IN VITRO ANTI-DIABETIC AND ANTI-INFLAMMATORY PROPERTIES OF HERBAL DECOCTION FROM LEAVES OF COCCINIA INDICA, ORTHOSIPHON STAMINEUS AND CARDIOSPERMUM HALICACABUM

2021 ◽  
Vol 34 (02) ◽  
Author(s):  
S Tamilselvi ◽  
◽  
R Sathyaseela ◽  
Keyword(s):  
Orthosiphon Stamineus ◽  
Herbal Decoction ◽  
Coccinia Indica ◽  
Anti Inflammatory

An in vitro model for investigation of vitamin A effects on wound healing

2021 ◽  
pp. 1-6
Author(s):  
Hoda Keshmiri Neghab ◽  
Mohammad Hasan Soheilifar ◽  
Gholamreza Esmaeeli Djavid
Keyword(s):  
Wound Healing ◽  
Endothelial Cell ◽  
Vitamin A ◽  
In Vitro Model ◽  
Cellular Proliferation ◽  
Endothelial Cell Migration ◽  
Normal Fibroblast ◽  
Anti Inflammatory ◽  
Vitro Model

Abstract. Wound healing consists of a series of highly orderly overlapping processes characterized by hemostasis, inflammation, proliferation, and remodeling. Prolongation or interruption in each phase can lead to delayed wound healing or a non-healing chronic wound. Vitamin A is a crucial nutrient that is most beneficial for the health of the skin. The present study was undertaken to determine the effect of vitamin A on regeneration, angiogenesis, and inflammation characteristics in an in vitro model system during wound healing. For this purpose, mouse skin normal fibroblast (L929), human umbilical vein endothelial cell (HUVEC), and monocyte/macrophage-like cell line (RAW 264.7) were considered to evaluate proliferation, angiogenesis, and anti-inflammatory responses, respectively. Vitamin A (0.1–5 μM) increased cellular proliferation of L929 and HUVEC (p < 0.05). Similarly, it stimulated angiogenesis by promoting endothelial cell migration up to approximately 4 fold and interestingly tube formation up to 8.5 fold (p < 0.01). Furthermore, vitamin A treatment was shown to decrease the level of nitric oxide production in a dose-dependent effect (p < 0.05), exhibiting the anti-inflammatory property of vitamin A in accelerating wound healing. These results may reveal the therapeutic potential of vitamin A in diabetic wound healing by stimulating regeneration, angiogenesis, and anti-inflammation responses.

In vitro and in vivo evaluation of the anti-inflammatory effects of Arzanol from Helichrysum italicum

Planta Medica ◽  
2010 ◽  
Vol 76 (12) ◽  
Author(s):  
J Bauer ◽  
F Dehm ◽  
A Koeberle ◽  
F Pollastro ◽  
G Appendino ◽  
...  
Keyword(s):  
In Vivo Evaluation ◽  
Anti Inflammatory

In vitro anti-inflammatory and wound healing activities of Citrus auraptene

Planta Medica ◽  
2012 ◽  
Vol 78 (11) ◽  
Author(s):  
F Epifano ◽  
S Genovese ◽  
L Zhao ◽  
V Dang La ◽  
D Grenier
Keyword(s):  
Wound Healing ◽  
Anti Inflammatory

Evaluation of in vitro anti-inflammatory effects of the remaining water subextract of Cistus laurifolius leaves

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
İ Atay ◽  
AZ İlter ◽  
Y Bağatur ◽  
D Telci ◽  
H Kırmızıbekmez ◽  
...  
Keyword(s):  
Anti Inflammatory

Haemanthus coccineus extract shows profound anti-inflammatory actions in vitro and in vivo due to its main alkaloid narciclasine

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
S Fuchs ◽  
LT Hsieh ◽  
W Saarberg ◽  
CAJ Erdelmeier ◽  
TA Wichelhaus ◽  
...  
Keyword(s):  
Anti Inflammatory

Cannabis tinctures and extracts – in vitro profiling for cytotoxic and anti-inflammatory effects

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
W Peschel ◽  
M Politi ◽  
N Wilson ◽  
A Constanti ◽  
JM Prieto Garcia ◽  
...  
Keyword(s):  
Anti Inflammatory

In vitro anti-inflammatory activity of extracts from seeds of some Nigella species

Planta Medica ◽  
2007 ◽  
Vol 73 (09) ◽  
Author(s):  
P Landa ◽  
P Marsik ◽  
T Vanek ◽  
L Kokoska
Keyword(s):  
Inflammatory Activity ◽  
Anti Inflammatory
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