scholarly journals Multistep flow synthesis of vinyl azides and their use in the copper-catalyzed Huisgen-type cycloaddition under inductive-heating conditions

2011 ◽  
Vol 7 ◽  
pp. 1441-1448 ◽  
Author(s):  
Lukas Kupracz ◽  
Jan Hartwig ◽  
Jens Wegner ◽  
Sascha Ceylan ◽  
Andreas Kirschning
Keyword(s):  
Electromagnetic Induction ◽  
Flow Reactor ◽  
Packed Bed ◽  
Inductive Heating ◽  
Flow Synthesis ◽  
The Third ◽  
Catalytically Active ◽  
Polymer Supported ◽  
Vinyl Azides ◽  
Bed Material

The multistep flow synthesis of vinyl azides and their application in the synthesis of vinyltriazoles is reported. The synthesis relies on a stable polymer-bound equivalent of iodine azide that serves to carry out 1,2-functionalization of alkenes in a telescope flow protocol. The intermediate 2-iodo azides are subjected to a DBU-mediated polymer-supported elimination step yielding vinyl azides in good yield. The third step involves the formation of vinyl triazoles by a copper-catalyzed Huisgen-"click" cycloaddition. The required heat is generated by electromagnetic induction based on copper. Copper serves both as heatable as well as catalytically active packed-bed material inside the flow reactor.

Robust, non-fouling liters-per-day flow synthesis of ultra-small catalytically active metal nanoparticles in a single-channel reactor

2017 ◽  
Vol 2 (5) ◽  
pp. 636-641 ◽  
Author(s):  
Wai Kuan Wong ◽  
Swee Kun Yap ◽  
Yi Chen Lim ◽  
Saif A. Khan ◽  
Frédéric Pelletier ◽  
...  
Keyword(s):  
Metal Nanoparticles ◽  
Palladium Nanoparticles ◽  
Flow Reactor ◽  
Single Channel ◽  
Channel Reactor ◽  
Flow Synthesis ◽  
Continuous Synthesis ◽  
Active Metal ◽  
Catalytically Active ◽  
Non Fouling

Robust, non-fouling, litres-per-day continuous synthesis of catalytically active palladium nanoparticles using triphasic segmented flow in a hybrid milli-meso flow reactor.

Optimized Immobilization Strategy for Dirhodium(II) Carboxylate Catalysts for C−H Functionalization and Their Implementation in a Packed Bed Flow Reactor

2020 ◽  
Vol 132 (44) ◽  
pp. 19693-19699
Author(s):  
Taylor A. Hatridge ◽  
Wenbin Liu ◽  
Chun‐Jae Yoo ◽  
Huw M. L. Davies ◽  
Christopher W. Jones
Keyword(s):  
Flow Reactor ◽  
Packed Bed

scholarly journals Continuous-flow synthesis and application of polymer-supported BODIPY Photosensitisers for the generation of singlet oxygen; process optimised by in-line NMR spectroscopy

2020 ◽  
Vol 10 (1) ◽  
pp. 327-345 ◽  
Author(s):  
Christopher G. Thomson ◽  
Callum M. S. Jones ◽  
Georgina Rosair ◽  
David Ellis ◽  
Jose Marques-Hueso ◽  
...  
Keyword(s):  
Nmr Spectroscopy ◽  
Singlet Oxygen ◽  
Continuous Flow ◽  
Flow Synthesis ◽  
Polymer Supported ◽  
Oxygen Process

Continuous flow synthesis concatenated with continuous flow liquid–liquid extraction for work-up and purification: selective mono- and di-iodination of the imidazole backbone

2016 ◽  
Vol 1 (4) ◽  
pp. 436-444 ◽  
Author(s):  
Audun Drageset ◽  
Hans-René Bjørsvik
Keyword(s):  
Continuous Flow ◽  
Flow Reactor ◽  
Liquid Extraction ◽  
Flow Synthesis ◽  
Liquid Liquid Extraction ◽  
Flow Processes ◽  
Work Up

Flow processes for mono- and di-iodination of the imidazole backbone were devised, developed, and implemented on the multi-jet oscillating disk (MJOD) flow reactor platform.

Comparison of Raschig Ring Packing Pattern via Mean Resident Time using CFD Particle Tracing Technique: Dry Methane Reforming for Case Study

2018 ◽  
Author(s):  
Nattaporn Chutichairattanaphum ◽  
Phavanee Narataruksa ◽  
Karn Pana-Suppamassadu ◽  
Sabaithip Tungkamani ◽  
Chaiwat Prapainainar ◽  
...  
Keyword(s):  
Flow Reactor ◽  
Flow Behavior ◽  
Plug Flow ◽  
Tubular Reactor ◽  
Packed Bed ◽  
Methane Reforming ◽  
Particle Tracing ◽  
Raschig Ring ◽  
Resident Time

This paper aims to study the effect of raschig ring packing patterns using Computational Fluid Dynamics (CFD). CFD module of particle tracing was established to measure particles diffusing through the packed bed. The support raschigs catalyst was modeled in three patterns within a tubular reactor – namely, vertical staggered, chessboard staggered and reciprocal staggered pattern. A case study of Dry Methane Reforming (DMR) was investigated at 600°C, 1 atm. The study of Mean Resident Time (MRT) and E(t) function were investigated to identify the packing pattern performance. The results showed that the minimum value of the E(t), which means the flow behavior, was close to ideal plug flow behavior. MRT can be used to systematically identify the deviation from the ideal plug flow reactor of the three different packing patterns.

Effective thermal conductivity in a packed-bed radial-flow reactor

AIChE Journal ◽  
1987 ◽  
Vol 33 (10) ◽  
pp. 1747-1750 ◽  
Author(s):  
A. L. López de Ramos ◽  
F. F. Pironti
Keyword(s):  
Thermal Conductivity ◽  
Effective Thermal Conductivity ◽  
Radial Flow ◽  
Flow Reactor ◽  
Packed Bed ◽  
Radial Flow Reactor

scholarly journals Modeling and Simulation of the Hydrogenation ofα-Methylstyrene on Catalytically Active Metal Foams as Tubular Reactor Packing

2016 ◽  
Vol 2016 ◽  
pp. 1-10 ◽  
Author(s):  
Farzad Lali ◽  
Felix-Aron Pahner ◽  
Rüdiger Lange
Keyword(s):  
Bubbly Flow ◽  
Experimental Studies ◽  
Tubular Reactor ◽  
Packed Bed ◽  
Hydrogenation Reaction ◽  
Experimental Results ◽  
Packed Bed Reactor ◽  
Orthogonal Collocation ◽  
Reactor Model ◽  
Catalytically Active

This work presents a one-dimensional reactor model for a tubular reactor packed with a catalytically active foam packing with a pore density of 30 PPI in cocurrent upward flow in the example of hydrogenation reaction ofα-methylstyrene to cumene. This model includes material, enthalpy, and momentum balances as well as continuity equations. The model was solved within the parameter space applied for experimental studies under assumption of a bubbly flow. The method of orthogonal collocation on finite elements was applied. For isothermal and polytropic processes and steady state conditions, axial profiles for concentration, temperature, fluid velocities, pressure, and liquid holdup were computed and the conversions for various gas and liquid flow rates were validated with experimental results. The obtained results were also compared in terms of space time yield and catalytic activity with experimental results and stirred tank and also with random packed bed reactor. The comparison shows that the application of solid foams as reactor packing is advantageous compared to the monolithic honeycombs and random packed beds.

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