that its permeability for ions and water is significantly reduced, which was manifested by the relatively high value of the membrane resistance.

Membrane supported bilayer lipid membranes array: preparation, stability and ion-channel insertion

2002 ◽  
Vol 460 (1) ◽  
pp. 23-34 ◽  
Author(s):  
G Favero ◽  
A D’Annibale ◽  
L Campanella ◽  
R Santucci ◽  
T Ferri
Keyword(s):  
Ion Channel ◽  
Lipid Membranes ◽  
Bilayer Lipid Membranes ◽  
Bilayer Lipid ◽  
Supported Bilayer

scholarly journals Biochemical and Functional Characterization of a Novel Prokaryote Ligand-Gated Ion Channel CLIC

2014 ◽  
Vol 106 (2) ◽  
pp. 545a
Author(s):  
Mieke Nys ◽  
Radovan Spurny ◽  
Zander Claes ◽  
Chris Ulens
Keyword(s):  
Ion Channel ◽  
Functional Characterization

scholarly journals Characterization of a 22-residue peptide derived from a designed ion channel

1997 ◽  
Vol 1328 (2) ◽  
pp. 177-184 ◽  
Author(s):  
Subhendu Seth ◽  
P Balaram ◽  
M.K Mathew
Keyword(s):  
Ion Channel
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