Adaptive Optics in Retinal Imaging

Adaptive Optics (AO) is a new instrument that provides high-resolution imaging of retinal microstructures by correcting the aberrations. AO has been used to integrate with the different retinal imaging systems such as fundus camera, scanning laser ophthalmoscopy, fundus angiography, and optic coherence tomography. As a result, retinal images with nearly diffraction-limited resolution that allows the exploration of the cellular details of the retina. AO is still at the early stages of ophthalmology and has some limitations. However recent times there are a lot of studies evaluating the clinical applications and advantages of AO. These studies indicate that AO will begin to be used more widely in retina clinics in the near future.

PLoS ONE ◽  
2016 ◽  
Vol 11 (4) ◽  
pp. e0152788 ◽  
Author(s):  
Mohamed Kamel Soliman ◽  
Mohammad Ali Sadiq ◽  
Aniruddha Agarwal ◽  
Salman Sarwar ◽  
Muhammad Hassan ◽  
...  

2013 ◽  
Vol 155 (5) ◽  
pp. 870-881.e3 ◽  
Author(s):  
Kohei Takayama ◽  
Sotaro Ooto ◽  
Masanori Hangai ◽  
Naoko Ueda-Arakawa ◽  
Sachiko Yoshida ◽  
...  

Ophthalmology ◽  
2011 ◽  
Vol 118 (5) ◽  
pp. 873-881 ◽  
Author(s):  
Sotaro Ooto ◽  
Masanori Hangai ◽  
Kohei Takayama ◽  
Atsushi Sakamoto ◽  
Akitaka Tsujikawa ◽  
...  

2016 ◽  
Vol 6 (1) ◽  
Author(s):  
Muneo Yamaguchi ◽  
Shintaro Nakao ◽  
Yoshihiro Kaizu ◽  
Yoshiyuki Kobayashi ◽  
Takahito Nakama ◽  
...  

Abstract Histological studies from autopsy specimens have characterized hard exudates as a composition of lipid-laden macrophages or noncellular materials including lipid and proteinaceous substances (hyaline substances). However, the characteristics of hard exudates in living patients have not been examined due to insufficient resolution of existing equipment. In this study, we used adaptive optics scanning laser ophthalmoscopy (AO-SLO) to examine the characteristics of hard exudates in patients with retinal vascular diseases. High resolution imaging using AO-SLO enables morphological classification of retinal hard exudates into two types, which could not be distinguished either on fundus examination or by spectral domain optical coherence tomography (SD-OCT). One, termed a round type, consisted of an accumulation of spherical particles (average diameter of particles: 26.9 ± 4.4 μm). The other, termed an irregular type, comprised an irregularly shaped hyper-reflective deposition. The retinal thickness in regions with round hard exudates was significantly greater than the thickness in regions with irregular hard exudates (P = 0.02). This differentiation of retinal hard exudates in patients by AO-SLO may help in understanding the pathogenesis and clinical prognosis of retinal vascular diseases.


Ophthalmology ◽  
2010 ◽  
Vol 117 (9) ◽  
pp. 1800-1809.e2 ◽  
Author(s):  
Sotaro Ooto ◽  
Masanori Hangai ◽  
Atsushi Sakamoto ◽  
Akitaka Tsujikawa ◽  
Kenji Yamashiro ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document