scholarly journals The influence of exogenous testosterone and corticosterone on the social behavior of prepubertal male rats

1983 ◽  
Vol 21 (3) ◽  
pp. 232-234 ◽  
Author(s):  
Michael J. Meaney ◽  
Jane Stewart
Keyword(s):  
Social Behavior ◽  
Male Rats ◽  
The Social

Effects of single and repeated restraint on the social behavior of male rats

1993 ◽  
Vol 53 (5) ◽  
pp. 937-942 ◽  
Author(s):  
Maria Emanuela Albonetti ◽  
Francesca Farabollini
Keyword(s):  
Social Behavior ◽  
Male Rats ◽  
The Social

The social behavior of male rats administered an adult-onset calorie restriction regimen

2009 ◽  
Vol 96 (4-5) ◽  
pp. 581-585 ◽  
Author(s):  
Antonina Govic ◽  
Elizabeth A. Levay ◽  
Stephen Kent ◽  
Antonio G. Paolini
Keyword(s):  
Social Behavior ◽  
Calorie Restriction ◽  
Male Rats ◽  
Adult Onset ◽  
The Social

scholarly journals The Role of Oxytocin, Vasopressin, and D-Cycloserine in Remediating Social Behavior in Rats with Amygdala Lesions

2012 ◽  
Vol 1 (1) ◽  
pp. 53-59
Author(s):  
Kristina Lauren Scanlan ◽  
Alan Gittis ◽  
Robin McGovern
Keyword(s):  
Social Behavior ◽  
Neurodevelopmental Disorder ◽  
Autism Spectrum ◽  
Social Impairment ◽  
Female Rats ◽  
Male Rats ◽  
Sexually Dimorphic ◽  
Social Deficits ◽  
The Social ◽  
Amygdala Lesions

Autism is a common neurodevelopmental disorder that affects communication and social behavior.  To reduce the social deficits characteristic of autism, the compounds oxytocin, arginine vasopressin, D-cycloserine, and D-cycloserine + oxytocin were explored as therapeutic agents.  Twenty-one Long Evans Hooded rats underwent a bilateral amygdala lesion, which reduced the time of social interactions between the pairs of animals.  Upon administration of D-cycloserine, the social deficits induced by the lesions were significantly reversed in both sexes.  In addition, it was observed that the efficacy of the treatments was affected by the sex of the subjects.  Male rats had the largest increase in social behavior when given D-cycloserine.  However, female rats experienced the largest reduction in social impairment when administered oxytocin.  Thus, sexually dimorphic treatments should be further investigated for individuals with autism spectrum disorders.

The ketogenic diet affects the social behavior of young male rats

2017 ◽  
Vol 179 ◽  
pp. 168-177 ◽  
Author(s):  
Daniela Kasprowska-Liśkiewicz ◽  
Arkadiusz D. Liśkiewicz ◽  
Marta M. Nowacka-Chmielewska ◽  
Joanna Nowicka ◽  
Andrzej Małecki ◽  
...  
Keyword(s):  
Social Behavior ◽  
Ketogenic Diet ◽  
Young Male ◽  
Male Rats ◽  
The Social

A stranger in the family? On the social behavior of a leucistic collared peccary (Pecari tajacu) with pigmented conspecifics

2019 ◽  
Vol 60 (2) ◽  
pp. 303-305
Author(s):  
Valdir Leite da Silva ◽  
José Cândido ◽  
José Nelson Campanha ◽  
Doraci R. de Oliveira ◽  
Carla Gheler-Costa ◽  
...  
Keyword(s):  
Social Behavior ◽  
The Social ◽  
The Family ◽  
Pecari Tajacu ◽  
Collared Peccary

scholarly journals Pharmacological modulation of AMPA receptors rescues specific impairments in social behavior associated with the A350V Iqsec2 mutation

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Renad Jabarin ◽  
Nina Levy ◽  
Yasmin Abergel ◽  
Joshua H. Berman ◽  
Amir Zag ◽  
...  
Keyword(s):  
Social Behavior ◽  
Ampa Receptors ◽  
Emotional State ◽  
Social Discrimination ◽  
Glutamatergic Synapses ◽  
Behavioral Deficits ◽  
Pharmacological Modulation ◽  
The Social ◽  
State Preference ◽  
Molecular Pathophysiology

AbstractIn this study we tested the hypothesis that pharmacological modulation of glutamatergic neurotransmission could rescue behavioral deficits exhibited by mice carrying a specific mutation in the Iqsec2 gene. The IQSEC2 protein plays a key role in glutamatergic synapses and mutations in the IQSEC2 gene are a frequent cause of neurodevelopmental disorders. We have recently reported on the molecular pathophysiology of one such mutation A350V and demonstrated that this mutation downregulates AMPA type glutamatergic receptors (AMPAR) in A350V mice. Here we sought to identify behavioral deficits in A350V mice and hypothesized that we could rescue these deficits by PF-4778574, a positive AMPAR modulator. Using a battery of social behavioral tasks, we found that A350V Iqsec2 mice exhibit specific deficits in sex preference and emotional state preference behaviors as well as in vocalizations when encountering a female mouse. The social discrimination deficits, but not the impaired vocalization, were rescued with a single dose of PF-4778574. We conclude that social behavior deficits associated with the A350V Iqsec2 mutation may be rescued by enhancing AMPAR mediated synaptic transmission.

Field Dependence and Self-Disclosure

1973 ◽  
Vol 36 (3) ◽  
pp. 735-738 ◽  
Author(s):  
Joaquin F. Sousa-Poza ◽  
Robert Rohrberg ◽  
Ernest Shulman
Keyword(s):  
Social Behavior ◽  
Field Dependence ◽  
The Self ◽  
Social Stimuli ◽  
Self Disclosure ◽  
Field Independent ◽  
The Social ◽  
Field Dependent ◽  
Personality Theories

Some characteristics of the social behavior of field-dependents as well as their superior recognition of ambiguous social stimuli led to the hypothesis that they would show greater self-disclosure than field-independents. This hypothesis was tested by administering the 60-item Jourard Self-disclosure Questionnaire (JSDQ) to 13 field-dependent and 13 field-independent Ss. In terms of total self-disclosure scores, field-dependents showed significantly (.025) higher levels than field-independents. Results are discussed in light of personality theories which emphasize the role of self-conceptual transactions in the development of the self.

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