scholarly journals EARLY PREDICTION OF PREECLAMPSIA ÎN PREGNANCY

2017 ◽  
Vol 64 (1) ◽  
pp. 34-37
Author(s):  
Oana Mihaela Iordache ◽  
◽  
Liliana Neştianu ◽  
George Erick Neştianu ◽  
◽  
...  

Preeclampsia is a major health problem because it determines higher incidence in maternal and perinatal morbidity. Early prediction of preeclampsia in pregnancy can improve both the maternal and perinatal outcome by ensuring appropriate management. There are multiple algorithms using maternal risk factors, biophysical markers, biochemical markers and they try to predict preeclampsia. Low doses of aspirin can improve the prognostic of preeclampsia.

PLoS ONE ◽  
2015 ◽  
Vol 10 (12) ◽  
pp. e0145873 ◽  
Author(s):  
Giuseppe Esposito ◽  
Rossella Ambrosio ◽  
Francesco Napolitano ◽  
Gabriella Di Giuseppe

Author(s):  
Kanchan Durugkar

Background: The HELLP syndrome is a serious complication in pregnancy characterized by haemolysis, elevated liver enzymes and low platelet count occurring in 0.5 to 0.9% of all pregnancies and in 10-20% of cases with severe preeclampsia. The objective of the present prospective study is to study on incidence, diagnosis, and variable presentations of HELLP syndrome in preeclampsia to analyse the severity and complications, as it is associated with maternal, perinatal morbidity and mortality. HELLP syndrome is difficult to diagnose when it presents with atypical clinical features.Methods: In the prospective study of 300 admitted cases with more than 20 weeks of gestation, were having preeclampsia. The selected cases were analyzed clinically with relevant history, clinical data and detailed laboratory investigations made for better analyses of complications and outcome in HELLP syndrome.Results: Under further clinical diagnosis of 300 cases of preeclampsia, 34 cases (11.33%) were of HELLP Syndrome and 44 (14.66%) cases were of partial HELLP syndrome. The present study shows 2.9% maternal mortality in HELLP and 4.5% in partial HELLP syndrome. Perinatal mortality was 17.6% with HELLP and 25% with partial HELLP.Conclusions: The diagnosis of HELLP syndrome has been made as a severe variant and complication of severe preeclampsia and eclampsia. It needs early diagnosis, timely intervention to arrest further progress and complications like multi organ dysfunction, renal failure, DIC, abruption etc and to improve maternal and perinatal outcome.


Proceedings ◽  
2019 ◽  
Vol 37 (1) ◽  
pp. 26
Author(s):  
Manerkar ◽  
Harding ◽  
Conlon ◽  
McKinlay

Gestational diabetes mellitus (GDM) is a major health problem not only in pregnancy but alsofor lifelong health, with increased risks of obesity and diabetes in offspring [...]


2011 ◽  
Vol 25 (4) ◽  
pp. 369-373 ◽  
Author(s):  
Eva Anne Marije Van Eerd ◽  
Alphonse Joseph M. Roex ◽  
Payam Nikpoor ◽  
Gustaaf A. Dekker

Author(s):  
Manish Agrawal ◽  
Kriti Bhatnagar

Background: India has made considerable progress over the last two decades in the area of maternal and child health, through innovative and comprehensive health packages that covers the spectrum of Reproductive Child Health (RCH). Awareness of the special vulnerability of the cohort of mothers with ‘high risk factor’ has led to the popular recognition of ‘risk approach’, involving the optimal use of existing MCH services, providing essential obstetrical care for all with early detection of complications and emergency services for those who need it, thus reducing the need for intensive care along with reduction in perinantal mortality. The objective was to assess the prevalence of various maternal risk factors in pregnant women in hospital admissions and their correlation with perinatal mortality.Methods: The present study was carried out on 2050 consecutive deliveries from 1st April 2015 to 31st March 2016 at Department of Obstetrics and Gynecology and Department of Pediatrics, Muzaffarnagar Medical College, Muzaffarnagar Uttar Pradesh, India. All the pregnant women were interviewed and examined in detail at the onset of labor regarding various biosocio-economic characteristics, history of past and present medical and obstetrical complications.Results: The PNMR (93.66/1000 birth) observed in present study was still at a higher level and comparable to that in other studies done by various authors in past in this region. A significantly higher PNMR was observed with increase in maternal age and parity (3 times higher PNMR at >35 years and 2 ½ times higher PNMR at parity >5). Similarly, medical illnesses (3 times higher PNMR) and obstetrical complications (1.5 times higher PNMR) during present pregnancy were showing significant effect on perinatal outcome. In a multivariate analysis, residence (rural /urban), place and number of antenatal visits, gestational age and type of delivery remained as most significant maternal risk factors (p<0.005) after multiple logistic regression of other factors viz. maternal age, height, weight, parity, education, socio-economic status and antepartum anemia.Conclusions: It is heartening to observe that highest risk is associated with simple and easily identifiable factors like, unbooked cases, <3 antenatal visits, severe anemia, age >35 years, parity >5, weight <40 kg, height < 140cm , poor dietary calories, medical and obstetrical complications. These can identified from history only by grass root workers like traditional birth attendants and even elderly female family members. These risk determinants, labeled as simple but ‘high’ high risk are associated with poor perinatal outcome. If these factors are timely identified at community level and appropriately referred by grass root workers, it will significantly reduce perinatal mortality and improve neonatal survival.


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