SCREENING FITOQUÍMICO, ANÁLISE CITOTÓXICA E ANTIMICROBIANA DO EXTRATO DAS FOLHAS DE ANNONA MURICATA L. (1753) (ANNONACEAE)

2021 ◽  
pp. 208-219
Author(s):  
Heloíza Rabêlo Cunha ◽  
Patrick de Castro Cantuária ◽  
Elizabeth Viana Moraes da Costa ◽  
Ana Luzia Ferreira Farias ◽  
José Policarpo Miranda Júnior ◽  
...  
Keyword(s):  
Annona Muricata

PRODUCCIÓN DE GUANÁBANA (Annona muricata L.) EN ALTA DENSIDAD DE PLANTACIÓN, COMO ALTERNATIVA PARA PRODUCTORES CON SUPERFICIES REDUCIDAS

2018 ◽  
Vol 11 (9) ◽  
Author(s):  
E. Aceves-Navarro
Keyword(s):  
Annona Muricata ◽  
El Sistema

En México el 63% de los productores cultivan menos de cinco hectáreas agrícolas, por lo que es importante diseñar y desarrollar estrategias para aumentar la productividad en superficies pequeñas. En este trabajo se presentan los resultados de investigación obtenidos durante 2015 a 2017, en una huerta de guanábana (Annona muricata L.) establecida en alta densidad de plantación con 2,222 plantas ha-1 (3X1.5 m). El estudio se inició cuando las plantas tenían ocho años de edad y concluyó a la edad de 10. Con la densidad evaluada se obtuvo, en los tres años de estudio, una producción promediode fruto de 28 t ha-1. Un aspecto sobresaliente de la tecnología validada, es el sistema de podas, que permitió mantener arboles de talla baja y cosechar la fruta manualmente, sin usar implementos como escaleras o bajadores, evitando daños mecánicos; así mismo, esta tecnología permitió tener un control más eficiente de organismos plaga, facilitar el manejo de los programas de riego y fertilización. Cuando se aplica esta tecnología, después del octavo año de producción, el productor tiene ingresos anuales promedio de hasta $663,873.49 pesos (USD$33200.00) de utilidad por hectárea.

Viabilidade Celular de Cultura de Linfócitos Tratados com Annona muricata L.

2010 ◽  
Vol 12 (24) ◽  
pp. 95-101 ◽  
Author(s):  
C. Dani ◽  
J.C. Aginoni ◽  
C. Calloni ◽  
M. Salvador ◽  
P.D.S. Spada
Keyword(s):  
Annona Muricata

Diabetogenic Potential of Dexamethasone and Effect of Annona Muricata Methanolic Bark Extract as Post-exposure Therapy in Albino Rats

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 131-LB
Author(s):  
TUNBOSUN A. OLADIPO ◽  
YEMISI D. ADEOYE ◽  
OLUWAMAYOWA O. OLADIPO ◽  
JOHNNY O. OLUKUNLE
Keyword(s):  
Exposure Therapy ◽  
Bark Extract ◽  
Albino Rats ◽  
Annona Muricata ◽  
Post Exposure

scholarly journals Kinetic Model of Moisture Diffusivity in Soursop Leaves (Annona muricata L.) by Convection Drying

2020 ◽  
Vol 991 ◽  
pp. 012107
Author(s):  
T T Y Nhi ◽  
P V Thinh ◽  
N D Vu ◽  
N T Bay ◽  
N T M Tho ◽  
...  
Keyword(s):  
Kinetic Model ◽  
Moisture Diffusivity ◽  
Annona Muricata

Annona muricata silver nanoparticles exhibit strong anticancer activities against cervical and prostate adenocarcinomas through regulation of CASP9 and the CXCL1/CXCR2 genes axis

Tumor Biology ◽  
2021 ◽  
Vol 43 (1) ◽  
pp. 37-55
Author(s):  
Yahaya Gavamukulya ◽  
Esther N. Maina ◽  
Hany A. El-Shemy ◽  
Amos M. Meroka ◽  
Geoffrey K. Kangogo ◽  
...  
Keyword(s):  
Silver Nanoparticles ◽  
Anticancer Drugs ◽  
Hela Cells ◽  
Selectivity Index ◽  
Annona Muricata ◽  
Anticancer Activities ◽  
Apoptosis Pathway ◽  
Migration Assay ◽  
Intrinsic Apoptosis Pathway ◽  
In Cells

BACKGROUND: Green synthesized nanoparticles have been earmarked for use in nanomedicine including for the development of better anticancer drugs. OBJECTIVE: The aim of this study was to undertake biochemical evaluation of anticancer activities of green synthesized silver nanoparticles (AgNPs) from ethanolic extracts of fruits (AgNPs-F) and leaves (AgNPs-L) of Annona muricata. METHODS: Previously synthesized silver nanoparticles were used for the study. The effects of the AgNPs and 5-Fluorouracil were studied on PC3, HeLa and PNT1A cells. The resazurin, migration and colonogenic assays as well as qRT-PCR were employed. RESULTS: The AgNPs-F displayed significant antiproliferative effects against HeLa cells with an IC50 of 38.58μg/ml and PC3 cells with an IC50 of 48.17μg/ml but selectively spared normal PNT1A cells (selectivity index of 7.8), in comparison with first line drug 5FU and AgNPs-L whose selectivity index were 3.56 and 2.26 respectively. The migration assay revealed potential inhibition of the metastatic activity of the cells by the AgNPs-F while the colonogenic assay indicated the permanent effect of the AgNPs-F on the cancer cells yet being reversible on the normal cells in contrast with 5FU and AgNPs-L. CASP9 was significantly over expressed in all HeLa cells treated with the AgNPs-F (1.53-fold), AgNPs-L (1.52-fold) and 5FU (4.30-fold). CXCL1 was under expressed in HeLa cells treated with AgNPs-F (0.69-fold) and AgNPs-L (0.58-fold) and over expressed in cells treated with 5FU (4.95-fold), but the difference was not statistically significant. CXCR2 was significantly over expressed in HeLa cells treated with 5FU (8.66-fold) and AgNPs-F (1.12-fold) but under expressed in cells treated with AgNPs-L (0.76-fold). CONCLUSIONS: Here we show that biosynthesized AgNPs especially AgNPs-F can be used in the development of novel and better anticancer drugs. The mechanism of action of the AgNPs involves activation of the intrinsic apoptosis pathway through upregulation of CASP9 and concerted down regulation of the CXCL1/ CXCR2 gene axis.

scholarly journals Postharvest disease management of Alternaria spots on tomato fruit by Annona muricata fruit extracts

2021 ◽  
Author(s):  
Humaira Rizwana ◽  
Najat A. Bokahri ◽  
Sarah A. Alsahli ◽  
Amal S. Al Showiman ◽  
Rawan M. Alzahrani ◽  
...  
Keyword(s):  
Disease Management ◽  
Tomato Fruit ◽  
Postharvest Disease ◽  
Annona Muricata ◽  
Fruit Extracts

scholarly journals Phytochemical and Antioxidant Dynamics of the Soursop Fruit (Annona muricata L.) in response to Colletotrichum spp.

2020 ◽  
Vol 2020 ◽  
pp. 1-12
Author(s):  
Alejandro Rubio-Melgarejo ◽  
Rosendo Balois-Morales ◽  
Yolotzin Apatzingan Palomino-Hermosillo ◽  
Graciela Guadalupe López-Guzmán ◽  
José Carmen Ramírez-Ramírez ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Antiradical Activity ◽  
Late Response ◽  
Total Phenols ◽  
Annona Muricata ◽  
Coumaric Acid ◽  
Colletotrichum Siamense ◽  
Soluble Phenols ◽  
Colletotrichum Spp ◽  
Higher Sensitivity

This work evaluates the effect of the pathogens Colletotrichum siamense and C. gloeosporioides on the response of soursop fruits. The bioactive compounds (total phenols, flavonoids, anthraquinones, coumarins, steroids, terpenoids, alkaloids, and saponins) were evaluated qualitatively in soursop pulp. Positive phytochemicals and antioxidant activity (DPPH•, ABTS•+, and FRAP) were quantified at day zero, one, three, and five. Fruits treated with C. gloeosporioides showed higher disease severity (P<0.05). Early fruit response (day one) was observed with both pathogens, increased the concentration of saponins and repressed the production of quercetin 3-O-glucoside (P<0.05). Likewise, C. siamense decreased total soluble phenols and flavonoids and increased antiradical activity DPPH•. Besides, C. gloeosporioides decreased the levels of kaempferol 3-O-rutinoside and ferulic acid (P<0.05). Regarding the late response (day three), both pathogens decreased the concentration of saponins and increased flavonoids and phytosterols (P<0.05). Nevertheless, C. siamense increased the levels of total soluble phenols, p-coumaric acid, kaempferol, and antiradical activity FRAP (P<0.05). Also, C. gloeosporioides repressed the production of quercetin 3-O-glucoside at day five (P<0.05). Soursop fruits had a response to the attack of Colletotrichum during ripening at physicochemical and oxidative levels, which is associated with the production of compounds related to the development inhibition of pathogens. Even so, soursop fruits showed higher susceptibility to C. gloeosporioides and higher sensitivity to the attack of C. siamense.

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