scholarly journals THE CORRELATION BETWEEN SERUM VITAMIN D LEVELS AND CUTANEOUS INVOLVEMENT IN METABOLIC SYNDROME

2017 ◽  
Vol 64 (4) ◽  
pp. 300-304
Author(s):  
Ana Maria Alexandra Stănescu ◽  
◽  
Ioana Veronica Grăjdeanu ◽  
Gabriel Cristian Bejan ◽  
Mihaela Adela Iancu ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Serum Vitamin ◽  
International Diabetes Federation ◽  
Hdl Cholesterol ◽  
Cutaneous Involvement ◽  
Serum Vitamin D ◽  
The Metabolic Syndrome ◽  
Vitamin D Levels ◽  
Metabolic Syndrome Components

Aims. The rising global trend of metabolic syndrome cases has increased the problems associated with decreasing serum vitamin D levels and the likelihood of cutaneous involvement. This research was aimed at determining the prevalence of metabolic syndrome, the distribution of its components and correlation the between serum vitamin D levels and possible skin involvement in the patients. Materials and methods. The study of Romanian citizens was conducted between 2010 and 2017, involved mainly urban dwellers with a median age of 18. The parameters measured included physical examination and fasting blood tests. The criteria of the International Diabetes Federation (IDF) was used for the metabolic syndrome diagnosis. The serum 25 (OH) D levels were based on the laboratory reference values and the severity of psoriasis was calculated according to the BSA score. Results. The total number of participants in the study was 634, of which 36% were diagnosed with metabolic syndrome, with a 59% prevalence of females. The distribution of the components of the metabolic syndrome was: 100% increased waist circumference (mandatory component for diagnosis), hyperglycaemia 53.7%, low HDL cholesterol 44.9%, triglyceride increase 26.4%, high blood pressure 21.6%. Low serum vitamin D levels were found at 54.6%. Psoriasis showed 46.2% of all those with metabolic syndrome. Conclusion. After thorough analysis of the data, it can be concluded that there is a relationship between the presence of metabolic syndrome and serum vitamin D, the latter being mostly low in the studied group. The more the components of metabolic syndrome are present, the lower the vitamin D serum level. The presence of psoriasis can aggravate metabolic syndrome components and vitamin D serum decline. Further studies can determine whether serum vitamin D normalization can bring improvements in metabolic syndrome components.

scholarly journals Relationship between Serum Vitamin D Levels and HDL Cholesterol in Postmenopausal Women from Colombian Caribbean

2018 ◽  
Vol 2018 ◽  
pp. 1-6 ◽  
Author(s):  
Luz Adriana Sarmiento-Rubiano ◽  
José Armando Angarita Ruidiaz ◽  
Héctor Fernando Suarez Dávila ◽  
Alfonso Suarez Rodríguez ◽  
Roberto C. Rebolledo-Cobos ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Postmenopausal Women ◽  
Serum Vitamin ◽  
Hdl Cholesterol ◽  
Serum Vitamin D ◽  
The Metabolic Syndrome ◽  
Increased Risk ◽  
Vitamin D Levels

Background. Previous evidence suggests that metabolic disorders in postmenopausal women could be related with low serum vitamin D levels. For example, vitamin D deficiency has been associated with increased risk factors for cardiovascular disease (CVD), mainly those related with metabolic syndrome.Objective. To assess the relationship between the serum vitamin D (25-OH-D) levels and the metabolic syndrome markers in postmenopausal women.Methods. This descriptive and cross-sectional study was conducted in 183 postmenopausal women of four municipalities from Colombian Caribbean. The serum 25-OH-D levels and the anthropometric and biochemical markers were assessed and correlated with metabolic syndrome.Results. The average value of serum vitamin D (25-OH-D) was 26.34 ± 9.08 ng/mL, and 69.95% of the women had vitamin D levels <30 ng/mL, of which 43.72% were with insufficiency (<30 to >20 ng/mL) and 26.23% with deficiency (<20 ng/mL). Of the evaluated women, the 81.42% seemed to have metabolic syndrome. Through the linear regression, one significant positive association was observed between the HDL cholesterol and the 25-OH-D levels (P=0.014).Conclusion. In the evaluated population in this study, vitamin D deficiency is related with low HDL cholesterol levels.

scholarly journals Serum Vitamin D Concentration Does Not Predict Insulin Action or Secretion in European Subjects With the Metabolic Syndrome

Diabetes Care ◽  
2010 ◽  
Vol 33 (4) ◽  
pp. 923-925 ◽  
Author(s):  
H. L. Gulseth ◽  
I. M. F. Gjelstad ◽  
A. C. Tierney ◽  
J. A. Lovegrove ◽  
C. Defoort ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Insulin Action ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
The Metabolic Syndrome

scholarly journals Concentrations of Serum Vitamin D and the Metabolic Syndrome Among U.S. Adults

Diabetes Care ◽  
2005 ◽  
Vol 28 (5) ◽  
pp. 1228-1230 ◽  
Author(s):  
E. S. Ford ◽  
U. A. Ajani ◽  
L. C. McGuire ◽  
S. Liu
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Serum Vitamin ◽  
Serum Vitamin D ◽  
The Metabolic Syndrome

scholarly journals Assessment of Relationship Between Serum Vitamin D Levels and Metabolic Syndrome Components in Hemodialysis Patients

2021 ◽  
Vol 28 (1) ◽  
pp. E202113
Author(s):  
Sevil Karahan Yılmaz ◽  
Cuma Mertoğlu ◽  
Aylin Ayaz
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Vitamin D Deficiency ◽  
Serum Vitamin ◽  
Vitamin D Insufficiency ◽  
Hemodialysis Patients ◽  
Hydroxyvitamin D ◽  
Serum Vitamin D ◽  
Vitamin D Levels ◽  
25 Oh Vitamin D

Aim: This study is aimed to evaluate the relationship between serum vitamin D levels and metabolic syndrome in hemodialysis patients. Materials and Methods: This study was conducted with participation of 80 patients undergoing hemodialysis for more than 6 months three times a week, aged > 18 years. Their height, dry weight, waist circumference were measured. Biochemical parameters such as serum 25-hydroxyvitamin D, lipid profile, and fasting blood glucose were analyzed. Metabolic syndrome was defined using the National Cholesterol Education Program Adult Treatment Panel III criteria. Severe vitamin D deficiency, 25 (OH) vitamin D < 5 ng/ml; mild vitamin D deficiency, 25 (OH) vitamin D 5-15 ng/ml; vitamin D insufficiency, 25 (OH) vitamin D 16-30 ng/ml, and vitamin D sufficiency, 25 (OH) vitamin D > 30 ng/ml were categorized. Statistical analysis of the data was performed with the use of SPSS version 21.0. Results: 48.4% of hemodialysis patients were identified to have metabolic syndrome. According to the serum levels of vitamin D; 35.0% of patients had severe vitamin D deficiency, 37.4% of patients had mild vitamin D deficiency, 18.8% of patients had vitamin D insufficiency and 8.8% of patients had vitamin D sufficiency (> 30 ng/ml). Vitamin D insufficiency was significantly associated with metabolic syndrome and central obesity. Conclusions: Deficiency/insufficiency is observed in serum 25-hydroxyvitamin D levels in hemodialysis patients. Vitamin D insufficiency is associated with metabolic syndrome.

scholarly journals Sunlight Has Cardiovascular Benefits Independently of Vitamin D

2016 ◽  
Vol 41 (1-3) ◽  
pp. 130-134 ◽  
Author(s):  
Richard B. Weller
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Risk Factor ◽  
Serum Vitamin ◽  
Sun Exposure ◽  
High Serum ◽  
Serum Vitamin D ◽  
Life Years ◽  
Vitamin D Levels ◽  
All Cause Mortality

Background: High blood pressure (BP) is the leading risk factor for disability adjusted life years lost globally. Epidemiological data show a correlation between increased sun exposure and reduced population BP and cardiovascular mortality. Individuals with high serum vitamin D levels are at reduced risk of hypertension, cardiovascular disease and metabolic syndrome, yet multiple trial data show that oral vitamin D supplementation has no effect on these endpoints. Sunlight is a risk factor for skin cancers, but no link has been shown with increased all-cause mortality. Cohort studies from Scandinavia show a dose-dependent fall in mortality with increased sun-seeking behaviour. Skin contains significant stores of nitrogen oxides, which can be converted to NO by UV radiation and exported to the systemic circulation. Human studies show that this pathway can cause arterial vasodilatation and reduced BP. Murine studies suggest the same mechanism may reduce metabolic syndrome. Summary: Sunlight has beneficial effects on cardiovascular risk factors independently of vitamin D. Key Messages: All-cause mortality should be the primary determinant of public health messages. Sunlight is a risk factor for skin cancer, but sun avoidance may carry more of a cost than benefit for overall good health.

scholarly journals High serum vitamin D levels reduce the risk for nonalcoholic fatty liver disease in healthy men independent of metabolic syndrome

2013 ◽  
Vol 60 (6) ◽  
pp. 743-752 ◽  
Author(s):  
Eun-Jung Rhee ◽  
Mee Kyoung Kim ◽  
Se Eun Park ◽  
Cheol-Young Park ◽  
Ki Hyun Baek ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Vitamin D ◽  
Liver Disease ◽  
Fatty Liver Disease ◽  
Serum Vitamin ◽  
High Serum ◽  
Nonalcoholic Fatty Liver ◽  
Healthy Men ◽  
Serum Vitamin D ◽  
Vitamin D Levels
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