scholarly journals Morphological Analysis of Drosophila Larval Peripheral Sensory Neuron Dendrites and Axons Using Genetic Mosaics

10.3791/3111 ◽  
2011 ◽  
Author(s):  
M. Rezaul Karim ◽  
Adrian W. Moore
Keyword(s):  
Sensory Neuron ◽  
Morphological Analysis ◽  
Genetic Mosaics ◽  
Peripheral Sensory

scholarly journals Development and validation of an in vitro model system to study peripheral sensory neuron development and injury

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Iwan Jones ◽  
Tushar Devanand Yelhekar ◽  
Rebecca Wiberg ◽  
Paul J. Kingham ◽  
Staffan Johansson ◽  
...  
Keyword(s):  
Sensory Neuron ◽  
In Vitro Model ◽  
Model System ◽  
Neuron Development ◽  
In Vitro Model System ◽  
Vitro Model ◽  
Development And Validation ◽  
Peripheral Sensory

scholarly journals VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review

2013 ◽  
Vol 2013 ◽  
pp. 1-28 ◽  
Author(s):  
Pablo R. Brumovsky
Keyword(s):  
Spinal Cord ◽  
Synaptic Vesicles ◽  
Morphological Analysis ◽  
Current Knowledge ◽  
Historical Account ◽  
Peripheral Neurons ◽  
Physiological Relevance ◽  
Autonomic Neurons ◽  
Vesicular Glutamate Transporters ◽  
Peripheral Sensory

Vesicular glutamate transporters (VGLUTs) are key molecules for the incorporation of glutamate in synaptic vesicles across the nervous system, and since their discovery in the early 1990s, research on these transporters has been intense and productive. This review will focus on several aspects of VGLUTs research on neurons in the periphery and the spinal cord. Firstly, it will begin with a historical account on the evolution of the morphological analysis of glutamatergic systems and the pivotal role played by the discovery of VGLUTs. Secondly, and in order to provide an appropriate framework, there will be a synthetic description of the neuroanatomy and neurochemistry of peripheral neurons and the spinal cord. This will be followed by a succinct description of the current knowledge on the expression of VGLUTs in peripheral sensory and autonomic neurons and neurons in the spinal cord. Finally, this review will address the modulation of VGLUTs expression after nerve and tissue insult, their physiological relevance in relation to sensation, pain, and neuroprotection, and their potential pharmacological usefulness.

scholarly journals Transcriptional Reprogramming of Distinct Peripheral Sensory Neuron Subtypes after Axonal Injury

Neuron ◽  
2020 ◽  
Vol 108 (1) ◽  
pp. 128-144.e9 ◽  
Author(s):  
William Renthal ◽  
Ivan Tochitsky ◽  
Lite Yang ◽  
Yung-Chih Cheng ◽  
Emmy Li ◽  
...  
Keyword(s):  
Sensory Neuron ◽  
Axonal Injury ◽  
Transcriptional Reprogramming ◽  
Peripheral Sensory

scholarly journals Glial ensheathment of the somatodendritic compartment regulates sensory neuron structure and activity

2019 ◽  
Vol 116 (11) ◽  
pp. 5126-5134 ◽  
Author(s):  
Smita Yadav ◽  
Susan H. Younger ◽  
Linghua Zhang ◽  
Katherine L. Thompson-Peer ◽  
Tun Li ◽  
...  
Keyword(s):  
Sensory Neuron ◽  
Sensory Neurons ◽  
Cell Types ◽  
Environmental Cues ◽  
Sensory Stimuli ◽  
Neuronal Soma ◽  
Selective Elimination ◽  
Light Stimuli ◽  
Peripheral Sensory ◽  
Structure And Activity

Sensory neurons perceive environmental cues and are important of organismal survival. Peripheral sensory neurons interact intimately with glial cells. While the function of axonal ensheathment by glia is well studied, less is known about the functional significance of glial interaction with the somatodendritic compartment of neurons. Herein, we show that three distinct glia cell types differentially wrap around the axonal and somatodendritic surface of the polymodal dendritic arborization (da) neuron of the Drosophila peripheral nervous system for detection of thermal, mechanical, and light stimuli. We find that glial cell-specific loss of the chromatin modifier gene dATRX in the subperineurial glial layer leads to selective elimination of somatodendritic glial ensheathment, thus allowing us to investigate the function of such ensheathment. We find that somatodendritic glial ensheathment regulates the morphology of the dendritic arbor, as well as the activity of the sensory neuron, in response to sensory stimuli. Additionally, glial ensheathment of the neuronal soma influences dendritic regeneration after injury.

CGRP-immunoreactive cells supplying laryngeal sensory nerve fibres in the cat's nodose ganglion

1993 ◽  
Vol 107 (10) ◽  
pp. 916-919 ◽  
Author(s):  
Yasumusa Tanaka ◽  
Yoshikazu Yoshida ◽  
Minoru Hirano
Keyword(s):  
Sensory Neuron ◽  
Sensory Neurons ◽  
Sensory Nerve ◽  
Middle Part ◽  
Nodose Ganglion ◽  
Sensory Innervation ◽  
Sensory Cells ◽  
Laryngeal Mucosa ◽  
Peripheral Sensory ◽  
Rostral Part

AbstractThrough a combination of retrograde staining by wheat germ agglutinin (WGA) and immunohistochemistry, calcitonin gene-related peptide (CGRP)-reactive sensory neurons projecting from the laryngeal mucosa were detected in the feline nodose ganglion. The size of the CGRP-immunoreactive cell which was regarded as a laryngeal sensory neuron, was about 60 ±m in diameter: the shape of the immunoreactive laryngeal sensory neuron was unipolar. CGRP-reacted laryngeal sensory cells were found in the rostral part of the nodose ganglion extending to the middle part. They aggregated in the most rostral part, were sparse in other parts and were approximately 50 per cent of WGA-reactive laryngeal sensory neurons in number. Our results suggest that this neurotransmitter might play an important role in laryngeal peripheral sensory innervation.

Sign in / Sign up

Export Citation Format

Share Document