Temporal Processing Abilities across Different Age Groups

2011 ◽  
Vol 22 (01) ◽  
pp. 005-012 ◽  
Author(s):  
Ajith Kumar U ◽  
A.V. Sangamanatha
Keyword(s):  
Temporal Processing ◽  
Age Groups ◽  
Duration Discrimination ◽  
Elderly Persons ◽  
Research Subjects ◽  
Cross Sectional ◽  
Age Related ◽  
Fourth Decade ◽  
Processing Abilities ◽  
Effects Of Aging

Background: Psychophysical evidence indicates age-related decline over a broad range of auditory abilities. Thus, age-related deterioration in temporal processing abilities also may be expected. At issue is whether the various dimensions of temporal processing decline at the same or at different rates across age. Purpose: To determine whether various temporal processes decline with aging and whether some are more resistant to the effects of aging than others. Study Sample: A total of 176 subjects in the age range from 20 to 85 yr participated in this research. Subjects were divided into six cross-sectional age groups. There were 30 subjects per age decade up to 70 yr and 26 subjects in the age group >70 yr. Data Collection and Analysis: Temporal processing was evaluated using gap detection, duration discrimination, modulation detection, and duration pattern. Results: Individuals in the 20–30 and 30–40 yr groups performed significantly better in all the psychoacoustic measures in comparison to other age groups. Deterioration in temporal processing began after the fourth decade of life. Deterioration accelerated after 70 yr of age. Conclusions: There is a systematic, age-related decline in temporal processing starting from the fourth decade of life. The deficits in temporal processing observed in the present study may be related in part to the difficulties that elderly persons encounter in noisy listening situations.

Temporal Factors and Speech Recognition Performance in Young and Elderly Listeners

1993 ◽  
Vol 36 (6) ◽  
pp. 1276-1285 ◽  
Author(s):  
Sandra Gordon-Salant ◽  
Peter J. Fitzgibbons
Keyword(s):  
Speech Recognition ◽  
Temporal Processing ◽  
Recognition Performance ◽  
Duration Discrimination ◽  
Related Factors ◽  
Auditory Temporal Processing ◽  
Percent Correct ◽  
Hearing Sensitivity ◽  
Age Related ◽  
Processing Abilities

This study investigated factors that contribute to deficits of elderly listeners in recognizing speech that is degraded by temporal waveform distortion. Young and elderly listeners with normal hearing sensitivity and with mild-to-moderate, sloping sensorineural hearing losses were evaluated. Low-predictability (LP) sentences from the Revised Speech Perception in Noise test (R-SPIN) (Bilger, Nuetzel, Rabinowitz, & Rzeczkowski, 1984) were presented to subjects in undistorted form and in three forms of distortion: time compression, reverberation, and interruption. Percent-correct recognition scores indicated that age and hearing impairment contributed independently to deficits in recognizing all forms of temporally distorted speech. In addition, subjects’ auditory temporal processing abilities were assessed on duration discrimination and gap detection tasks. Canonical correlation procedures showed that some of the suprathreshold temporal processing measures, especially gap duration discrimination, contributed to the ability to recognize reverberant speech. The overall conclusion is that age-related factors other than peripheral hearing loss contribute to diminished speech recognition performance of elderly listeners.

scholarly journals Changes in the intracranial volume from early adulthood to the sixth decade of life: A longitudinal study

2019 ◽  
Author(s):  
Yaron Caspi ◽  
Rachel M. Brouwer ◽  
Hugo G. Schnack ◽  
Marieke E. van de Nieuwenhuijzen ◽  
Wiepke Cahn ◽  
...  
Keyword(s):  
Mixed Model ◽  
Linear Mixed Model ◽  
Brain Aging ◽  
Age Groups ◽  
Direct Calculation ◽  
Normal Brain ◽  
Intracranial Volume ◽  
Cross Sectional ◽  
Age Related ◽  
Fourth Decade

AbstractNormal brain-aging occurs at all structural levels. Excessive pathophysiological changes in the brain, beyond the normal one, are implicated in the etiology of brain disorders such as severe forms of the schizophrenia spectrum and dementia. To account for brain-aging in health and disease, it is critical to study the age-dependent trajectories of brain biomarkers at various levels and among different age groups.The intracranial volume (ICV) is a key biological marker, and changes in the ICV during the lifespan can teach us about the biology of development, aging, and gene X environment interactions. However, whether ICV changes with age in adulthood is not resolved.Applying a semi-automatic in-house-built algorithm for ICV extraction on T1w MR brain scans in the Dutch longitudinal cohort (GROUP), we measured ICV changes. Individuals between the ages of 16 and 55 years were scanned up to three consecutive times with 3.32±0.32 years between consecutive scans (N=482, 359, 302). Using the extracted ICVs, we calculated ICV longitudinal aging-trajectories based on three analysis methods; direct calculation of ICV differences between the first and the last scan, fitting all ICV measurements of individuals to a straight line and applying a global linear mixed model fitting. We report statistically significant increases in the ICV in adulthood until the fourth decade of life (average change +0.03%/y, or about 0.5 ml/y, at age 20), and decreases in the ICV afterward (−0.09%/y, or about −1.2 ml/y, at age 55). To account for previous cross-sectional reports of ICV changes, we analyzed the same data using a cross-sectional approach. Our cross-sectional analysis detected ICV changes consistent with the previously reported cross-sectional effect. However, the reported amount of cross-sectional changes within this age range was significantly larger than the longitudinal changes. We attribute the cross-sectional results to a generational effect.In conclusion, the human intracranial volume does not stay constant during adulthood but instead shows a small increase during young adulthood and a decrease thereafter from the fourth decade of life. The age-related changes in the longitudinal setup are smaller than those reported using cross-sectional approaches and unlikely to affect structural brain imaging studies correcting for intracranial volume considerably. As to the possible mechanisms involved, this awaits further study, although thickening of the meninges and skull bones have been proposed, as well as a smaller amount of brain fluids addition above the overall loss of brain tissue.

Age related volume of cadaver-prostates in Bangladesh

1970 ◽  
Vol 4 (2) ◽  
pp. 74-77
Author(s):  
Rukshana Ahmed ◽  
Shamim Ara
Keyword(s):  
Prostate Gland ◽  
Age Groups ◽  
Clinical Settings ◽  
Cross Sectional ◽  
Medical College ◽  
Age Related ◽  
Group A ◽  
Key Words Prostate ◽  
The Mean ◽  
Group B

Pathological changes in the prostate gland occur commonly with advancing age including inflammation, atrophy, hyperplasia and carcinoma and a change in volume is also evident. Estimation of volume of prostate may be useful in a variety of clinical settings. A cross-sectional descriptive study was designed to see the changes in volume of the prostate with advancing age and done in the Department of Anatomy, Dhaka Medical College, Dhaka from August 2006 to June 2007. The study was performed on 70 post-mortem human prostates collected from the unclaimed dead bodies that were under examination in the Department of Forensic Medicine, Dhaka Medical College, Dhaka. The samples were divided into three age groups; group A (10-20 years), group B (21-40 years) and group C (41-70 years). Volume of the sample was measured by using the ellipsoid formula. The mean ± SD volume of prostate was 7.68 ± 3.64 cm3 in group A, 10.61 ± 3.99 cm3 in group B and 15.40 ± 6.31 cm3 in group C. Mean difference in volume between group A and group C, group B and group C were statistically significant (p<0.001). Statistically significant positive correlation was found between age and volume of prostate (r = + 0.579, p < 0.001). Key Words: Prostate; volume; Bangladeshi. DOI: 10.3329/imcj.v4i2.6501Ibrahim Med. Coll. J. 2010; 4(2): 74-77

scholarly journals Age-related decline in the taurine content of the skin in rodents

Amino Acids ◽  
2021 ◽  
Author(s):  
Tomohisa Yoshimura ◽  
Yuki Inokuchi ◽  
Chikako Mutou ◽  
Takanobu Sakurai ◽  
Tohru Nagahama ◽  
...  
Keyword(s):  
High Performance ◽  
Age Groups ◽  
Immunohistochemical Analysis ◽  
Sprague Dawley ◽  
Taurine Supplementation ◽  
Hairless Mice ◽  
Age Related ◽  
Sprague Dawley Rats ◽  
High Concentrations ◽  
Effects Of Aging

AbstractTaurine, a sulfur-containing amino acid, occurs at high concentrations in the skin, and plays a role in maintaining the homeostasis of the skin. We investigated the effects of aging on the content and localization of taurine in the skin of mice and rats. Taurine was extracted from the skin samples of hairless mice and Sprague Dawley rats, and the taurine content of the skin was determined by high-performance liquid chromatography (HPLC). The results of the investigation revealed that the taurine content in both the dermis and epidermis of hairless mice declined significantly with age. Similar age-related decline in the skin taurine content was also observed in rats. In contrast, the taurine content in the sole remained unchanged with age. An immunohistochemical analysis also revealed a decreased skin taurine content in aged animals compared with younger animals, although no significant differences in the localization of taurine were observed between the two age groups. Supplementation of the drinking water of aged mice with 3% (w/v) taurine for 4 weeks increased the taurine content of the epidermis, but not the dermis. The present study showed for the first time that the taurine content of the skin decreased with age in mice and rats, which may be related to the impairment of the skin homeostasis observed with aging. The decreased taurine content of the epidermis in aged animals was able to be rescued by taurine supplementation.

scholarly journals Gene Expression Profile in Different Age Groups and Its Association with Cognitive Function in Healthy Malay Adults in Malaysia

Cells ◽  
2021 ◽  
Vol 10 (7) ◽  
pp. 1611
Author(s):  
Nur Fathiah Abdul Abdul Sani ◽  
Ahmad Imran Zaydi Amir Amir Hamzah ◽  
Zulzikry Hafiz Abu Abu Bakar ◽  
Yasmin Anum Mohd Mohd Yusof ◽  
Suzana Makpol ◽  
...  
Keyword(s):  
Gene Expression ◽  
Cognitive Decline ◽  
Cognitive Aging ◽  
Successful Aging ◽  
Expression Patterns ◽  
Age Groups ◽  
Genetic Network ◽  
Cross Sectional ◽  
Age Related ◽  
Age Related Cognitive Decline

The mechanism of cognitive aging at the molecular level is complex and not well understood. Growing evidence suggests that cognitive differences might also be caused by ethnicity. Thus, this study aims to determine the gene expression changes associated with age-related cognitive decline among Malay adults in Malaysia. A cross-sectional study was conducted on 160 healthy Malay subjects, aged between 28 and 79, and recruited around Selangor and Klang Valley, Malaysia. Gene expression analysis was performed using a HumanHT-12v4.0 Expression BeadChip microarray kit. The top 20 differentially expressed genes at p < 0.05 and fold change (FC) = 1.2 showed that PAFAH1B3, HIST1H1E, KCNA3, TM7SF2, RGS1, and TGFBRAP1 were regulated with increased age. The gene set analysis suggests that the Malay adult’s susceptibility to developing age-related cognitive decline might be due to the changes in gene expression patterns associated with inflammation, signal transduction, and metabolic pathway in the genetic network. It may, perhaps, have important implications for finding a biomarker for cognitive decline and offer molecular targets to achieve successful aging, mainly in the Malay population in Malaysia.

Abstract P127: Gender and Fitness Status Influence Age-related Decline in Peak Heart Rate Achievement: Insight From the FIT Cohort

Circulation ◽  
2016 ◽  
Vol 133 (suppl_1) ◽  
Author(s):  
Haitham Ahmed ◽  
Di Zhao ◽  
Eliseo Guallar ◽  
Michael J Blaha ◽  
Clinton A Brawner ◽  
...  
Keyword(s):  
Heart Rate ◽  
Age Groups ◽  
Peak Heart Rate ◽  
Cross Sectional ◽  
Fitness Level ◽  
Age Related ◽  
Henry Ford ◽  
Exercise Treadmill ◽  
History Of ◽  
Separate Regression

Background: The declines in peak heart rate (HR) and fitness level with age are related; however, whether this association differs based on gender is not well appreciated. In a large cross-sectional cohort of women and men referred for a clinically indicated exercise treadmill test (ETT), we set out to determine whether the decrease in peak HR by age varied by gender (and fitness) in the Henry Ford Exercise Testing (FIT) project. Methods: We analyzed data on 38,196 apparently-healthy patients aged 18-96 [mean age 51 ± 12 yrs, 25% black, 48% women] who completed an ETT. Those with history of coronary heart disease, congestive heart failure, diabetes on medications, atrial fibrillation or flutter, or taking AV nodal blocking medications were excluded. Being “fit” was defined as achieving ≥ the median MET level for each sex/age-decile group. Peak HR vs age was plotted, and regression lines were used to determine the intercept and slope for each group. Results: Men had higher peak HR than women but with a greater decline over time; the respective intercepts and slopes for peak HR estimates were 202.9 and 0.90 for men and 197.3 and 0.80 for women, (p-interaction = 0.023). Fit people also started out with higher peak HR but approached unfit people at higher age groups; respective intercept and slope by fitness status were 203.0 and 0.87 for fit and 194.7 and 0.83 for unfit (p-interaction <0.001). Separate regression lines were generated for categories of fit men/unfit men, fit women/unfit women ( Figure ). Fit and unfit men had similar declines in peak HR with increasing age (slope=0.92); whereas fit women (slope=0.81) had a slightly greater decline in peak HR with increasing age than unfit women (slope=0.73). However, peak absolute HR for fit people still remains higher than for unfit people even into elderly ages. Conclusion: In this cross-sectional cohort of patients referred for a clinical ETT, we found that the age-related decline in peak HR is influenced by both gender and fitness status.

scholarly journals Histomorphometric Study of Axillary Lymph Nodes in Different Age Groups

2019 ◽  
Vol 08 (04) ◽  
pp. 136-141
Author(s):  
Kafeel Hussain A. ◽  
Shaweez Fathima S. ◽  
V. Sathialakshmi
Keyword(s):  
Lymph Node ◽  
Lymph Nodes ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Germinal Centers ◽  
Axillary Lymph Nodes ◽  
Strong Impact ◽  
Axillary Lymph ◽  
Cross Sectional ◽  
Age Related

Abstract Background Although some age-related changes in lymph node histoarchitecture have been described, they are seldom taken into account in traditional depictions of lymph nodes. Recently introduced clinical procedures, such as intranodal vaccinations have demonstrated the need for an accurate knowledge of the degenerative processes of lymph nodes. It is thus deemed necessary to obtain a detailed insight into anatomical changes within the lymph node throughout life as age-related degeneration can have a strong impact on the outcome of these new therapeutic strategies. Aim To study the size and shape of the lymph nodes and to establish the age-dependent histoarchitectural changes in the lymph nodes in different age groups. Materials and Methods A cross-sectional study was conducted in a total of 35 axillary lymph nodes. The adult axillary group of lymph nodes were from subjects aged between 18 and 70 years. The fetal lymph nodes were collected from 8 stillborn fetuses between 37 and 42 weeks. Thickness of the cortex and diameter of the germinal centers were measured using ocular and stage micrometer. Results None of the fetal lymphocytic follicles showed evidence of a prominent germinal center. The germinal centers of young adults were not only more numerous but also larger in size when compared with the old. An age-related involution of the paracortical region was witnessed in the axillary lymph nodes. No evidence of lipomatous atrophy was encountered in any of the fetal lymph nodes. Interesting evidence of it was encountered in younger age groups. However, this was the most prominent feature in the older groups.

scholarly journals The Pattern of Ocular Morbidity, Findings from a Study Conducted in Western Remote Hilly Region of Nepal

1970 ◽  
Vol 1 (1) ◽  
pp. 35-38 ◽  
Author(s):  
P Bastola
Keyword(s):  
Refractive Error ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Ocular Allergy ◽  
Medical Sciences ◽  
Cross Sectional ◽  
Dry Eyes ◽  
Age Related ◽  
Hilly Region ◽  
Ocular Morbidity

Background: There is a lack of study in the pattern of ocular morbidity in western hilly region of Nepal. Therefore a study was carried out to find out the pattern of ocular morbidity, in various age groups in a diagnostic, screening and treatment camp (DST) held in a western hilly remote region of Nepal. Methods: A descriptive, cross sectional study was done to find out the pattern of ocular morbidity in a western hilly region of Nepal. All the cases included in the study were examined thoroughly from Ophthalmological perspective and a diagnosis was made. Patients needing treatment both medical as well as surgical were advised accordingly and referred when indicated. Results: A total of 712 eyes of 356 cases were examined in this study. The range of the age varied from two months of life to 91 yrs of age. Age wise most number of cases were in the school going age group accounting for almost 80% of all the cases. The commonest ocular morbidity encountered were refractive error (15.4%), dry eyes, ocular allergy, followed by cataract. Majority of the cases had both dry eyes and ocular allergy. While 70 eyes of 35 patients had no ocular morbidity. Conclusion: The lower prevalence of age related cataract was due to the extensive cataract surgical coverage provided in the region by various organizations and because of lesser number of cases examined above the age of 40 years. Finding of just three cases of Xerophthalmia (X2B), pointed out towards the success of extensive Vitamin A supplement program run by the ministry of health. Keywords: Refractive error; dry eyes; ocular allergy; cataract DOI: http://dx.doi.org/10.3126/njms.v1i1.5795   Nepal Journal of Medical Sciences. 2012; 1(1): 35-38

scholarly journals Are masters athletic performances predictive of human aging in men and women?

2019 ◽  
pp. 5-12 ◽  
Author(s):  
Jonathon W. Senefeld ◽  
Sandra K. Hunter
Keyword(s):  
Physical Activity ◽  
Athletic Performance ◽  
Age Groups ◽  
Biological Aging ◽  
Human Aging ◽  
Healthy Human ◽  
Cross Sectional ◽  
Very Old ◽  
Age Related ◽  
Human Function

Human aging particularly after ∼70 years, is associated with declines in physical function and athletic performance, that are accelerated in part by age-associated declines in physical activity and exercise training. Because elite athletes maintain high levels of physical activity across the lifespan, older athletes (Masters) may present as a proxy for healthy human aging. Although longitudinal studies are most informative about human aging, there are substantial practical challenges to conducting longitudinally designed research. Masters athletic records and comparisons of performance across age groups can serve as a practical and unique probe to predict the trajectory of human function throughout the lifespan. While useful, the cross-sectional comparison of elite athletic performance across different age groups, however, has inherent limitations in predicting healthy human aging, particularly among women. This review presents evidence that (1) there is a progressive age-related decline in world class performances in freestyle swim swimming, marathon, and triathlon, that accelerates into very old age (∼70 years), and (2) lower participation rates of women relative to men results in an overestimation of the age-related decline in athletic performance particularly in very old women. Thus, while useful, there are some limitations to predicting biological aging among women using current Masters Athletic performances.

A cross-sectional study on foot loading patterns in elite soccer players of different ages

2020 ◽  
Vol 33 (6) ◽  
pp. 939-946
Author(s):  
Thilo Hotfiel ◽  
Tobias Golditz ◽  
Jessy Wegner ◽  
Johannes Pauser ◽  
Matthias Brem ◽  
...  
Keyword(s):  
Plantar Pressure ◽  
Age Groups ◽  
Relative Increase ◽  
Stress Fractures ◽  
Soccer Players ◽  
Cross Sectional ◽  
Pressure Distributions ◽  
Age Related ◽  
Loading Patterns ◽  
Foot Loading

BACKGROUND: Alterations in plantar loading patterns are risk factors for stress injuries of the lower limb, particularly of the foot and ankle. Epidemiological studies have revealed a higher incidence of soccer-related stress fractures of the fifth metatarsal (MT V) in younger athletes than in their adult counterparts. OBJECTIVE: The aim of the present study was to assess the plantar pressure distributions of members of four high-level soccer teams of different age groups to identify age-related differences in loading patterns. METHODS: A total of 65 elite soccer players were included in the study. Data were computed with sensor-loaded insoles (pedar® X system, novel Inc., Munich, Germany) while the players ran in soccer shoes. Plantar pressures for nine defined regions on the preferred and nonpreferred foot were analyzed. RESULTS: The participants consisted of 17 elite male soccer professionals from the first national league (mean 23 years, height 184 cm, weight 81 kg), 14 players from the under-21 squad (U21, 20 years, 180 cm, 75 kg), 15 players from the U17 squad (16 years, 176 cm, 69 kg) and 19 players from the U16 squad (15 years, 179 cm, 70 kg). We detected statistically significantly elevated peak pressures on the lateral aspects of the nonpreferred foot compared with the preferred foot in the U16 and U17 players, corresponding to a relative increase by 29% (p= 0.044) in the lateral midfoot, a relative increase by 24% (p= 0.031) in MT heads 4–5 in the U16 players and a difference of 18% (p= 0.049) in the lateral midfoot in the U17 players. In contrast, the U21 and adult professional players displayed symmetric plantar pressure distributions in all foot regions. CONCLUSIONS: In contrast to adult elite soccer players, adolescents demonstrate asymmetric foot loading patterns with increased peak loads in the lateral aspects of the nonpreferred foot. Our results may provide some explanation for MT V stress fractures that occur in elite adolescents.

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