scholarly journals Synthesis of pyrazolopyrimidinones using a “one-pot” approach under microwave irradiation

2018 ◽  
Vol 14 ◽  
pp. 1222-1228 ◽  
Author(s):  
Mark Kelada ◽  
John M D Walsh ◽  
Robert W Devine ◽  
Patrick McArdle ◽  
John C Stephens
Keyword(s):  
Microwave Irradiation ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
Alkyl Groups

A simple one-pot method for the microwave-assisted synthesis of substituted pyrazolo[1,5-a]pyrimidinones, a core scaffold in many bioactive and pharmaceutically relevant compounds, has been established. A variety of substituents was tolerated at the 2 and 5 positions, including functionalized aryls, heterocycles, and alkyl groups.

Microwave-assisted synthesis of multiply-twinned Au–Ag nanocrystals on reduced graphene oxide for high catalytic performance towards hydrogen evolution reaction

2016 ◽  
Vol 4 (10) ◽  
pp. 3865-3871 ◽  
Author(s):  
Yuchen Qin ◽  
Xiaoping Dai ◽  
Xin Zhang ◽  
Xingliang Huang ◽  
Hui Sun ◽  
...  
Keyword(s):  
Graphene Oxide ◽  
Microwave Irradiation ◽  
Reduced Graphene Oxide ◽  
Hydrogen Evolution Reaction ◽  
Catalytic Performance ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
Reduced Graphene ◽  
Ag Ncs

Multiply-twinned Au–Ag NCs/rGO are prepared by a one-pot method under microwave irradiation and exhibit excellent HER activity and stability.

Impact of microwave irradiation on cyclo-octeno-1,2,3-selenadiazole: formation of selenium nanoparticles and their polymorphs

RSC Advances ◽  
2015 ◽  
Vol 5 (56) ◽  
pp. 44756-44763 ◽  
Author(s):  
Aditi A. Jadhav ◽  
Pawan K. Khanna
Keyword(s):  
Microwave Irradiation ◽  
Selenium Nanoparticles ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Microwave Assisted

In this work a one-pot microwave assisted synthesis of selenium nanoparticles and their different forms, by decomposition of cyclo-octeno-1,2,3-selenadiazole is described first ever time.

Microwave-assisted synthesis of novel 2,3-disubstituted imidazo[1,2-a]pyridines via one-pot three component reactions

RSC Advances ◽  
2015 ◽  
Vol 5 (25) ◽  
pp. 19724-19733 ◽  
Author(s):  
Shaik Karamthulla ◽  
Md. Nasim Khan ◽  
Lokman H. Choudhury
Keyword(s):  
Microwave Irradiation ◽  
Molecular Iodine ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Microwave Assisted ◽  
Three Component Reaction

An expeditious one-pot, metal-free, three-component reaction of arylglyoxals, cyclic 1,3-dicarbonyls and 2-aminopyridines in the presence of molecular iodine under microwave irradiation is reported.

scholarly journals One-Pot Synthesis of Metallopyrazinoporphyrazines Using 2,3-Diaminomaleonitrile and 1,2-Dicarbonyl Compounds Accelerated by Microwave Irradiation

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
Ali Maleki ◽  
Ali Hossein Rezayan
Keyword(s):  
Microwave Irradiation ◽  
Metal Salts ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Dicarbonyl Compounds ◽  
Microwave Assisted ◽  
One Pot Synthesis

A one-pot microwave-assisted synthesis of metallopyrazinoporphyrazines as porphyrazine derivatives carrying six-membered pyrazine rings annulated at the periphery of the tetrapyrrolic macrocycle is described starting from 2,3-diaminomaleonitrile, 1,2-dicarbonyl compounds, metal salts, and urea.

Microwave Mediated Fast Synthesis of Diaminoglyoxime and 3,4-diaminofurazan: Key Synthons for the Synthesis of High Energy Density Materials

2005 ◽  
Vol 2005 (4) ◽  
pp. 245-247 ◽  
Author(s):  
Radhika S Kusurkar ◽  
Shailesh K. Goswami ◽  
Mahadev B. Talawar ◽  
Girish M. Gore ◽  
Shri N. Asthana
Keyword(s):  
Microwave Irradiation ◽  
Hydroxylamine Hydrochloride ◽  
High Energy ◽  
High Energy Density ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Vicarious Nucleophilic Substitution ◽  
Microwave Assisted ◽  
High Energy Density Materials ◽  
Fast Synthesis

This paper reports the first microwave-assisted synthesis of diaminoglyoxime (DAG) and diaminofurazan (DAF). The synthesis involved the vicarious nucleophilic substitution of H of glyoxime using hydroxylamine hydrochloride under microwave irradiation for 2 to 3 min to obtain DAG, which on further irradiation in alkali solution for 20 min yielded DAF. Conversion of glyoxime into DAF was also achieved in a one pot sequence in good overall yield using microwave irradiation.

Microwave-assisted Synthesis of Benzoxazoles Derivatives

2020 ◽  
Vol 7 (3) ◽  
pp. 183-195
Author(s):  
Musa Özil ◽  
Emre Menteşe
Keyword(s):  
Microwave Irradiation ◽  
Reaction Medium ◽  
Pharmaceutical Chemistry ◽  
Conventional Heating ◽  
High Yield ◽  
Microwave Assisted Synthesis ◽  
Microwave Assisted ◽  
Optical Brighteners ◽  
Chemistry Research ◽  
Extensive Class

Background: Benzoxazole, containing a 1,3-oxazole system fused with a benzene ring, has a profound effect on medicinal chemistry research owing to its important pharmacological activities. On the other hand, the benzoxazole derivative has exhibited important properties in material science. Especially in recent years, microwave-assisted synthesis is a technique that can be used to increase diversity and quick research in modern chemistry. The utilization of microwave irradiation is beneficial for the synthesis of benzoxazole in recent years. In this focused review, we provide a metaanalysis of studies on benzoxazole in different reaction conditions, catalysts, and starting materials by microwave technique so far, which is different from conventional heating. Methods: Synthesis of different kind of benzoxazole derivatives have been carried out by microwave irradiation. The most used method to obtain benzoxazoles is the condensation of 2-aminophenol or its derivatives with aldehydes, carboxylic acids, nitriles, isocyanates, and aliphatic amines. Results: Benzoxazole system and its derivatives have exhibited a broad range of pharmacological properties. Thus, many scientists have remarked on the importance of the synthesis of different benzoxazole derivatives. Conventional heating is a relatively inefficient and slow method to convey energy in orientation to the reaction medium. However, the microwave-assisted heating technique is a more effective interior heating by straight coupling of microwave energy with the molecules. Conclusion: In this review, different studies were presented on the recent details accessible in the microwave- assisted techniques on the synthesis of the benzoxazole ring. It presents all examples of such compounds that have been reported from 1996 to the present. Benzoxazoles showed an extensive class of chemical substances not only in pharmaceutical chemistry but also in dyestuff, polymer industries, agrochemical, and optical brighteners. Thus the development of fast and efficient achievement of benzoxazoles with a diversity of substituents in high yield is getting more noteworthy. As shown in this review, microwave-assisted synthesis of benzoxazoles is a very effective and useful technique.

scholarly journals One-Pot Microwave-Assisted Synthesis of Water-Soluble Pyran-2,4,5-triol Glucose Amine Schiff Base Derivative: XRD/HSA Interactions, Crystal Structure, Spectral, Thermal and a DFT/TD-DFT

Crystals ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 117
Author(s):  
Yousef Hijji ◽  
Rajeesha Rajan ◽  
Hamdi Ben Yahia ◽  
Said Mansour ◽  
Abdelkader Zarrouk ◽  
...  
Keyword(s):  
Schiff Base ◽  
Molecular Orbital ◽  
Density Functional ◽  
Condensation Reaction ◽  
3D Structure ◽  
Water Soluble ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Microwave Assisted ◽  
Td Dft

The(3R,4R,6R)-3-(((E)-2-hydroxybenzylidene)amino)-6-(hydroxymethyl)tetrahydro-2H-pyran-2,4,5-triol water-soluble Glucose amine Schiff base (GASB-1) product was made available by condensation of 2-hydroxybenzaldehyde with (3R,6R)-3-amino-6-(hydroxymethyl)-tetra-hydro-2H-pyran-2,4,5-triol under mono-mode microwave heating. A one-pot 5-minute microwave-assisted reaction was required to complete the condensation reaction with 90% yield and without having byproducts. The 3D structure of GASB-1 was solved from single crystal X-ray diffraction data and computed by DFT/6-311G(d,p). The Hirshfeld surface analysis (HSA), molecular electronic potential (MEP), Mulliken atomic charge (MAC), and natural population analysis (NPA) were performed. The IR and UV-Vis spectra were matched to their density functional theory (DFT) relatives and the thermal behavior was resolved in an open-room condition via thermogravimetry/Derivative thermogravimetry (TG/DTG) and differential scanning calorimetry (DSC). The highest occupied molecular orbital/lowest unoccupied molecular orbital (HOMO/LUMO), density of state (DOS), and time-dependence TD-DFT computations were correlated to the experimental electron transfer in water and acrylonitrile solvents.

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