scholarly journals Frequency Analysis Results Distribution of C589t Rs2243250 Polymorphism in Il4 Gene Among Patients with Chronic Rhinosinusitis

2021 ◽  
pp. 486-492
Author(s):  
Djuraev JA ◽  
Khasanov US ◽  
Vokhidov UN ◽  
Botirov AJ
Keyword(s):  
De Novo ◽  
Individual Characteristics ◽  
The Body ◽  
De Novo Synthesis ◽  
Effector Cells ◽  
Gm Csf ◽  
Regulatory Systems ◽  
Biological Medicine ◽  
The Individual ◽  
High Technologies

The fairly widespread prevalence of CRSwNP along with the lack of remedies for curing the disease, a variety of hypotheses of etiology dictate the need for further study of all links in the pathogenesis and clinical features of the course of the disease. In the coming century of “biological medicine”, the availability of high technologies of medical genetics makes it possible to reveal the individual characteristics of the most important regulatory systems of the body, which opens up new prospects for studying the etiology and pathogenesis of CRSwNP. In the tissues of polyps and intranasal secretions, an increase in the concentration of various inflammatory mediators, in particular interleukins, is observed due to an increase in their de novo synthesis by effector cells. Particular importance is attached to an increase in the concentration of cytokines involved in the development, recruitment and activation of eosinophils (IL-4, IL-12, IL-13, GM-CSF), the main pro-inflammatory (IL-1, IL-2, TNF-a, IL- 10), regulatory cytokines (IL-10, TLR2B), contributing to the chronicity of the inflammatory process in the nasal cavity.

scholarly journals Relationship between Symptoms in Women with Endometriosis and Lifestyles: a Qualitative Interview Study

2020 ◽  
Vol 4 (4) ◽  
pp. 178-183
Author(s):  
M. Scavone ◽  
C. Gizzi ◽  
E. Albi
Keyword(s):  
Physical Activity ◽  
Uterine Cavity ◽  
Individual Characteristics ◽  
The Body ◽  
Quality Of Sleep ◽  
Qualitative Interview Study ◽  
Italian Women ◽  
The Individual ◽  
Reproductive Aged Women

AbstractEndometriosis is a common condition that affects reproductive-aged women and is characterized by the presence of endo-metrial tissue outside the uterine cavity with nodules and lesions. The study aimed to analyze lifestyles of women affected by endometriosis in relation with their symptoms. In this observational study, 735 Italian women have been interviewed online through a questionnaire structured in two parts. The first part was mainly anamnestic, focused on gathering information about the age, the stage of disease, comorbidities, involved organs, symptomatology, chirurgical treatment, induced menopause. The second part focused on the individual characteristics and lifestyle of the patients such as the body mass index, physical activity, quality of sleep, and the diet. The results showed how a healthy diet and a regular physical activity reduce drastically the symptoms of the patients.

scholarly journals A comparative analysis of the relationship between stature and ultrasound dimensions of internal organs in adolescents

2021 ◽  
Vol 12 (2) ◽  
pp. 19-27
Author(s):  
Valerii O. Yerkudov ◽  
Andrey P. Pugovkin ◽  
Aleksej J. Volkov ◽  
Oksana I. Musaeva ◽  
Dmitriy J. Volkov ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Body Length ◽  
Individual Characteristics ◽  
The Body ◽  
Comparative Characteristic ◽  
Z Score ◽  
Internal Organs ◽  
Average Group ◽  
The Individual ◽  
The Relationship

The aim of the study was a comparative characteristic of the size of internal organs according to ultrasonography data in subjects with various deviations in stature, determined using international standardized norms. Materials and methods. The stature was measured in 93 adolescents, aged 13 to 17 years. Based on the measurements, the Z-score of body length was calculated according to the WHO Growth Reference, 2007 and three groups were formed for comparing the sizes of internal organs: average, above average, below average. Ultrasonography data of the internal organs dimensions and thyroid gland was performed using a Toshiba Aplio 500 ultrasound scanner. Results. There were statistically significantly lower values of the liver span and the longitudinal size of the gallbladder in the examined subjects from the below average group compared to the rest of the subjects. The length of the spleen and the total volume of the thyroid gland were statistically significantly different in subjects from all three groups, with the highest values in volunteers from the above average group. A weak direct correlation was shown between the Z-score of body length and liver span, the length of the cauda of the pancreas, and the width of the spleen. An average direct statistical relationship was found between the Z-score of stature and the length of the spleen, as well as the total volume of the thyroid gland. Conclusion. To a greater extent, body length is associated with the size of the parenchymal organs with a pronounced connective tissue frame - the liver and spleen, as well as the thyroid gland due to the relationship of its volume with hormones that regulate growth and development. Clinical substantiation of the relationship between the structure of the body and internal organs opens up the possibility of creating anatomical standards that allow ultrasound morphometric assessment of internal organs, taking into account the individual characteristics of the patients body size.

scholarly journals Hypoergy and its significance in the course of infections

2021 ◽  
Vol 30 (9) ◽  
pp. 895-903
Author(s):  
N. N. Sirotinin
Keyword(s):  
Biological Properties ◽  
Individual Characteristics ◽  
The Body ◽  
Ancient Medicine ◽  
Sextus Empiricus ◽  
The Individual

Ancient medicine, characterized by great observation, attached great importance to the reactivity of the body in the occurrence of various diseases. Already then, Ptolemy Dioscorides and Sextus Empiricus spoke of idiosyncrasies, and Galen introduced the doctrine of idiopathies. In subsequent periods, this question has always received attention and has never been so ignored as at the end of the last century, when in connection with the blossoming of microbiology they looked for the cause of the different course of diseases in the character of the biological properties of the microorganism, while forgetting the individual characteristics of the organism itself.

Biobehavioral Factors in Chemotherapy-Induced Nausea and Vomiting

2004 ◽  
Vol 2 (5) ◽  
pp. 501-508 ◽  
Author(s):  
Joseph A. Roscoe ◽  
Gary R. Morrow ◽  
Jane T. Hickok ◽  
Karen M. Mustian ◽  
Abhay R. Shelke
Keyword(s):  
Warning Signal ◽  
Brain Structures ◽  
Individual Characteristics ◽  
The Body ◽  
Nausea And Vomiting ◽  
Chemotherapy Treatment ◽  
The Individual

Although emesis can be considered a reflex to clear toxins from the body and involves mostly lower brain structures, nausea's purpose appears to be a warning signal to the individual to not engage in behaviors that he or she was doing at the time. As such, it involves the functioning of cognition and memory from higher developed neural structures. Given this, it should not be surprising that biobehavioral factors are important in predicting and controlling nausea. This article reviews the individual characteristics that are clinically useful in predicting which patients will have an increased probability of experiencing nausea or emesis during chemotherapy treatment, and also briefly review psychologic and biobehavioral treatments that can be useful in managing chemotherapy-related nausea.

scholarly journals Dynamic prediction based on variability of a longitudinal biomarker

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Kristen R. Campbell ◽  
Rui Martins ◽  
Scott Davis ◽  
Elizabeth Juarez-Colunga
Keyword(s):  
Adverse Events ◽  
De Novo ◽  
Predictive Ability ◽  
Predictive Performance ◽  
The Body ◽  
Warning Sign ◽  
Dynamic Prediction ◽  
Post Transplant ◽  
The Individual ◽  
Over Time

Abstract Background Tacrolimus is given post-kidney transplant to suppress the immune system, and the amount of drug in the body is measured frequently. Higher variability over time may be indicative of poor drug adherence, leading to more adverse events. It is important to account for the variation in Tacrolimus, not just the average change over time. Methods Using data from the University of Colorado, we compare methods of assessing how the variability in Tacrolimus influences the hazard of de novo Donor Specific Antibodies (dnDSA), an early warning sign of graft failure. We compare multiple joint models in terms of fit and predictive ability. We explain that the models that account for the individual-specific variability over time have the best predictive performance. These models allowed each patient to have an individual-specific random error term in the longitudinal Tacrolimus model, and linked this to the hazard of dnDSA model. Results The hazard for the variance and coefficient of variation (CV) loading parameter were greater than 1, indicating that higher variability of Tacrolimus had a higher hazard of dnDSA. Introducing the individual-specific variability improved the fit, leading to more accurate predictions about the individual-specific time-to-dnDSA. Conclusions We showed that the individual’s variability in Tacrolimus is an important metric in predicting long-term adverse events in kidney transplantation. This is an important step in personalizing the dosage of TAC post-transplant to improve outcomes post-transplant.

scholarly journals THE INFLUENCE OF SPORTS ACTIVITY ON THE IMPORTANCE OF THE SEXUAL SOMATOTYPE OF ATHLETES IN PAIRED WOMEN’S ACROBATICS AND GYMNASTICS

2021 ◽  
pp. 66-73
Author(s):  
Кonstantin Bugaevsky ◽  
Lina Rybalko ◽  
Tetiana Synytsya ◽  
Marek Napierała ◽  
Olga Smoleńska ◽  
...  
Keyword(s):  
Female Athletes ◽  
Individual Characteristics ◽  
The Body ◽  
Literary Analysis ◽  
Ratio Method ◽  
Sources Of Information ◽  
Sports Activity ◽  
Female Partners ◽  
Paired Female ◽  
The Individual

The article presents research materials relating to the study of the individual characteristics of the 2D:4D finger index in young athletes in pair female acrobatics and gymnastics. The aim of the study is to study and comparatively analyze the features of the 2D: 4D finger proportions in the "upper" and "lower" female partners in paired female acrobatics and among the female athletes involved in artistic gymnastics, referred to adolescence; confirmation of the influence of the 2D:4D finger ratio on the athletic capabilities of athletes and the formation of their sexual somatotype. It has been proved that the presence in these groups of female athletes with certain values of the inverse, andromorphic sexual somatotype indicates an increased level of testosterone in the body of these athletes and inverse adaptive changes with the formation of masculinization phenomena in them. Research methods and organization. To conduct research on the features of the 2D:4D finger proportions in the "upper" and "lower" female partner athletes in paired female acrobatics and in athletes engaged in artistic gymnastics, the following methods were used: anthropometric method to determine: IPD) and somatotyping according to the classification of J. Tanner and W. Marshall; 2) measurement and comparison of II and IV fingers of the hands of athletes using the finger ratio method according to J.T. Menning – 2D:4D Digit Ratio; 3) as well as the method of literary analysis, using available sources of information; 4) method of mathematical statistics. Organization of the study. This study was conducted in 2019-2020 with the involvement of 31 pairs of acrobats and 59 athletes involved in artistic gymnastics in Ukraine (Nikolaev and Poltava). "Lower" acrobats and gymnasts (n=90) - adolescent – 19.35±1.07 years; "Upper" acrobats (n=31) – pubertal age – 14.68±1.14 years (p≤0,01). Their experience in these sports ranged from 2.5 to 10 years. The level of sportsmanship – from I-III sports category to a candidate for master of sports, master of sports. Research results. After carrying out the study of the necessary anthropometric measurements for each participant (indicators of the width of the shoulders and pelvis, the length of the II and IV fingers of both hands) and processing the obtained anthropometric values, the values of the sexual dimorphism index (SDI) in each study group were determined by mathematical recalculation.

scholarly journals Opportunities for evaluation of students learning achievements in the process of basketball taking into account the individual features of the development of the organism

2021 ◽  
pp. 140-142
Author(s):  
Pen Chen
Keyword(s):  
Student Achievement ◽  
Physical Education ◽  
Individual Characteristics ◽  
The Body ◽  
Physical Culture ◽  
Regression Equations ◽  
Academic Achievements ◽  
Culture And Health ◽  
The Individual ◽  
Technical Readiness

The article substantiates the need to define clear and universal criteria for assessing the academic achievements of students in physical education in the conditions of sectional classes on the selected type of physical culture and health activities. Possibilities of increasing t he objectivity of assessing the success of basketball classes based on taking into account the individual characteristics of the development of the student's body are revealed. An attempt is made to determine the informative indicators of the development of the body of students that affect the game efficiency in basketball. The results of research of interrelation of motor and anthropometric indicators with results of performance of technical receptions in basketball are presented. Possibilities for development of mathematical models of proper norms of technical readiness of students in the process of teaching basketball in the form of regression equations that can be used as criteria for assessing student achievement in sectional classes are identified.

scholarly journals ОСОБЛИВОСТІ ФОРМОУТВОРЕННЯ ГЛАМУРНОГО КОСТЮМА 1930–1950-х РОКІВ

2018 ◽  
pp. 65-74
Author(s):  
В. В. Будяк
Keyword(s):  
Professional Training ◽  
Individual Characteristics ◽  
The Body ◽  
Practical Significance ◽  
Design Practice ◽  
Historical Method ◽  
Film Studios ◽  
The Aesthetic ◽  
The Individual

To analyze the costumes of Hollywood actresses in the period 1930 – 1950's, which became the basis for the formation of typical structures of a glamor costume in the XX century; to establish the peculiarities of their formation and to determine their place in the structure of a fashionable costume of the beginning of the XXI century.  The stylistic and associative methods of studying the artistic compositional features of the glamorous outfit of actresses as a creative source in contemporary design practice have been used, the comparative-historical method and the method of system-comparative analysis have been applied, which allowed to carry out the general typology of structures of a glamor suit of a certain period and to establish the peculiarities of its formation.  The research shows how in 1930 – 1950's designers of American film studios developed stylistics of a glamorous suit, focusing on the individual characteristics of the body of the structure and appearance of the actresses, their role in the film industry. The results obtained concerning the structures of costumes of actresses and the peculiarities of their formation make it possible to characterize the artistic and compositional features of a glamorous costume and to show that they became the basis for the formation of typical images, and eventually – the typological structures of a glamor style suit, which before that time remain relevant and practically unchanged in the design of promising forms of clothing in stylistics of glamor. The peculiarities of the formation of a glamor suit in a certain period are established; outlined the formative searches of the designers of the cinema industry in the development of stylistics of glamor, which was reflected, first of all, in the formation of typical costume structures, its silhouette forms, constructive-compositional solution, the application of materials and their decorating; the basic means of embodiment of typical figurative-stylistic and formal-compositional signs of style of glamor in modern design practice are established. The practical significance of the work lies in the fact that the main results of the study may be useful for the development and production of clothing collections in the style of glamor; Provide capacious information on figurative-stylistic and formally-constructive characteristics of the typical glamor style of costume structures, silhouette forms and methods of shaping in general. The results can be used in the professional training of designers in order to improve the quality of design and art solutions in the development of collections of fashionable clothing that meet the aesthetic demands of contemporaries.

scholarly journals Brainwaves feature classification by applying K-Means clustering using single-sensor EEG

2016 ◽  
Vol 2 (3) ◽  
pp. 167 ◽  
Author(s):  
Ahmad Azhari ◽  
Leonel Hernandez
Keyword(s):  
Brain Activity ◽  
Cognitive Activity ◽  
Individual Characteristics ◽  
The Body ◽  
Biometric Technology ◽  
Left Brain ◽  
Single Sensor ◽  
Math Activity ◽  
The Individual ◽  
The Right

The use of brainwave signal is a step in the introduction of the individual identity using biometric technology based on characteristics of the body. Brainwave signal has unique characteristics and different on each individual because the brainwave cannot be read or copied by people so it is not possible to have a similarity of one person with another person. To be able to process the identification of individual characteristics, which obtained from the signal brainwave, required a pattern of brain activity that is prominent and constant. Cognitive activity testing using a single-sensor EEG (Electroencephalogram) divided into two categories, called the activity of cognitive involving the ability of the right brain (creativity, imagination, holistic thinking, intuition, arts, rhythms, nonverbal, feelings, visualization, tune of songs, daydreaming) and the left brain (logic, analysis, sequences, linear, mathematics, language, facts, think in words, word of songs, computation) give a different cluster based on two times the test on mathematical activities (no cluster slices of experiment 1 and experiment 2). The result showed that cognitive activity based on math activity can provide a signal characteristic that can be used as the basis for a brain-computer interface applications development by utilizing EEG single-sensor.

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