Other Viral Uveitis Except for Herpes, Cytomegalovirus and Human Immunodeficiency Viruses

2019 ◽  
pp. 277-282
Keyword(s):  
Visual Acuity ◽  
Epstein Barr Virus ◽  
Ebola Virus ◽  
Viral Disease ◽  
Eye Disease ◽  
Ocular Complications ◽  
Barr Virus ◽  
Human Immunodeficiency Viruses ◽  
Epstein Barr ◽  
Rift Valley Virus

Viral uveitis may happen as isolated eye disease or as a part of systemic viral disease. Large ocular findings occur. Early diagnosis and treatment are important to prevent ocular complications that are threatened by visual acuity. In this review, we mention about other viral üveitis seen less frequently except for herpes, cytomegalovirus, and human immunodeficiency viruses including Epstein-Barr virus (EBV), measles (Rubeola), rubella (Rubella), arboviruses (Dang, Chikungunya, Rift Valley virus and West Nile virus [WNV]) and other rare causes Influenza, Koksaki, Ebola virus.

Epstein–Barr virus retinitis in an immunocompromised child: A case report

2020 ◽  
pp. 112067212092685
Author(s):  
Hung-Da Chou ◽  
Wee Min Teh ◽  
Ming-Hui Sun ◽  
Kuan-Jen Chen
Keyword(s):  
Visual Acuity ◽  
Epstein Barr Virus ◽  
Treatment Options ◽  
Acute Retinal Necrosis ◽  
Varicella Zoster ◽  
Barr Virus ◽  
Immunocompromised Child ◽  
Epstein Barr ◽  
Poor Outcomes ◽  
Simplex Virus

Introduction The Epstein–Barr virus is a rare causative pathogen identified in the posterior segment. The majority of cases were presented with a serious condition of acute retinal necrosis, and most of these eyes had poor outcomes. The clinical features and effective treatment options for this condition are still unclear. Case description: A 10-year-old boy with leukaemia and receiving immunosuppressive regimen presented with decreasing visual acuity to counting fingers in his left eye for 2 weeks. Fundus examination revealed disc swelling, retinitis, retinal exudates and haemorrhages. Aqueous polymerase chain reaction was positive for Epstein–Barr virus DNA but negative for cytomegalovirus, herpes simplex virus and varicella zoster virus DNA. Systemic acyclovir and intravitreal ganciclovir injection were administered. Seven months later, retinitis resolved with remnant retinal fibrosis, and visual acuity improved to 20/500. Conclusion Epstein–Barr virus is rarely identified as a sole pathogen in retinitis. Peripapillary predilection might be another type of presenting feature apart from the more-commonly reported peripheral acute retinal necrosis.

scholarly journals Retinal vasculitis associated with Epstein-Barr virus infection in a young immunocompetent patient. First Colombian case report

Case reports ◽  
2019 ◽  
Vol 5 (2) ◽  
pp. 139-146
Author(s):  
Santiago Sánchez-Pardo ◽  
Julia Recalde-Reyes ◽  
Juan Pablo Osorio-Lombana
Keyword(s):  
Visual Acuity ◽  
Epstein Barr Virus ◽  
Case Reports ◽  
Retinal Vasculitis ◽  
Diagnostic Algorithm ◽  
Immunocompetent Patient ◽  
Epstein Barr Virus Infection ◽  
Barr Virus ◽  
Eye Involvement ◽  
Epstein Barr

Introduction: Epstein - Barr virus (EBV) infection is usually asymptomatic and persists throughout life. Eye involvement is rare, and even though there are some case reports, none of them comes from Colombia or Latin America.Case presentation: Immunocompetent young man with generalized unilateral retinal vasculitis, temporal and inferonasal bloodless vessels in the periphery, intraretinal hemorrhages, intense vitritis and retinal detachment. Epstein-Barr virus presence was determined using a polymerase chain reaction technique in vitreous humor. The patient recovered visual acuity with conventional antiviral oral treatment.Discussion: Eye involvement associated with Epstein-Barr virus is observed in immunocom­promised patients, especially with HIV infection, where retinal involvement may occur. This case reports the presence of this pathology in an immunocompetent patient.Conclusions: Retinal vasculitis is a rare entity, frequently associated with immunocompromise. There is no diagnostic algorithm for this disease and eye involvement may be variable; there are no standard lines of treatment either. The evidence reported here explains the need for studies in selected patients showing visual acuity involve­ment without an established etiology.

Lack of Epstein-Barr virus- and HIV-specific CD27− CD8+ T cells is associated with progression to viral disease in HIV-infection

AIDS ◽  
2002 ◽  
Vol 16 (15) ◽  
pp. 2001-2011 ◽  
Author(s):  
Debbie van Baarle ◽  
Stefan Kostense ◽  
Egbert Hovenkamp ◽  
Graham Ogg ◽  
Nening Nanlohy ◽  
...  
Keyword(s):  
T Cells ◽  
Hiv Infection ◽  
Cd8 T Cells ◽  
Epstein Barr Virus ◽  
Viral Disease ◽  
Barr Virus ◽  
Epstein Barr

A Quantitative Ultrastructural Study of Peripheral Blood Lymphocytes Containing Parallel Tubular Arrays in Epstein-Barr Virus and Cytomegalo-Virus Mononucleosis

1981 ◽  
Vol 39 ◽  
pp. 454-455
Author(s):  
C. M. Payne ◽  
P. M. Tennican
Keyword(s):  
Peripheral Blood ◽  
Lymphocyte Count ◽  
Epstein Barr Virus ◽  
Absolute Lymphocyte Count ◽  
Peripheral Blood Lymphocytes ◽  
Clinical State ◽  
Barr Virus ◽  
The Absolute ◽  
Epstein Barr ◽  
Tubular Arrays

In the normal peripheral circulation there exists a sub-population of lymphocytes which is ultrastructurally distinct. This lymphocyte is identified under the electron microscope by the presence of cytoplasmic microtubular-like inclusions called parallel tubular arrays (PTA) (Figure 1), and contains Fc-receptors for cytophilic antibody. In this study, lymphocytes containing PTA (PTA-lymphocytes) were quantitated from serial peripheral blood specimens obtained from two patients with Epstein -Barr Virus mononucleosis and two patients with cytomegalovirus mononucleosis. This data was then correlated with the clinical state of the patient.It was determined that both the percentage and absolute number of PTA- lymphocytes was highest during the acute phase of the illness. In follow-up specimens, three of the four patients' absolute lymphocyte count fell to within normal limits before the absolute PTA-lymphocyte count.In one patient who was followed for almost a year, the absolute PTA- lymphocyte count was consistently elevated (Figure 2). The estimation of absolute PTA-lymphocyte counts was determined to be valid after a morphometric analysis of the cellular areas occupied by PTA during the acute and convalescent phases of the disease revealed no statistical differences.

Studies of Epstein-Barr Virus Antigens Using Immunoperoxidase and Immunofluorescence Techniques

1975 ◽  
Vol 33 ◽  
pp. 342-343
Author(s):  
R. Stephens ◽  
K. Traul ◽  
D. Woolf ◽  
P. Gaudreau
Keyword(s):  
Electron Microscopy ◽  
Nasopharyngeal Carcinoma ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
If Technique ◽  
Infected Cells ◽  
Virus Antigens ◽  
Epstein Barr ◽  
Virus Capsid Antigen ◽  
Antigen Reactivity

A number of antigens have been found associated with persistent EBV infections of lymphoblastoid cells. Identification and localization of these antigens were principally by immunofluorescence (IF) techniques using sera from patients with nasopharyngeal carcinoma (NPC), Burkitt lymphoma (BL), and infectious mononucleosis (IM). Our study was mainly with three of the EBV related antigens, a) virus capsid antigen (VCA), b) membrane antigen (MA), and c) early antigens (EA) using immunoperoxidase (IP) techniques with electron microscopy (EM) to elucidate the sites of reactivity with EBV and EBV infected cells.Prior to labeling with horseradish peroxidase (HRP), sera from NPC, IM, and BL cases were characterized for various reactivities by the indirect IF technique. Modifications of the direct IP procedure described by Shabo and the indirect IP procedure of Leduc were made to enhance penetration of the cells and preservation of antigen reactivity.

Quantitative analysis of circulating cell-free Epstein-Barr virus (EBV) DNA levels in patients with EBV-associated lymphoid malignancies

2000 ◽  
Vol 111 (1) ◽  
pp. 239-246 ◽  
Author(s):  
Kenny I. K. Lei ◽  
Lisa Y.S. Chan ◽  
Wing Y. Chan ◽  
Philip J. Johnson ◽  
Y. M. Dennis Lo
Keyword(s):  
Quantitative Analysis ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Lymphoid Malignancies ◽  
Ebv Dna ◽  
Epstein Barr

Chronic bullous disease of childhood following Epstein-Barr virus seroconversion: a case report

1996 ◽  
Vol 21 (2) ◽  
pp. 123-126
Author(s):  
U. BALDARI ◽  
A. ASCARI RACCAGNI ◽  
B. CELLI ◽  
M. GIOVANNA RIGHINI
Keyword(s):  
Case Report ◽  
Epstein Barr Virus ◽  
Barr Virus ◽  
Bullous Disease ◽  
Epstein Barr
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