scholarly journals Oral Health-Related Quality of Life in Patients with Dystrophic Epidermolysis Bullosa

2018 ◽  
Vol 2 (2) ◽  
pp. 43-59 ◽  
Author(s):  
Giulio Fortuna ◽  
Massimo Aria ◽  
Sarah Whitmire ◽  
Rodrigo Cepeda-Valdes ◽  
Sandra Cecilia Garcia-Garcia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Epidermolysis Bullosa ◽  
Health Related Quality ◽  
Dystrophic Epidermolysis Bullosa ◽  
Sf 36 ◽  
General Quality ◽  
Related Quality ◽  
Health Related

Background: Dystrophic epidermolysis bullosa (DEB) is a devastating mucocutaneous inherited disorder that can have a remarkable impact on the oral cavity. Objective: To understand the relationships between oral health-related quality of life and general quality of life in DEB patients versus a control group. Methods: Twenty-eight DEB patients and 26 healthy individuals completed the following battery of scales: Oral Health Impact Profile (OHIP-49), RAND Short Form-36 (SF-36), Hamilton Rating Scale for anxiety (HAM-A) and depression (HAM-D). Results: All 7 dimensions in OHIP-49 demonstrated significant difference in functional limitations (Median:13.0; IQR:10.3-20.0 vs Median:7.0; IQR:2.0-9.0; p<0.001) and physical disability (Median:11.5; IQR:4.0-15.0 vs Median:0.0; IQR:0.0-2.3; p<0.001) in DEB patients vs controls, respectively. In SF-36, physical functioning and general health were highly significant (p<0.001), whereas limitation due to physical health (p=0.043) and pain (p=0.010) were moderately significant. A positive correlation was found between oral health-related quality of life and anxiety (p=0.005 and p=0.03 in DEB patients and controls, respectively) and depression (p=0.045 and p=0.001 in DEB patients and controls, respectively). In DEB patients, no correlation was found between general quality of life and anxiety/depression, oral health-related quality of life and oral-pharyngeal severity score, number of oral-pharyngeal sites involved and general quality of life, as well as oral health-related quality of life between patients with dominant and recessive DEB forms (p>0.05). Conclusions: The oral health-related quality of life is highly impaired in patients with DEB. General quality of life was affected only for some dimensions and was not correlated with oral health-related quality of life.

Oral Health-related Quality of Life in Patients with Dystrophic Epidermolysis Bullosa

2016 ◽  
Author(s):  
Giulio Fortuna ◽  
Massimo Aria ◽  
Sarah Whitmire ◽  
Rodrigo Cepeda-Valdes ◽  
Sandra Cecilia Garcia-Garcia ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Epidermolysis Bullosa ◽  
Health Related Quality ◽  
Dystrophic Epidermolysis Bullosa ◽  
Related Quality ◽  
Health Related

scholarly journals Oral health-related quality of life in patients with heart failure and left ventricular assist devices—results of a cross-sectional study

2021 ◽  
Author(s):  
Gerhard Schmalz ◽  
Christian Binner ◽  
Mirjam Eisner ◽  
Justus Wagner ◽  
Josephine Rast ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
Short Form ◽  
Left Ventricular ◽  
Health Related Quality ◽  
Cross Sectional ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related

Abstract Objectives The aim of this cross-sectional study was to compare oral health-related quality of life (OHRQoL) of patients with left ventricular assist device (LVAD) and heart failure (HF). Material and methods Seventy-four patients with LVAD were recruited from University Department for Cardiac Surgery, Leipzig Heart Center, Germany. A group of 72 patients with HF was composed by matching (age, gender, smoking). The German short form of oral health impact profile (OHIP G14) was applied. Health-related quality of life (HRQoL) was measured by short form 36 survey (SF-36). Dental conditions (decayed-, missing- and filled-teeth [DMF-T]), remaining teeth and periodontal findings were assessed. Statistics: t-test, Mann-Whitney U test, Kruskal-Wallis test, chi-square or Fisher test, linear regression. Results Age, gender, smoking, underlying disease, co-morbidities and oral findings were comparable between groups (p > 0.05). OHIP G14 sum score was 3.53 ± 6.82 (LVAD) and 2.92 ± 5.35 (HF; p = 0.70), respectively. The scales SF-36 physical functioning (p = 0.05) and SF-36 social functioning (p < 0.01) were worse in LVAD. In the LVAD group, the DMF-T and remaining teeth negatively correlated with OHIP G14 sum score (p < 0.01). In HF patients, positive correlations were found between OHIP G14 and D-T (p < 0.01) and remaining teeth (p = 0.04). Moreover, DMF-T (p = 0.03) and remaining molars/premolars (p = 0.02) were negatively correlated with SF-36 scales in HF. Conclusions Oral health and OHRQoL was comparable between LVAD and HF; thereby, OHRQoL reflected the clinical oral status. Clinical relevance Dental care, with beginning in early stage of HF, should be fostered to preserve teeth and support quality of life before and after LVAD implantation.

scholarly journals Relation Between Clinical Oral Health Status, Oral Health Related Quality of Life, Denture Material Type and Self-perceived General Health, in a General Population

2019 ◽  
Vol 70 (9) ◽  
pp. 3315-3324
Author(s):  
Alexandru Gratian Grecu ◽  
Andra Elena Aungurencei ◽  
Dan Lucian Dumitrascu
Keyword(s):  
Quality Of Life ◽  
Oral Health ◽  
General Health ◽  
Oral Health Status ◽  
Health Related Quality ◽  
Sf 36 ◽  
Related Quality ◽  
Health Related ◽  
The Mean

The purpose of the current study was to assess the oral health related quality of life (OHRQoL), general health related quality of life (HRQoL), clinical oral and denture status, as well as their interrelation, within a hospitalized general population. The Romanian versions of the Oral Health Impact Profile-49 (OHIP-49Ro), SF-36 questionnaires, together with an additional set of oral health assessment questions, were administered under the interview format to 170 patients, hospitalized in the Second Medical Clinic of Internal Medicine, Cluj-Napoca, Romania. The patients also underwent clinical examination, based on which the DMFT was calculated. Denture status, was as well, registered, together with the denture material. Each patient provided informed consent, prior to any examination. Questionnaire scores were calculated and used for the univariate descriptive statistics, reflecting oral health, OHRQoL and HRQoL sample tendencies. Successively, multiple regression analysis was applied, with the purpose of investigating the relationship between: the clinical oral health status, OHRQoL and HRQoL. In the first model, OHRQoL, while in the second model the dependent variable was represented by the HRQoL, each having a set of established predictors. Additionally, for denture wearing patients, OHRQoL variations in respect to the denture material were assessed, using one-way ANOVA. The mean OHIP-49Ro overall score was 31.90. The mean SF-36 subscales score was 60.66. The mean DMFT score was 18.47. For both regression analyses, all the regression models were significant. For the first model, the predictors accounted for 48.5% of variance in OHRQoL. For the second model, the highest percent of variance, explained by the predictors, was registered for the Mental Health subscale (22.8%). DMFT, as a clinical measure, was a statistically significant predictor rather for the perception in general health. However, OHRQoL was a good predictor for HRQoL, as an integrated part of it. Moreover, the one-way ANOVA indicated statistically significant differences in OHRQoL perception, in respect to the denture material F(2, 82) = 3.253, p = 0.044. The current study indicated complex relations between the patients� clinical status, the OHRQoL and HRQoL. The clinical determinants presented direct impact on both OHRQoL and HRQoL. More balanced HRQoL scores suggested that patients focused more on the perception of general health outcomes.

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