scholarly journals Recent advances in the surgical treatment of pancreatic cancer

2001 ◽  
Vol 7 (5) ◽  
pp. 622
Author(s):  
A Shankar ◽  
RCG Russell
Keyword(s):  
Pancreatic Cancer ◽  
Surgical Treatment ◽  
Recent Advances

scholarly journals Recent Advances in Nanoparticle-Mediated Diagnosis and the Treatment of Pancreatic Cancer

2021 ◽  
Vol 22 (15) ◽  
pp. 8060
Author(s):  
Andreea Nedelcu ◽  
Teodora Mocan ◽  
Cristiana Grapa ◽  
Lucian Mocan
Keyword(s):  
Pancreatic Cancer ◽  
Surgical Treatment ◽  
Survival Rate ◽  
Solid Tumors ◽  
Present Review ◽  
Novel Therapies ◽  
Curative Intent ◽  
Recent Advances ◽  
Exciting Opportunity

Pancreatic cancer (PC), one of the most lethal solid tumors in humans, has a five-year survival rate of only 4%. Surgical treatment is the only accepted therapy with curative intent because the vast majority of these tumors are chemoresistant. Unfortunately, due to the aggressive nature of these tumors, fewer than 20% are resectable when the first symptoms occur. Novel therapies are required to overcome all these therapeutic issues, and the development of active nanocarriers represents an exciting opportunity to improve PC outcomes. The present review focuses on recent advances in the field of nanotechnology with application in PC treatment.

RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH CHRONIC PANCREATITIS AND THE RISK OF CANCER AFTER SURGICAL TREATMENT

2018 ◽  
Vol 64 (2) ◽  
pp. 228-233
Author(s):  
Vladimir Lubyanskiy ◽  
Vasiliy Seroshtanov ◽  
Ye. Semenova
Keyword(s):  
Pancreatic Cancer ◽  
Chronic Pancreatitis ◽  
Surgical Treatment ◽  
Fibrous Tissue ◽  
Pancreatic Head ◽  
Head Region ◽  
Intestinal Anastomoses ◽  
Resection Of The Pancreas ◽  
Risk Of Cancer

The aim: To analyze results of surgical treatment of patients with chronic pancreatitis (CP) and to assess the causes of pancreatic cancer after surgical treatment. Materials and methods: 137 patients had duodenum-preserving resections of the pancreas. Results: In the histological examination of the pancreas it was established that the growth of fibrous tissue was registered in patients with CP., which in 19 (13.8%) almost completely replaced the acinar tissue. In the long term after the operation from 6 months to 2 years in 8 patients (5.8%) pancreatic cancer was detected. Possible causes of tumor origin were analyzed, the value of preservation of ductal hypertension, which affects the state of the duct’s epithelium, was established. The most commonly used for treatment of chronic pancreatitis the Frey surgery removed pancreatic hypertension but in two patients during the operation an insufficient volume of the pancreatic head was reconstructed. In the case of the abandonment of a large array of fibrous tissue, local hypertension was retained in the region of the ductal structures of the head, which led to the transformation of the duct epithelium. An essential factor in the problem of the preservation of pancreatic hypertension were the stenosis of pancreatic intestinal anastomoses, they arose in the long term in 4 operated patients. With stenosis of anastomosis after duodenum-preserving resection both the hypertension factor and the regeneration factor could be realized, which under certain circumstances might be significant. Conclusion: After resection of the pancreas for CP cancer was diagnosed in 5.8% of patients. The main method of preventing the risk of cancer was performing the Frey surgery for CP eliminating pancreatic hypertension in the head region of the pancreas. Diagnosis of stenosis in the late period after resection of the pancreas was an important element in the prevention of recurrence of cancer since a timely reconstructive operation could improve the drainage of duct structures.

scholarly journals MO31-1 Surgical treatment for pulmonary oligometastases in the patients with pancreatic cancer who underwent pancreatectomy

2021 ◽  
Vol 32 ◽  
pp. S318
Author(s):  
Maeda Shingo ◽  
Ryoji Takada ◽  
Kenji Ikezawa ◽  
Kazuma Daiku ◽  
Yutaro Abe ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Surgical Treatment

Surgical treatment of pancreatic cancer: The role of adjuvant and multimodal therapies

2007 ◽  
Vol 33 (7) ◽  
pp. 817-823 ◽  
Author(s):  
J. Kleeff ◽  
C.W. Michalski ◽  
H. Friess ◽  
M.W. Büchler
Keyword(s):  
Pancreatic Cancer ◽  
Surgical Treatment

Variations in Surgical Treatment and Outcomes of Patients With Pancreatic Cancer: A Population-Based Study

2007 ◽  
Vol 15 (1) ◽  
pp. 175-185 ◽  
Author(s):  
Anand Govindarajan ◽  
Jensen C. C. Tan ◽  
Nancy N. Baxter ◽  
Natalie G. Coburn ◽  
Calvin H. L. Law
Keyword(s):  
Pancreatic Cancer ◽  
Surgical Treatment ◽  
Population Based ◽  
Population Based Study
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