scholarly journals Associative symmetry as measured in the B-Ar paradigm: A stage analysis

1974 ◽  
Vol 4 (2) ◽  
pp. 139-140
Author(s):  
Richard C. Ney ◽  
Robert L. Solso
Keyword(s):  
Associative Symmetry ◽  
Stage Analysis

PERILAKU RANGKAK SUSUT TERHADAP LENDUTAN STRUKTUR JEMBATAN BENTANG PANJANG

2017 ◽  
Vol 13 (4) ◽  
pp. 260 ◽  
Author(s):  
Baskoro Abdi Praja ◽  
Andreas Triwiyono
Keyword(s):  
Time Dependent ◽  
Construction Stage ◽  
Stage Analysis

Jembatan Lemah Ireng 1 pada ruas jalan Tol Semarang-Bawen terbuat dari beton prategang dengan panjang total 879 m. Pada masa konstruksi dua perbedaan kondisi teknik terhadap rencana, yakni perubahan material pasir dan perubahan perpindahan traveler. Keduanya diduga sebagai penyebab perbedaan elevasi desain dengan elevasi aktual sehingga dilakukan levelling aspal dengan tebal bervariasi. Jembatan ini didesain untuk memenuhi masa layan 100 tahun namun berdasarkan kondisi aktual, diperlukan peninjauan terhadap perilaku dan kuat layan jembatan hingga umur rencana. Dengan pengaruh variasi pembebanan jangka panjang (rangkak susut) dan kondisi perubahan teknis akibat penambahan aspal, penelitian rangkak susut ini perlu dilakukan untuk mengetahui perilaku lendutan pada gelagar boks jembatan hingga umur rencana. Beberapa tahapan pembebanan yang dilakukan adalah menerapkan beban levelling aspal, dan beban rangkak dan susut dengan menggunakan variasi durasi jangka panjang dengan interval 5, 10 , 15, 20, 40, 60, 80 dan 100 tahun. Analisis dilakukan secara linear statik serta memanfaatkan fasilitas Construction Stage Analysis untuk efek time-dependent pada software Midas Civil 2011. Penelitian ini dilakukan dengan hanya meninjau aksi tetap. Perilaku rangkak susut jembatan cukup signifikan di 5 tahun pertama setelah konstruksi selesai. Lendutan maksimum rangkak susut dan total berada di bentang terpanjang (P4-P5)  masing-masing sebesar 17,53 dan 25,71 cm. Lendutan yang terjadi hingga umur rencana 100 tahun masih dalam batas izin, namun tetap perlu pengawasan yang terencana. Dampak minimum rangkak susut terhadap total lendutan pada jembatan Lemah Ireng 1 sebesar 45%. Hal ini menunjukkan rangkak susut terhadap defleksi total hingga umur rencana merupakan efek jangka panjang yang relatif besar.

Pharmacokinetics of Propofol after a Single Dose in Children Aged 1–3 Years with Minor Burns

1996 ◽  
Vol 84 (3) ◽  
pp. 526-532 ◽  
Author(s):  
I. Murat ◽  
V. Billard ◽  
J. Vernois ◽  
M. Zaouter ◽  
P. Marsol ◽  
...  
Keyword(s):  
Single Dose ◽  
Surface Area ◽  
Total Body Surface Area ◽  
Central Compartment ◽  
Pharmacokinetic Parameters ◽  
Systemic Clearance ◽  
Older Children ◽  
Noncompartmental Analysis ◽  
Two Stage ◽  
Stage Analysis

Background No complete pharmacokinetic profile of propofol is yet available in children younger than 3 yr, whereas clinical studies have demonstrated that both induction and maintenance doses of propofol are increased with respect to body weight in this age group compared to older children and adults. This study was therefore undertaken to determine the pharmacokinetics of propofol after administration of a single dose in aged children 1-3 yr requiring anesthesia for dressing change. Methods This study was performed in 12 children admitted to the burn unit and in whom burn surface area was less than or equal to 12% of total body surface area. Exclusion criteria were: unstable hemodynamic condition, inappropriate fluid loading, associated pulmonary injury, or burn injury older than 2 days. Propofol (4 mg.kg(-1))plus fentanyl (2.5 microg.kg(-1)) was administered while the children were bathed and the burn area cleaned during which the children breathed spontaneously a mixture of oxygen and nitrous oxide (50:50). Venous blood samples of 300 microl were obtained at 5, 15, 30, 60, 90, and 120 min, and 3, 4, 8, and 12 thereafter injection; an earlier sample was obtained from 8 of 12 children. The blood concentration curves obtained for individual children were analyzed by three different methods: noncompartmental analysis, mixed effects population model, and standard two-stage analysis. Results Using noncompartmental analysis, total clearance of propofol (+/-SD) was 0.053+/-0.013l.kg(-1).min(-1), volume of distribution at steady state9.5 +/- 3.7l.kg(-1),and residence time 188 +/- 85 min. Propofol pharmacokinetics were best described by a weight-proportional three-compartmental model in both population and two-stage analysis. Estimated and derived pharmacokinetic parameters were similar using these two pharmacokinetic approaches. Results of population versus two-stage analysis are as follow: systemic clearance 0.049 versus 0.048 l.kg(-).min(-1), volume of central compartment 1.03 versus 0.95 l.kg(-1), volume of steady state 8.09 versus 8.17 l.kg(-1). Conclusions The volume of the central compartment and the systemic clearance were both greater than all values reported in older children and adults. This is consistent with the increased propofol requirements for both induction and maintenance of anesthesia in children 1-3 yr. (Key words: Anesthesia: pediatric. Pharmacokinetics: propofol.)

Identifying the most informative cut-off of psa to define biochemical recurrence after radical prostatectomy: A stage-by-stage analysis

2021 ◽  
Vol 79 ◽  
pp. S1649
Author(s):  
L. Nocera ◽  
G. Gandaglia ◽  
N. Fossati ◽  
A. Stabile ◽  
V. Cucchiara ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Biochemical Recurrence ◽  
Stage Analysis

Analysis of the Effect of Multi-Row and Multi-Passage Aerodynamic Interaction on the Forced Response Variation in a Compressor Configuration: Part 2 — Effects of Additional Structural Mistuning

2017 ◽  
Author(s):  
Johann Gross ◽  
Malte Krack ◽  
Harald Schoenenborn
Keyword(s):  
Epistemic Uncertainty ◽  
Element Model ◽  
Forced Response ◽  
Aerodynamic Loading ◽  
Multi Stage ◽  
Blade Row ◽  
Random Mistuning ◽  
Response Variation ◽  
Stage Analysis ◽  
Turbomachinery Design

The prediction of aerodynamic blade forcing is a very important topic in turbomachinery design. Usually, the wake from the upstream blade row and the potential field from the downstream blade row are considered as the main causes for excitation, which in conjunction with relative rotation of neighboring blade rows, give rise to dynamic forcing of the blades. In addition to those two mechanisms so-called Tyler-Sofrin (or scattered or spinning) modes, which refer to the acoustic interaction with blade rows further up- or downstream, may have a significant impact on blade forcing. In particular, they lead to considerable blade-to-blade variations of the aerodynamic loading. In part 1 of the paper a study of these effects is performed on the basis of a quasi 3D multi-row and multi-passage compressor configuration. Part 2 of the paper proposes a method to analyze the interaction of the aerodynamic forcing asymmetries with the already well-studied effects of random mistuning stemming from blade-to-blade variations of structural properties. Based on a finite element model of a sector, the equations governing the dynamic behavior of the entire bladed disk can be efficiently derived using substructuring techniques. The disk substructure is assumed as cyclically symmetric, while the blades exhibit structural mistuning and linear aeroelastic coupling. In order to avoid the costly multi-stage analysis, the variation of the aerodynamic loading is treated as an epistemic uncertainty, leading to a stochastic description of the annular force pattern. The effects of structural mistuning and stochastic aerodynamic forcing are first studied separately and then in a combined manner for a blisk of a research compressor without and with aeroelastic coupling.

scholarly journals Associative symmetry and memory theory

2002 ◽  
Vol 30 (6) ◽  
pp. 823-840 ◽  
Author(s):  
Michael J. Kahana
Keyword(s):  
Memory Theory ◽  
Associative Symmetry

Cytolytic assessment of hyperacute rejection and production of nuclear transfer embryos using hCD46-transgenic porcine embryonic germ cells

Zygote ◽  
2009 ◽  
Vol 17 (2) ◽  
pp. 101-108 ◽  
Author(s):  
Ji Young Won ◽  
Kwang Sung Ahn ◽  
Alice M. Sorrell ◽  
Susa Shin ◽  
Soon Young Heo ◽  
...  
Keyword(s):  
Nuclear Transfer ◽  
Regulatory Protein ◽  
Blastocyst Stage ◽  
Hyperacute Rejection ◽  
Complement Regulatory Protein ◽  
Transgenic Pigs ◽  
Embryonic Germ Cells ◽  
Transgenic Embryos ◽  
Stage Analysis ◽  
Human Xenotransplantation

SummaryHuman complement regulatory protein hCD46 may reduce the hyperacute rejection (HAR) in pig-to-human xenotransplantation. In this study, an hCD46 gene was introduced into porcine embryonic germ (EG) cells. Treatment of human serum did not affect the survival of hCD46-transgenic EG cells, whereas the treatment significantly reduced the survival of non-transgenic EG cells (p < 0.01). The transgenic EG cells presumably capable of alleviating HAR were transferred into enucleated oocytes. Among 235 reconstituted oocytes, 35 (14.9%) developed to the blastocyst stage. Analysis of individual embryos indicated that 80.0% (28/35) of embryos contained the transgene hCD46. The result of the present study demonstrates resistance of hCD46-transgenic EG cells against HAR, and the usefulness of the transgenic approach may be predicted by this cytolytic assessment prior to actual production of transgenic pigs. Subsequently performed EG cell nuclear transfer gave rise to hCD46-transgenic embryos. Further study on the transfer of these embryos to recipients may produce hCD46-transgenic pigs.

Steady Stage Analysis

2018 ◽  
pp. 229-355
Author(s):  
Abdel Razik Ahmed Zidan ◽  
Mohammed Ahmed Abdel Hady
Keyword(s):  
Steady Stage ◽  
Stage Analysis
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