scholarly journals Single Afferent Nerve Fibers in the Spinal Dorsal Roots Activated by Manual Acupuncture Needle Stimulation in Frog's Hind Limbs.

2001 ◽  
Vol 51 (1) ◽  
pp. 91-97
Author(s):  
Hiroko IKEDA ◽  
Sae UCHIDA ◽  
Mayura SHIMURA ◽  
Atsuko SUZUKI ◽  
Yoshihiro AIKAWA
Keyword(s):  
Nerve Fibers ◽  
Afferent Nerve ◽  
Manual Acupuncture ◽  
Acupuncture Needle ◽  
Spinal Dorsal ◽  
Dorsal Roots ◽  
Hind Limbs ◽  
Afferent Nerve Fibers ◽  
Needle Stimulation

Spontaneous action potential generation due to persistent sodium channel currents in simulated carotid body afferent fibers

2008 ◽  
Vol 104 (5) ◽  
pp. 1394-1401 ◽  
Author(s):  
David F. Donnelly
Keyword(s):  
Carotid Body ◽  
High Sensitivity ◽  
Nerve Fibers ◽  
Afferent Nerve ◽  
Random Pattern ◽  
Nerve Terminals ◽  
Discharge Rates ◽  
Afferent Nerve Fibers ◽  
Axonal Diameter ◽  
Spontaneous Action

The mechanism by which action potentials (APs) are generated in afferent nerve fibers in the carotid body is unknown, but it is generally speculated to be release of an excitatory transmitter and synaptic depolarizing events. However, previous results suggested that Na+ channels in the afferent nerve fibers play an important role in this process. To better understand the potential mechanism by which Na+ channels may generate APs, a mathematical model of chemoreceptor nerve fibers that incorporated Hodgkin-Huxley-type Na+ channels with kinetics of activation and inactivation, as determined previously from recordings of petrosal chemoreceptor neurons, was constructed. While the density of Na+ channels was kept constant, spontaneous APs arose in nerve terminals as the axonal diameter was reduced to that in rat carotid body. AP excitability and pattern were similar to those observed in chemoreceptor recordings: 1) a random pattern at low- and high-frequency discharge rates, 2) a high sensitivity to reductions in extracellular Na+ concentration, and 3) a variation in excitability that increased with AP generation rate. Taken together, the results suggest that an endogenous process in chemoreceptor nerve terminals may underlie AP generation, a process independent of synaptic depolarizing events.

scholarly journals Dystrophin is expressed in smooth muscle and afferent nerve fibers in the rat urinary bladder

2019 ◽  
Vol 60 (2) ◽  
pp. 202-210 ◽  
Author(s):  
Judith M. Lionarons ◽  
Govert Hoogland ◽  
Ruben G. F. Hendriksen ◽  
Catharina G. Faber ◽  
Danique M. J. Hellebrekers ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Urinary Bladder ◽  
Nerve Fibers ◽  
Afferent Nerve ◽  
Rat Urinary Bladder ◽  
Afferent Nerve Fibers
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