Ocular Vestibular Evoked Myogenic Potentials: Normative Findings in Children

2018 ◽  
Vol 29 (05) ◽  
pp. 443-450 ◽  
Author(s):  
Jeffery J. Kuhn ◽  
Violette H. Lavender ◽  
Lisa L. Hunter ◽  
Stephanie E. McGuire ◽  
Jareen Meinzen-Derr ◽  
...  
Keyword(s):  
Medical Center ◽  
Tone Burst ◽  
Vestibular Evoked Myogenic Potentials ◽  
Adult Group ◽  
Tertiary Referral ◽  
Stimulus Comparison ◽  
Vestibular Evoked Myogenic Potential ◽  
Tertiary Referral Center ◽  
Adult Participants ◽  
Significant Difference

AbstractTo add to the limited body of literature on ocular vestibular evoked myogenic potential (oVEMP) responses in children and to assess a different montage for oVEMP recording.To evaluate the characteristics of the oVEMP response in children and compare the results with that of a group of healthy adults.Prospective descriptive study from a tertiary referral center.Twenty-two children (mean age = 6.3 yr, standard deviation = ±1.5, range = 3.5–8.9 yr) were recruited from families whose parent(s) were employed by the Cincinnati Children’s Hospital Medical Center (CCHMC). Pediatric participants were categorized by age into three groups for data analysis. The comparison adult group of ten participants were members of the employee staff at CCHMC.Audiometric assessment was completed in all participants. The latency, amplitude, and threshold of the oVEMP responses were recorded using a modified electrode montage with reference at the chin and compared between the pediatric and adult participants.All participants completed testing and had bilateral measurable oVEMP responses using a 105-dB nHL, 500-Hz tone burst stimulus. Comparison between right and left ears across all participants for each oVEMP characteristic found no statistically significant difference. oVEMP testing showed no significant differences with respect to latency, amplitude, interaural amplitude asymmetry, and threshold of response as a function of age.oVEMP responses for ages ≥3 did not differ from responses in adults.

scholarly journals A case series shows independent vestibular labyrinthine function after major surgical trauma to the human cochlea

2021 ◽  
Vol 1 (1) ◽  
Author(s):  
Stefan K. Plontke ◽  
Torsten Rahne ◽  
Ian S. Curthoys ◽  
Bo Håkansson ◽  
Laura Fröhlich
Keyword(s):  
Case Series ◽  
Vestibular Function ◽  
Semicircular Canals ◽  
Vestibular Evoked Myogenic Potentials ◽  
Head Impulse Test ◽  
Surgical Trauma ◽  
Cochlear Function ◽  
Receptor System ◽  
Tertiary Referral Center ◽  
Significant Difference

Abstract Background The receptors for hearing and balance are housed together in the labyrinth of the inner ear and share the same fluids. Surgical damage to either receptor system was widely believed to cause certain permanent loss of the receptor function of the other. That principle, however, has been called into question because there have been anecdotal reports in individual patients of at least partial preservation of cochlear function after major surgical damage to the vestibular division and vice versa. Methods We performed specific objective vestibular function tests before and after surgical trauma (partial or subtotal cochlear removal) for treatment of intracochlear tumors in 27 consecutive patients in a tertiary referral center. Vestibular function was assessed by calorics (low-frequency response of the lateral semicircular canal), vestibulo-ocular reflex by video head impulse test (vHIT) of the three semicircular canals, cervical and ocular vestibular evoked myogenic potentials (cVEMP, saccule and oVEMP, utricle). Preoperative and postoperative distributions were compared with paired t-tests. Results Here we show that there was no significant difference between pre- and post-operative measures for all tests of the five vestibular organs, and that after major surgical cochlear trauma, the vestibular receptors continue to function independently. Conclusions These surprising observations have important implications for our understanding of the function and the surgery of the peripheral auditory and vestibular system in general and open up new possibilities for the development, construction and evaluation of neural interfaces for electrical or optical stimulation of the peripheral auditory and vestibular nervous system.

scholarly journals Prevalence, clinical features and treatment pattern of patients with concurrent diagnoses of rheumatoid arthritis and psoriatic disease: results of a 14-year retrospective study in a tertiary referral center

2019 ◽  
Vol 10 ◽  
pp. 204062231984790
Author(s):  
Kai-Lung Chen ◽  
Hsien-Yi Chiu ◽  
Jui-Hsiang Lin ◽  
Jian-De Ye ◽  
Yi-Hsuan Cho ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Features ◽  
Age Of Onset ◽  
Medical Center ◽  
Skin Lesions ◽  
Tertiary Referral ◽  
Female Ratio ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Psoriatic Disease

Background: Multiple comorbidities, including rheumatoid arthritis (RA), have been reported to be associated with psoriasis. Objective: This study aimed to determine the prevalence and the clinical features of RA among patients with psoriasis in a tertiary referral center. Methods: Between January 2000 and December 2013, all patients coded with psoriatic disease (ICD-9 CM 696.0 OR ICD-9 CM696.1) and RA (ICD-9 CM 714.0) in a tertiary medical center were enrolled. Results: There were 10,844 patients and 9073 patients with psoriatic disease and RA identified by diagnostic codes, respectively. Among patients with psoriasis, 111 patients had claim-based diagnosis of RA (1.02%). By reviewing medical records and telephone interview or clinic visits, 25 of the 111 patients (0.23%) was identified unequivocally as having concurrent RA. Among them, 17 (68%) were female and 16 (64%) patients developed arthritis prior to the onset of psoriasis with a mean lag of 6.3 years (1–19 years); 8 (32%) had psoriasis skin lesions prior to the onset of arthritis with a mean lag of 6.9 years (3–20 years); 1 (4%) had skin lesions and arthritis in the same time; 17 (68%) patients also fulfilled the CASPAR classification criteria for psoriatic arthritis. The mean age of onset for arthritis was 49.6 years old. Conclusions: The prevalence of RA in psoriasis might be overestimated in some previous studies using claimed database. Patients with concurrent RA and psoriasis showed a comparable age of onset and male to female ratio, but had more axial involvements compared to patients without psoriasis.

scholarly journals Ureteric Stent Use - Part of the Solution and Part of the Problem

2017 ◽  
Vol 11 (3) ◽  
pp. 126-130 ◽  
Author(s):  
Victor G. Ilie ◽  
Vlad I. Ilie
Keyword(s):  
Infectious Complications ◽  
Diabetic Patients ◽  
Tertiary Referral ◽  
Tertiary Referral Center ◽  
Chronic Renal Impairment ◽  
Institutional Practice ◽  
Ureteric Stent ◽  
Significant Difference ◽  
Period Data ◽  
Stent Complications

Background: The aim of the study is to comprehensively report on a single tertiary referral center experience with the use of ureteric stents, assess complication burden and determine risk factors to further inform institutional practice. Materials and Methods: The retrospectively analyzed cohorts includes 529 patients treated over a 12 months period. Data regarding details of the index pathology, stent characteristics and complications were collected retrospectively. Results: Most stents (58.9%) were used in the context of stone surgery. Stent encrustation occurred in 14.5% of patients and sepsis in 4.3%. There was a statistically significant difference between the complications of the stents removed after 90 days and the rest of the cohort. Infectious complications were more frequent in diabetic patients and in patients with chronic renal impairment. At our institution, we managed to avoid forgotten stents and catastrophic complications. Conclusion: Stent complications are the complex outcome of interplay between the foreign body and the collecting system environment, influenced by the nature and timing of surgery. Longer stent dwelling times are associated with increased complications rates, especially in patients with significant comorbidities.

Comparison of vestibular evoked myogenic potentials elicited by click and short duration tone burst stimuli

2010 ◽  
Vol 125 (4) ◽  
pp. 343-347 ◽  
Author(s):  
K Kumar ◽  
S Kumar Sinha ◽  
A Kumar Bharti ◽  
A Barman
Keyword(s):  
Short Duration ◽  
Clinical Assessment ◽  
Low Frequency ◽  
Tone Burst ◽  
Normal Hearing ◽  
Vestibular Evoked Myogenic Potentials ◽  
Vestibular Evoked Myogenic Potential ◽  
Acoustic Stimuli ◽  
Myogenic Potential ◽  
Electrical Impulses

AbstractIntroduction:Vestibular evoked myogenic potentials are short latency electrical impulses that are produced in response to higher level acoustic stimuli. They are used clinically to diagnose sacculocollic pathway dysfunction.Aim:This study aimed to compare the vestibular evoked myogenic potential responses elicited by click stimuli and short duration tone burst stimuli, in normal hearing individuals.Method:Seventeen subjects participated. In all subjects, we assessed vestibular evoked myogenic potentials elicited by click and short duration tone burst stimuli.Results and conclusion:The latency of the vestibular evoked myogenic potential responses (i.e. the p13 and n23 peaks) was longer for tone burst stimuli compared with click stimuli. The amplitude of the p13–n23 waveform was greater for tone burst stimuli than click stimuli. Thus, the click stimulus may be preferable for clinical assessment and identification of abnormalities as this stimulus has less variability, while a low frequency tone burst stimulus may be preferable when assessing the presence or absence of vestibular evoked myogenic potential responses.

scholarly journals Vestibular evoked myogenic potential

2014 ◽  
Vol 67 (suppl. 1) ◽  
pp. 38-45
Author(s):  
Slobodanka Lemajic-Komazec ◽  
Zoran Komazec ◽  
Ljiljana Vlaski ◽  
Slobodan Savovic ◽  
Maja Buljcik-Cupic ◽  
...  
Keyword(s):  
Tone Burst ◽  
Acoustic Stimulation ◽  
Vestibular Evoked Myogenic Potentials ◽  
Vestibular Evoked Myogenic Potential ◽  
Average Value ◽  
Myogenic Potential ◽  
The Difference ◽  
Interaural Differences ◽  
The Right ◽  
A Prospective Study

Introduction. Vestibular evoked myogenic potentials are neurophysiological method for examining of saccular function, the bottom of the vestibular nerve that in nervates the sacculus and central vestibular pathways. Those are inhibitory potentials of the sternocleido mastoid musclein response to ipsilateral acoustic stimulation of the sacculus. Parameters of vestibular evoked myogenic potential testing include threshold, latencies of p1 and n1 wave and interamplitude p13-n23, interaural difference of p13 and n23 latency and interaural amplitude difference ratio. The aim of this study was to compire parameters standardization of vestibular evoked myogenic potentials responses, latency p13 and n23 of waves, the amplitude of responses and interaural differences in the amplitude andto determinewhether there is a difference in values between the sexes. Material and methods. This research was meant to be a prospective study which included 30 normal audiovestibular volunteers of both sexes. The group consisted of 53.3% women and 46.7% men. The saccular function testing by vestibular evoked myogenic potentials was performed monoaurally using air-conductive 500 Hz tone burst auditory stimulation. Results. The average value of the p13 wave latency in healthy subjects of this study was 15.18 ms (?1.24) while the mean latency of n23 waves in the same subjects was 25.00 ms (?2.23). The average value of the amplitude of the p13-n23 waves was 80.28 (34. ?04) microvolts. Conclusion. The difference in the values of the basic parameters of vestibular evoked myogenic potential responses between men and women does not exist. No differences between the right and the left ear in the values of latency and amplitude were observed.

scholarly journals Middle Ear Packing and External Ear Packing with Fibrin Glue Enhances the Success of Fat Myringoplasty without Hyaluronic Acid Disc

2021 ◽  
Author(s):  
Jongmin Kim ◽  
Chul Ho Jang
Keyword(s):  
Success Rate ◽  
Fibrin Glue ◽  
Middle Ear ◽  
Fat Graft ◽  
External Ear ◽  
Tertiary Referral ◽  
Closure Rate ◽  
Tertiary Referral Center ◽  
Significant Difference ◽  
The Mean

Background: To date, FM using middle ear packing has rarely reported. In this study, we hypothesized that middle ear packing with dexamethasone soaked gelfoam and fibrin glue over the fat graft could promote the success rate of TMP closure regardless of perforation size. Methods: Between January 2005 and July 2020, a total of 209 patients who underwent fat myringoplasty due to chronic TMP at tertiary referral center were encountered and analyzed. The success rate and audiologic outcome was analyzed. Results: The mean successful TM closure rate was 88.0 %. The success rate by different age generation was not significant difference. The size of the perforation grade showed no significant difference. The perforation site by anterior or posterior was not significant. The preoperative mean threshold of AC, BC and ABG were 55.71, 12.98 and 42.73 dB respectively. The postoperative mean threshold of AC, BC and ABG were 23.67, 12.98 and 10.69 dB. The change of preoperative and postoperative hearing showed statistically significant. Conclusion: From our results, the simple trimming of the perforation edge and middle ear packing with external ear canal packing using fibrin glue induced the stable adhesion between the remnant TM and the fat graft.

Clinical features and management of presumed ocular tuberculosis: A long-term follow-up cohort study in a tertiary referral center in Brazil

2021 ◽  
pp. 112067212110446
Author(s):  
Yuslay Fernández Zamora ◽  
Luciana Peixoto Finamor ◽  
Luci Meire P Silva ◽  
Denise S Rodrigues ◽  
Ricardo P Casaroli-Marano ◽  
...  
Keyword(s):  
Clinical Features ◽  
Oral Prednisone ◽  
Interferon Gamma Release Assay ◽  
Tertiary Referral ◽  
Ocular Tuberculosis ◽  
Tertiary Referral Center ◽  
Referral Center ◽  
Significant Difference ◽  
Presumed Ocular Tuberculosis

Purpose: To evaluate the clinical features and management of presumed ocular tuberculosis (OTB). Method: A prospective 3-year follow-up study of patients with ocular inflammation that performed Interferon-gamma release assay (IGRA) and tuberculin skin test (TST) was conducted in a tertiary referral center in Brazil. Patients with clinical signs highly suspect of OTB with a positive TST and/or IGRA with other causes ruled out were prescribed anti-tuberculosis therapy (ATT) during 9 months. Clinical features and treatment outcomes were recorded. Results: Seventy-two patients (mean age 48.3 ± 15.7 years) were included in the study, and most were female (65.3%, n = 47). Posterior uveitis (43.1%, n = 31) was the main clinical feature. Multifocal choroiditis (25%, n = 18) was the most common choroidal involvement. Concomitant oral prednisone (45.8%, n = 33) during ATT was associated with more recurrences ( p = 0.04). A significant difference ( p < 0.001) between initial and final best-corrected visual acuity after ATT conclusion was observed. Cure or remission was observed in 58 (85.3%) patients that completed follow-up ( n = 68). Conclusion: In our cohort some variation in demographics and ocular phenotypes of presumed OTB was observed. The high rates of cure or remission of our patients strongly support the ATT in presumed OTB. Oral corticosteroids during ATT were associated with higher recurrences rates.

Tone-induced cervical and ocular vestibular-evoked myogenic potentials: comparing abnormalities in traumatic and non-traumatic vestibular disease

2018 ◽  
Vol 132 (10) ◽  
pp. 906-910 ◽  
Author(s):  
N S Longridge ◽  
A I Mallinson
Keyword(s):  
Companion Paper ◽  
High Rate ◽  
Vestibular Evoked Myogenic Potentials ◽  
Tertiary Referral ◽  
Vestibular Evoked Myogenic Potential ◽  
Vestibular Disease ◽  
Myogenic Potential ◽  
Number Of Patients ◽  
History Of ◽  
Vestibular Assessment

AbstractBackgroundOtolithic function is poorly understood, but vestibular-evoked myogenic potential testing has allowed the documentation of pathology in patients who complain of imbalance.MethodsSeventy-four patients with traumatic and non-traumatic vestibular disease were sequentially assessed at a tertiary referral neuro-otology unit in a teaching hospital. A detailed history of all patients was taken and standard vestibular assessment was conducted using the technique described in the companion paper. The results of both groups of patients were analysed and the rate of abnormalities was assessed.ResultsThere was a high rate of abnormalities, including bilateral pathology, in a significant number of patients. Many patients in both groups inexplicably failed to recover.ConclusionVestibular-evoked myogenic potentials are helpful in documenting pathology, including bilateral pathology, which is outlined in the literature as being exceedingly difficult to compensate for.

Short Communication: The Belly–Tendon Derivation Yields Superior Ocular Vestibular Evoked Myogenic Potential Amplitudes in a Normal Pediatric Sample

2020 ◽  
Vol 29 (1) ◽  
pp. 88-93
Author(s):  
Megan Bilodeau ◽  
Gary P. Jacobson ◽  
Richard A. Roberts ◽  
Kelsey Hatton
Keyword(s):  
Observational Study ◽  
Prospective Observational Study ◽  
Short Communication ◽  
Medical Center ◽  
Tertiary Care ◽  
Vestibular Evoked Myogenic Potentials ◽  
Vestibular Evoked Myogenic Potential ◽  
Myogenic Potential ◽  
Tertiary Care Medical Center ◽  
N1 Wave

Purpose The purpose of the investigation was to determine whether the “belly–tendon” electrode derivation produced ocular vestibular evoked myogenic potentials (oVEMPs) in children that were superior to those recorded with the infraorbital–chin electrode derivation. Method This was a prospective observational study using a sample of convenience at a tertiary care medical center. Subjects were 13 children between the ages of 5 and 12 years. We compared the latency of the N1 wave and the N1–P1 peak-to-peak amplitude for the belly–tendon electrode derivation to the infraorbital–chin electrode derivation. Results The belly–tendon electrode derivation was associated with superior N1–P1 amplitudes compared to the infraorbital–chin electrode derivation. However, the large amplitude was also associated with greater variability compared to the infraorbital–chin derivation. There were no significant electrode derivation–based differences in N1 latency. Additionally, there was no predictable relationship between age and oVEMP amplitude. Conclusion As shown previously in adults, the belly–tendon electrode derivation produces significantly larger oVEMP amplitudes compared to the infraorbital–chin electrode derivation.

Vestibular evoked myogenic potentials in patients with fibromyalgia syndrome

2010 ◽  
Vol 124 (6) ◽  
pp. 610-615 ◽  
Author(s):  
Y A Bayazit ◽  
F Celenk ◽  
A G Gunduz ◽  
B Gunduz ◽  
N Ondag ◽  
...  
Keyword(s):  
Fibromyalgia Syndrome ◽  
Vestibular Evoked Myogenic Potentials ◽  
Future Research ◽  
Vestibular Evoked Myogenic Potential ◽  
Objective Indicator ◽  
Statistical Comparison ◽  
Myogenic Potential ◽  
Control Subjects ◽  
Significant Difference ◽  
Interpeak Latency

AbstractObjective:To assess vestibular evoked myogenic potentials in patients with fibromyalgia syndrome.Methods:Twenty-four patients with fibromyalgia syndrome (two men and 22 women) and 21 female controls were included in the study. All patients underwent vestibular evoked myogenic potential testing.Results:Statistical comparison of fibromyalgia patients with control subjects showed a significant difference with respect to n23 latencies and interpeak latencies (p < 0.05). There was no significant difference in p13 latencies, nor in p13 amplitudes, n23 amplitudes or interpeak amplitudes (p > 0.05).Conclusions:Although patients with fibromyalgia syndrome generally have subjective neurotological symptoms, clinical and laboratory assessments usually fail to detect any objective abnormality. However, it is possible to detect abnormalities on vestibular evoked myogenic potential testing in such patients, indicating dysfunction in the vestibulospinal pathway, possibly in the saccule. Elongation of the n23 latency and of the interpeak latency of waves p13–n23, during vestibular evoked myogenic potential testing, may be a useful, objective indicator demonstrating neurotological involvement in fibromyalgia syndrome patients. Future research investigating the mechanisms of this latency elongation may help increase understanding of the pathogenesis of fibromyalgia syndrome.

Sign in / Sign up

Export Citation Format

Share Document