scholarly journals A simple copper-catalyzed two-step one-pot synthesis of indolo[1,2-a]quinazoline

2014 ◽  
Vol 10 ◽  
pp. 2441-2447 ◽  
Author(s):  
Chunpu Li ◽  
Lei Zhang ◽  
Shuangjie Shu ◽  
Hong Liu
Keyword(s):  
Functional Group ◽  
One Pot ◽  
One Pot Synthesis ◽  
Type C ◽  
Quinazoline Derivatives

A convenient CuI/L-proline-catalyzed, two-step one-pot method has been developed for the preparation of indolo[1,2-a]quinazoline derivatives using a sequential Ullmann-type C–C and C–N coupling. This protocol provides an operationally simple and rapid strategy for preparing indolo[1,2-a]quinazoline derivatives and displays good functional group tolerance. All the starting materials are commercial available or can be easily prepared.

Synthesis of pyrazolo[1,5-c]quinazoline derivatives through the copper-catalyzed domino reaction of o-alkenyl aromatic isocyanides with diazo compounds

2020 ◽  
Vol 56 (55) ◽  
pp. 7665-7668 ◽  
Author(s):  
Lu Liu ◽  
Lei Li ◽  
Shukuan Mao ◽  
Xin Wang ◽  
Ming-Dong Zhou ◽  
...  
Keyword(s):  
Diazo Compounds ◽  
Domino Reaction ◽  
Reaction Conditions ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

Various o-alkenyl aromatic isocyanides were prepared from readily available reactants for their double annulation with diazo compounds for a one-pot synthesis of pyrazolo[1,5-c]quinazolines under mild reaction conditions.

Direct Propargylation of ortho-Quinone Methides with Alkynyl Zinc Reagents: An Application to the One-Pot Synthesis of 2,3-Disubstituted Benzofurans

Synlett ◽  
2020 ◽  
Vol 31 (08) ◽  
pp. 818-822
Author(s):  
Hongjun Ren ◽  
Manman Sun ◽  
Jinyu Song ◽  
Lei Wang ◽  
Wenguang Yin ◽  
...  
Keyword(s):  
Transition Metal ◽  
Functional Group ◽  
Quinone Methides ◽  
One Pot ◽  
Metal Free ◽  
Efficient Strategy ◽  
One Pot Synthesis ◽  
Subsequent Cyclization ◽  
The One

A transition-metal-free propargylation of ortho-quinone methides (o-QMs) with alkynyl zinc reagents was achieved. A conjugate alkynylation of an o-QM and subsequent cyclization sequence in the presence of KOt-Bu for the synthesis of 2,3-disubstituted benzofurans in one pot was developed. This efficient strategy exhibits good functional-group compatibility and gives moderate to good yields. The present reaction might serve as an attractive method for the synthesis of polysubstituted benzofurans.

scholarly journals An Efficient One-Pot Multicomponent Synthesis of Tetracyclic Quinazolino[4,3-b]quinazolines by Sequential C–N Bond Formation and Copper-Mediated Aerobic Oxidative Cyclization

Synlett ◽  
2018 ◽  
Vol 29 (13) ◽  
pp. 1717-1722 ◽  
Author(s):  
Manjula Alla ◽  
Gal Potuganti ◽  
Divakar Indukuri
Keyword(s):  
Bond Formation ◽  
Nitrogen Sources ◽  
Oxidative Cyclization ◽  
Multicomponent Synthesis ◽  
One Pot ◽  
Aerobic Conditions ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

An efficient one-pot synthesis of quinazolino[4,3-b]quinazoline derivatives has been accomplished, starting from 2-(2-bromo­phenyl)quinazolin-4(3H)-one, aldehydes, and various nitrogen sources under aerobic conditions. The multicomponent protocol is mediated by copper(I) salts and involves amination of 2-(2-bromophenyl)quinazolin-4(3H)-one, followed by condensation with the aldehyde and an oxidative cyclization to give the target compounds in moderate to good yields.

ChemInform Abstract: Hydrazononitriles as Precursors for 4-Aminotriazoles and 3-Aminoisoxazoles: One Pot Synthesis of Triazolo[1,5-a]quinazoline Derivatives.

ChemInform ◽  
2016 ◽  
Vol 47 (50) ◽  
Author(s):  
Ismail A. Abdelhamid ◽  
Amr M. Abdelmoniem ◽  
Said A. S. Ghozlan ◽  
Holger Butenschoen
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives

One Pot Synthesis of Quinazoline Derivatives by Use of Palladium Catalyzed Carbonylation

Heterocycles ◽  
1985 ◽  
Vol 23 (11) ◽  
pp. 2803 ◽  
Author(s):  
Yoshio Ban ◽  
Miwako Mori ◽  
Hiromi Kobayashi ◽  
Masaya Kimura
Keyword(s):  
One Pot ◽  
One Pot Synthesis ◽  
Palladium Catalyzed ◽  
Quinazoline Derivatives

Fe(III)/l-Valine-Catalyzed One-Pot Synthesis of N-Sulfinyl- and N-Sulfonylimines via Oxidative Cascade Reaction of Alcohols with Sulfinamides or Sulfonamides

Synlett ◽  
2018 ◽  
Vol 29 (09) ◽  
pp. 1232-1238
Author(s):  
Guofu Zhang ◽  
Yunzhe Xing ◽  
Shengjun Xu ◽  
Chengrong Ding ◽  
Shang Shan
Keyword(s):  
Catalytic System ◽  
Functional Group ◽  
Cascade Reaction ◽  
One Pot ◽  
Mild Conditions ◽  
One Pot Synthesis ◽  
Oxidation Of Alcohols

An efficient Fe(III), l-valine, and 4-OH-TEMPO catalytic system was found for the oxidation of alcohols followed by condensation with sulfinamide or sulfonamide in one pot for the synthesis of N-sulfinyl- and N-sulfonylimines compounds under mild conditions. This transformation accommodates a variety of substrates, shows high functional-group tolerance, and affords the corresponding products in good to excellent yields.

ChemInform Abstract: One-Pot Synthesis of Imidazo[1,2-c]quinazoline Derivatives from Nitro-Compounds Reduced by Zinc.

ChemInform ◽  
2010 ◽  
Vol 41 (6) ◽  
Author(s):  
Da-Qing Shi ◽  
Shao-Feng Rong ◽  
Guo-Lan Dou ◽  
Man-Man Wang
Keyword(s):  
Nitro Compounds ◽  
One Pot ◽  
One Pot Synthesis ◽  
Quinazoline Derivatives
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