Epidemiology, Prevalence And Incidence in Pachychoroid Disease Spectrum

2020 ◽  
pp. 57-91
Keyword(s):  
Risk Factors ◽  
Central Serous Chorioretinopathy ◽  
Polypoidal Choroidal Vasculopathy ◽  
Disease Spectrum ◽  
Focal Choroidal Excavation ◽  
Pachychoroid Neovasculopathy ◽  
Novel Concept ◽  
Pathogenic Process ◽  
Choroidal Vasculopathy ◽  
Pachychoroid Pigment Epitheliopathy

Pachychoroid is a relatively novel concept describing a phenotype characterized by increased choroidal thickening, pathologically dilated veins in the Haller’s layer (pachy-veins), thinning in Sattler’s and choriocapillaris layers. The spectrum comprises the following disease groups: Pachychoroid Pigment Epitheliopathy, Central Serous Chorioretinopathy, Pachychoroid Neovasculopathy, Polypoidal Choroidal Vasculopathy, Focal choroidal excavation, Peripapillary pachychoroid syndrome. These conditions all exhibit the characteristic choroidal alterations and are believed to represent different manifestations of a common pathogenic process. The aim of this review is to exhibit the epidemiology, risk factors, incidence and prevalence of the pachychoroid diseases respectively.

Overview and Classification of Pachycoroid Spectrum Diseases

2020 ◽  
pp. 67-74
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Focal Choroidal Excavation ◽  
Current Review ◽  
Pachychoroid Neovasculopathy ◽  
Characteristic Features ◽  
Choroidal Vasculopathy ◽  
Pachychoroid Pigment Epitheliopathy

Pachychoroid spectrum has been defined recently and the diseases of this spectrum share some common choroidal features. The aim of the current review is to provide an overview of characteristic features and classification of pachychoroid spectrum including uncomplicated pachychoroid, pachychoroid pigment epitheliopathy, central serous chorioretinopathy, pachychoroid neovasculopathy, polipoidal choroidal vasculopathy, peripapillary pachychoroid syndrome, and focal choroidal excavation.

scholarly journals The implications of subretinal fluid in pachychoroid neovasculopathy

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Geun Woo Lee ◽  
Hyeon Cheol Roh ◽  
Se Woong Kang ◽  
A. Young Kim ◽  
Hoon Noh ◽  
...  
Keyword(s):  
Central Serous Chorioretinopathy ◽  
Polypoidal Choroidal Vasculopathy ◽  
Multimodal Imaging ◽  
Optical Coherence Tomography Angiography ◽  
Subretinal Fluid ◽  
Longitudinal Changes ◽  
History Of ◽  
Pachychoroid Neovasculopathy ◽  
Choroidal Vasculopathy ◽  
Epidemiological Parameters

AbstractThis study aimed to identify the clinical characteristics and longitudinal changes in exudative pachychoroid neovasculopathy (PNV) and non-exudative PNV. This retrospective cohort study involved 81 eyes of PNV diagnosed by multimodal imaging including optical coherence tomography angiography. At baseline, they were divided into exudative PNV group and non-exudative PNV group depending on the presence of subretinal fluid. The clinical features of both groups and the longitudinal changes were investigated and compared. There were 55 eyes with non-exudative PNV and 26 eyes with exudative PNV. Individuals with non-exudative PNV were older, more frequently asymptomatic and had a higher prevalence of polypoidal choroidal vasculopathy in the opposite eye (all P’s < 0.05). Whereas individuals with exudative PNV showed thicker choroid and more frequent history of central serous chorioretinopathy (all P’s < 0.001). During about 12 months of longitudinal observation, the transformation into polypoidal choroidal vasculopathy was noted in 4 eyes of non-exudative PNV group, whereas in none of the exudative PNV group. Exudative PNV and non-exudative PNV seem to be separate entities with different epidemiological parameters. Non-exudative PNV, which is frequently found without symptoms at an older age, is suspected to be the significant precursor lesion of polypoidal choroidal vasculopathy. In contrast, exudative PNV may share the same pathophysiology as central serous chorioretinopathy.

Genetics, Risk Factors and Pathogenesis in the Spectrum of Pachychoroid Diseases

2020 ◽  
pp. 62-66
Keyword(s):  
Risk Factors ◽  
Pigment Epithelium ◽  
Retinal Pigment ◽  
Focal Choroidal Excavation ◽  
Pachychoroid Neovasculopathy ◽  
Choroidal Vessels ◽  
Angiographic Findings ◽  
Choroidal Vascular Hyperpermeability ◽  
Choroidal Hyperpermeability ◽  
Pachychoroid Pigment Epitheliopathy

The spectrum of pachychoroid disease was first described by Warrow et al. in 2013. The characteristics of pachyoroid phenotype are dilatation of the vessels in the Haller layer (pachyvessels), thinning of the layers of Sattler, and choriocapillaris. Dilated choroidal vessels, choroidal hyperpermeability, diffuse or focal choroidal thickness and associated with progressive retinal pigment epithelium (RPE) dysfunction are thought to be in the pathogenesis. Angiographic findings such as choroidal vascular hyperpermeability, especially in the region of RPE changes, and delay in choroidal filling suggest that the primary pathology is associated with choroidal vascular disturbance. However, the exact pathophysiological mechanisms of the disease are not fully known.  Pakikoroid-related diseases include pachychoroid pigment epitheliopathy, central serous chorioretinopathy, pachychoroid neovasculopathy, polypoidal choroidal vasculopathy, focal choroidal excavation, and peripapillary pachychoroid syndrome. These diseases are thought to be reveal different manifestations of common pathological mechanisms. This review highlights the current understanding of genetics, risk factors, and pathogenesis in the spectrum of pachychoroid disease based on the current literature.

Risk Factors for Second Eye Involvement in Eyes with Unilateral Polypoidal Choroidal Vasculopathy

2015 ◽  
Vol 37 (2) ◽  
pp. 177-182 ◽  
Author(s):  
Yasushi Tateno ◽  
Yoichi Sakurada ◽  
Seigo Yoneyama ◽  
Wataru Kikushima ◽  
Fumihiko Mabuchi ◽  
...  
Keyword(s):  
Risk Factors ◽  
Polypoidal Choroidal Vasculopathy ◽  
Eye Involvement ◽  
Choroidal Vasculopathy

Focal Choroidal Excavation Associated With Polypoidal Choroidal Vasculopathy

2013 ◽  
Vol 44 (4) ◽  
pp. 409-411 ◽  
Author(s):  
Emil Anthony T. Say ◽  
Pooja D. Jani ◽  
Matthew F. Appenzeller ◽  
Odette M. Houghton
Keyword(s):  
Polypoidal Choroidal Vasculopathy ◽  
Focal Choroidal Excavation ◽  
Choroidal Vasculopathy
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