scholarly journals The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

10.3791/50509 ◽  
2013 ◽  
Author(s):  
Rishu Gupta ◽  
Maya Debbaneh ◽  
Daniel Butler ◽  
Monica Huynh ◽  
Ethan Levin ◽  
...  
Keyword(s):  
Severe Psoriasis ◽  
Goeckerman Regimen

Ixekizumab in the Management of Non-Selected Out Patients with Moderate to Severe Psoriasis -New Data and Personal Clinical Experience

2018 ◽  
Vol 3 (3) ◽  
Keyword(s):  
Clinical Experience ◽  
Personal Experience ◽  
Therapeutic Response ◽  
Systemic Disease ◽  
Severe Psoriasis ◽  
Adequate Treatment ◽  
Scalp Psoriasis ◽  
Number Of Patients ◽  
Genital Psoriasis

Introduction: Too many patients with moderate to severe psoriasis do not receive adequate treatment. This means a vast undersupply in the treatment of patients with psoriasis. Only biologics fulfill the whole range of the treatment of psoriasis – psoriasis does not affect only skin but the whole organism: It is a systemic disease! Between the biologics are evident differences concerning the effect. Discussion: Based on broad personal experience in the management of patients with moderate to severe psoriasis new data from clinical studies with ixekizumab are examined. This contains new data on long-term-efficacy of ixekizumab, effectiveness in special localizations (scalp psoriasis, nail psoriasis, palmoplantar psoriasis, genital psoriasis) as well as safely data and experience on patients switched to ixekizumab from other biologics. Personal clinical experience is based on >300 non-selected outpatients with moderate to severe psoriasis, >250 patients on biological therapies, > 50 patients with ixekizumab. Conclusions: Focusing on a relevant number of patients switched from secukinumab to ixekizumab due to first or secondary loss of efficacy significant differences between both IL-17A-inhibitors mainly in terms of efficacy and speed of therapeutic response are shown. Finally the correlation between PASI-90-/PASI-100 response and significant changes in DLQI are highlighted.

Cyclosporin for severe psoriasis.

1991 ◽  
Vol 53 (2) ◽  
pp. 353-359
Author(s):  
Takashi HORIKOSHI ◽  
Hideo ONODERA ◽  
Kuniko KAWAMURA ◽  
Hiroaki EGUCHI ◽  
Makoto TAKAHASHI
Keyword(s):  
Severe Psoriasis
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