scholarly journals Detection by the guinea pig of acoustic stimulation and of electrical stimulation of the brain

1966 ◽  
Vol 1 (3) ◽  
pp. 137-141 ◽  
Author(s):  
George M. Gerken
Keyword(s):  
Electrical Stimulation ◽  
Guinea Pig ◽  
Acoustic Stimulation ◽  
The Brain ◽  
Stimulation Of

PREFERENTIAL RELEASE OF OXYTOCIN FROM THE NEUROHYPOPHYSIS AFTER ELECTRICAL STIMULATION OF THE AFFERENT PATH OF THE MILK-EJECTION REFLEX IN THE BRAIN OF THE GUINEA-PIG

1968 ◽  
Vol 40 (2) ◽  
pp. 205-214 ◽  
Author(s):  
J. S. TINDAL ◽  
G. S. KNAGGS ◽  
A. TURVEY
Keyword(s):  
Blood Pressure ◽  
Electrical Stimulation ◽  
Guinea Pig ◽  
Arterial Blood Pressure ◽  
Pituitary Stalk ◽  
Milk Ejection ◽  
Arterial Blood ◽  
Milk Ejection Reflex ◽  
The Brain ◽  
Stimulation Of

SUMMARY Discrete portions of the afferent path of the milk-ejection reflex have been explored in the brain of the lactating guinea-pig. Both intramammary pressure and arterial blood pressure were recorded to detect release of oxytocin and vasopressin. It was found that the milk-ejection responses which occurred after electrical stimulation of the pathway in the midbrain and hypothalamus were caused by the release of oxytocin without detectable release of vasopressin. A mixture of oxytocin and vasopressin, in the ratio of approximately 3:1, was released only after electrical stimulation of the rostral tuberal region of the hypothalamus adjacent to the pituitary stalk. It is concluded that the afferent path in the brain of the guinea-pig studied is concerned with the preferential release of oxytocin from the neurohypophysis and that it is the pathway of the milk-ejection reflex.

scholarly journals Adenine derivatives as neurohumoral agents in the brain. The quantities liberated on excitation of superfused cerebral tissues

1972 ◽  
Vol 130 (4) ◽  
pp. 975-981 ◽  
Author(s):  
Ian Pull ◽  
Henry McIlwain
Keyword(s):  
Electrical Stimulation ◽  
Guinea Pig ◽  
Adenine Nucleotides ◽  
Specific Radioactivity ◽  
Acid Extraction ◽  
Free Medium ◽  
Hydrolysis Of ◽  
The Brain ◽  
Stimulation Of ◽  
Adenine Derivatives

Adenine nucleotides of guinea-pig neocortical tissues were labelled by incubation with [14C]adenine and excess of adenine was then removed by superfusion with precursor-free medium. Adenine derivatives released from the tissue during continued superfusion, including a period of electrical stimulation of the tissue, were collected by adsorption and examined after elution and concentration. The stimulation greatly increased the 14C output, and material collected during and just after stimulation had a u.v. spectrum which indicated adenosine to be a major component. The additional presence of inosine and hypoxanthine was shown by chromatography and adenosine was identified also by using adenosine deaminase. Total adenine derivatives released from the tissue during a 10min period of stimulation were obtained as hypoxanthine, after deamination and hydrolysis of adenosine and inosine, and amounted to 159nmol/g of tissue. This corresponded to the release of approx. 7pmol/g of tissue per applied stimulus. The hypoxanthine sample derived from superfusate hypoxanthine, inosine and adenosine was of similar specific radioactivity to the sample of inosine separated chromatographically, and each was of higher specific radioactivity than the adenine nucleotides obtained by cold-acid extraction of the tissue.

Effects of Electrical Stimulation of the Superior Cervical Ganglion on Cochlear Blood Flow in Guinea Pig

1993 ◽  
Vol 113 (2) ◽  
pp. 146-151 ◽  
Author(s):  
Tian-Ying Ren ◽  
E. Laurikainen ◽  
W. S. Quirk ◽  
J. M. Miller ◽  
A. L. Nuttall
Keyword(s):  
Blood Flow ◽  
Electrical Stimulation ◽  
Guinea Pig ◽  
Superior Cervical Ganglion ◽  
Cochlear Blood Flow ◽  
Cervical Ganglion ◽  
Stimulation Of
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