scholarly journals Frequency Mixing Magnetic Detection Scanner for Imaging Magnetic Particles in Planar Samples

10.3791/53869 ◽  
2016 ◽  
Author(s):  
Hyobong Hong ◽  
Eul-Gyoon Lim ◽  
Jae-chan Jeong ◽  
Jiho Chang ◽  
Sung-Woong Shin ◽  
...  
Keyword(s):  
Magnetic Particles ◽  
Magnetic Detection ◽  
Frequency Mixing

Magnetic immunoassay based on frequency mixing magnetic detection and magnetic particles of different magnetic properties

2014 ◽  
Vol 6 (19) ◽  
pp. 8055-8058 ◽  
Author(s):  
H. B. Hong ◽  
H.-J. Krause ◽  
I. H. Nam ◽  
C. J. Choi ◽  
S. W. Shin
Keyword(s):  
Magnetic Properties ◽  
Magnetic Particles ◽  
Different Types ◽  
Magnetic Detection ◽  
Analytical System ◽  
Frequency Mixing

A novel analytical system is presented that employs two different types of magnetic particles (MPs) with frequency mixing magnetic detection (FMMD).

Magnetic particle imaging with a planar frequency mixing magnetic detection scanner

2014 ◽  
Vol 85 (1) ◽  
pp. 013705 ◽  
Author(s):  
Hyobong Hong ◽  
Jaeho Lim ◽  
Chel-Jong Choi ◽  
Sung-Woong Shin ◽  
Hans-Joachim Krause
Keyword(s):  
Magnetic Particle ◽  
Magnetic Particle Imaging ◽  
Magnetic Detection ◽  
Particle Imaging ◽  
Frequency Mixing

scholarly journals Magnetic Particle Imaging Using Moving Halbach Cuboid and Frequency Mixing Magnetic Detection

2020 ◽  
Author(s):  
Jaechan Jeong ◽  
Jinsun Kim ◽  
Beomsu Seo ◽  
Hans Krause ◽  
Hyobong Hong
Keyword(s):  
Magnetic Particle ◽  
Permanent Magnets ◽  
Superparamagnetic Iron Oxide ◽  
Sample Volume ◽  
Excitation Field ◽  
Magnetic Particle Imaging ◽  
Magnetic Detection ◽  
Particle Imaging ◽  
Inverse Radon ◽  
Frequency Mixing

Abstract We present a magnetic particle imaging (MPI) device using a Halbach cuboid magnet and frequency mixing magnetic detection (FMMD) technology. A Field Free Line was formed in the center of a two-piece Halbach cuboid. Then, the cuboid was moved in the sample volume in a T-shaped and circular shape. The sample was exposed to a magnetic excitation field of two different frequencies. Due to the nonlinearity of the superparamagnetic iron oxide nanoparticles (SPIONs), harmonic frequencies and intermodulation products of the excitation frequencies are generated. This characteristic response signal from the particles was acquired by a coil system and demodulated by a FMMD electronics. Images were created by a backprojection method based on Radon and inverse Radon transformation. Using the Halbach cuboid, we were able to generate a stronger magnetic field compared to the previously reported equipment using large permanent magnets.. The results of the experiment showed that the combination of the Halbach cuboid and FMMD can acquire images similar to those of other existing MPI systems, suggesting that it is a method that has advantages in manufacturing and operation of MPI.

scholarly journals Multiplex Detection of Magnetic Beads Using Offset Field Dependent Frequency Mixing Magnetic Detection

Sensors ◽  
2021 ◽  
Vol 21 (17) ◽  
pp. 5859
Author(s):  
Ali Mohammad Pourshahidi ◽  
Stefan Achtsnicht ◽  
Mrinal Murali Nambipareechee ◽  
Andreas Offenhäusser ◽  
Hans-Joachim Krause
Keyword(s):  
Magnetic Beads ◽  
Programming Algorithm ◽  
Quantitative Detection ◽  
Multiplex Detection ◽  
Mixing Ratios ◽  
Field Dependent ◽  
Sample Amount ◽  
Magnetic Detection ◽  
Mixture Samples ◽  
Frequency Mixing

Magnetic immunoassays employing Frequency Mixing Magnetic Detection (FMMD) have recently become increasingly popular for quantitative detection of various analytes. Simultaneous analysis of a sample for two or more targets is desirable in order to reduce the sample amount, save consumables, and save time. We show that different types of magnetic beads can be distinguished according to their frequency mixing response to a two-frequency magnetic excitation at different static magnetic offset fields. We recorded the offset field dependent FMMD response of two different particle types at frequencies f1 + n⋅f2, n = 1, 2, 3, 4 with f1 = 30.8 kHz and f2 = 63 Hz. Their signals were clearly distinguishable by the locations of the extremes and zeros of their responses. Binary mixtures of the two particle types were prepared with different mixing ratios. The mixture samples were analyzed by determining the best linear combination of the two pure constituents that best resembled the measured signals of the mixtures. Using a quadratic programming algorithm, the mixing ratios could be determined with an accuracy of greater than 14%. If each particle type is functionalized with a different antibody, multiplex detection of two different analytes becomes feasible.

scholarly journals Magnetic Detection Structure for Lab-on-Chip Applications Based on the Frequency Mixing Technique

Sensors ◽  
2018 ◽  
Vol 18 (6) ◽  
pp. 1747 ◽  
Author(s):  
Amine Rabehi ◽  
Benjamin Garlan ◽  
Stefan Achtsnicht ◽  
Hans-Joachim Krause ◽  
Andreas Offenhäusser ◽  
...  
Keyword(s):  
Lab On Chip ◽  
Magnetic Detection ◽  
On Chip ◽  
Frequency Mixing

A magnetic super lattice

1987 ◽  
Vol 45 ◽  
pp. 360-361 ◽  
Author(s):  
M.D. Bentzon ◽  
J. v. Wonterghem ◽  
A. Thölén
Keyword(s):  
Thermal Decomposition ◽  
Oleic Acid ◽  
Magnetic Fluid ◽  
Magnetic Particles ◽  
Carbon Film ◽  
Thick Layer ◽  
Amorphous Iron ◽  
Super Lattice ◽  
Carrier Liquid ◽  
Median Diameter

We report on the oxidation of a magnetic fluid. The oxidation results in magnetic super lattice crystals. The “atoms” are hematite (α-Fe2O3) particles with a diameter ø = 6.9 nm and they are covered with a 1-2 nm thick layer of surfactant molecules.Magnetic fluids are homogeneous suspensions of small magnetic particles in a carrier liquid. To prevent agglomeration, the particles are coated with surfactant molecules. The magnetic fluid studied in this work was produced by thermal decomposition of Fe(CO)5 in Declin (carrier liquid) in the presence of oleic acid (surfactant). The magnetic particles consist of an amorphous iron-carbon alloy. For TEM investigation a droplet of the fluid was added to benzine and a carbon film on a copper net was immersed. When exposed to air the sample starts burning. The oxidation and electron irradiation transform the magnetic particles into hematite (α-Fe2O3) particles with a median diameter ø = 6.9 nm.

EFFECT OF APPLICATION OF FIELDS ON THE DOMAIN STRUCTURE IN SMALL REGULARLY SHAPED MAGNETIC PARTICLES

1988 ◽  
Vol 49 (C8) ◽  
pp. C8-1817-C8-1818 ◽  
Author(s):  
S. McVitie ◽  
J. N. Chapman ◽  
S. J. Hefferman ◽  
W. A. P. Nicholson
Keyword(s):  
Domain Structure ◽  
Magnetic Particles

Analysis of magneto rheological elastomers for energy harvesting systems

2020 ◽  
Vol 64 (1-4) ◽  
pp. 439-446
Author(s):  
Gildas Diguet ◽  
Gael Sebald ◽  
Masami Nakano ◽  
Mickaël Lallart ◽  
Jean-Yves Cavaillé
Keyword(s):  
Magnetic Field ◽  
Energy Harvesting ◽  
Shear Strain ◽  
Magnetic Induction ◽  
Magnetic Particles ◽  
Homogeneous Magnetic Field ◽  
Electrical Signal ◽  
Harvesting Systems ◽  
Dc Bias ◽  
Magneto Rheological

Magneto Rheological Elastomers (MREs) are composite materials based on an elastomer filled by magnetic particles. Anisotropic MRE can be easily manufactured by curing the material under homogeneous magnetic field which creates column of particles. The magnetic and elastic properties are actually coupled making these MREs suitable for energy conversion. From these remarkable properties, an energy harvesting device is considered through the application of a DC bias magnetic induction on two MREs as a metal piece is applying an AC shear strain on them. Such strain therefore changes the permeabilities of the elastomers, hence generating an AC magnetic induction which can be converted into AC electrical signal with the help of a coil. The device is simulated with a Finite Element Method software to examine the effect of the MRE parameters, the DC bias magnetic induction and applied shear strain (amplitude and frequency) on the resulting electrical signal.

Tuning the Magnetic Vortex State in Magnetite Nanodiscs for Remote Control of Biological Signalling

2019 ◽  
Author(s):  
Danijela Gregurec ◽  
Alexander W. Senko ◽  
Andrey Chuvilin ◽  
Pooja Reddy ◽  
Ashwin Sankararaman ◽  
...  
Keyword(s):  
Remote Control ◽  
Ion Channels ◽  
Ground State ◽  
Magnetic Particles ◽  
Colloidal Stability ◽  
Vortex State ◽  
Magnetic Vortex ◽  
Electron Holography ◽  
Dipole Interactions ◽  
Magnetite Particles

In this work, we demonstrate the application of anisotropic magnetite nanodiscs (MNDs) as transducers of torque to mechanosensory cells under weak, slowly varying magnetic fields (MFs). These MNDs possess a ground state vortex configuration of magnetic spins which affords greater colloidal stability due to eliminated dipole-dipole interactions characteristic of isotropic magnetic particles of similar size. We first predict vortex magnetization using micromagnetic stimulations in sub-micron anisotropic magnetite particles and then use electron holography to experimentally investigate the magnetization of MNDs 98–226 nm in diameter. When MNDs are coupled to MFs, they transition between vortex and in-plane magnetization allowing for the exertion of the torque on the pN scale, which is sufficient to activate mechanosensitive ion channels in cell membranes.<br>

Preparation and Properties of Arrays of Very Small Magnetic Particles.

1987 ◽  
Author(s):  
C. D. Graham ◽  
Kaatz Jr. ◽  
Forrest
Keyword(s):  
Magnetic Particles
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