scholarly journals The influence of light deprivation on implantation in the rat

1971 ◽  
Vol 23 (5) ◽  
pp. 354-355
Author(s):  
Sara C. Gilman ◽  
Gloria J. Fischer
Keyword(s):  
Light Deprivation

PHYSIOLOGICAL EFFECTS OF THE PINEAL GLAND IN ANDROGEN-STERILIZED FEMALE RATS

1970 ◽  
Vol 63 (4) ◽  
pp. 667-678 ◽  
Author(s):  
Russel J. Reiter
Keyword(s):  
Pineal Gland ◽  
Reproductive Organs ◽  
Female Rats ◽  
Inhibitory Influence ◽  
Light Deprivation ◽  
Vaginal Smears ◽  
Adult Rats ◽  
Androgen Treatment ◽  
Postnatal Treatment ◽  
Cervical Ganglia

ABSTRACT The influence of early androgen treatment, light deprivation (by blinding), pinealectomy and superior cervical ganglionectomy on the reproductive system of female rats was tested. Early postnatal treatment of rats with testosterone propionate caused adult rats to exhibit the characteristic signs of androgen sterilization; these included polyfollicular ovaries, normal-sized uteri and persistent vaginal cornification. If early androgentreated rats also were blinded the ovaries were smaller in size and contained fewer follicles, the uteri were greatly reduced in size and the incidence of vaginal oestrus was decreased by approximately 50% If in addition to blinding, androgen-sterilized animals were subjected to either removal of the pineal gland or superior cervical ganglia, the reproductive organs and the vaginal smears were indistinguishable from those of testosterone-treated rats with eyes. These data indicate that the inhibitory influence of blinding on the pituitary-ovarian axis was mediated through the sympathetic nervous system and the pineal gland. The restraining influence of light deprivation on the growth of the reproductive organs was not permanent as illustrated by the fact that if these animals were kept to 120 days of age the ovaries and uteri grew to the same level as those of pinealectomized control rats.

Effect of Long-Term Light Deprivation on α-Tocopherol Content in Rats during Ontogeny

2021 ◽  
Vol 170 (3) ◽  
pp. 294-298
Author(s):  
I. V. Baishnikova ◽  
T. N. Ilyina ◽  
E. A. Khizhkin ◽  
V. A. Ilyukha ◽  
I. A. Vinogradova
Keyword(s):  
Tocopherol Content ◽  
Light Deprivation

scholarly journals Antidepressant Effect of Blue Light on Depressive Phenotype in Light-Deprived Male Rats

2020 ◽  
Vol 79 (12) ◽  
pp. 1344-1353
Author(s):  
Qinghe Meng ◽  
Jianjun Jiang ◽  
Xiaohong Hou ◽  
Lixia Jia ◽  
Xiaoxiao Duan ◽  
...  
Keyword(s):  
Blue Light ◽  
Seasonal Affective Disorder ◽  
Neural Mechanism ◽  
Light Therapy ◽  
Male Rats ◽  
Antidepressant Effect ◽  
Light Deprivation ◽  
Sprague Dawley ◽  
Neurotrophic Activity ◽  
Immobility Time

Abstract Blue light has been previously reported to play a salient role in the treatment of seasonal affective disorder. The present study aimed to investigate whether blue light had antidepressant effect on light-deprivation-induced depression model, and the underlying visual neural mechanism. Blue light mitigated depression-like behaviors induced by light deprivation as measured by elevated sucrose preference and reduced immobility time. Blue light enhanced melanopsin expression and light responses in the retina. We also found the upregulation of serotonin and brain derived neurotrophic factor expression in the c-fos-positive areas of rats treated with blue light compared with those maintained in darkness. The species gap between nocturnal albino (Sprague-Dawley rat) and diurnal pigmented animals (human) might have influenced extrapolating data to humans. Blue light has antidepressant effect on light-deprived Sprague-Dawley rats, which might be related to activating the serotonergic system and neurotrophic activity via the retinoraphe and retinoamygdala pathways. Blue light is the effective component of light therapy for treatment of depression.

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