scholarly journals What characterizes cancer family history collection tools? A critical literature review

2018 ◽  
Vol 25 (4) ◽  
Author(s):  
J.E. Cleophat ◽  
H. Nabi ◽  
S. Pelletier ◽  
K. Bouchard ◽  
M. Dorval
Keyword(s):  
Risk Assessment ◽  
Family History ◽  
Cancer Risk ◽  
Electronic Health Records ◽  
Health Professionals ◽  
Cancer Risk Assessment ◽  
Health Records ◽  
Cancer Family ◽  
Cancer Family History ◽  
Electronic Health

Background Many tools have been developed for the standardized collection of cancer family history (fh). However, it remains unclear which tools have the potential to help health professionals overcome traditional barriers to collecting such histories. In this review, we describe the characteristics, validation process, and performance of existing tools and appraise the extent to which those tools can support health professionals in identifying and managing at-risk individuals.Methods Studies were identified through searches of the medline, embase, and Cochrane central databases from October 2015 to September 2016. Articles were included if they described a cancer fh collection tool, its use, and its validation process.Results Based on seventy-nine articles published between February 1978 and September 2016, 62 tools were identified. Most of the tools were paper-based and designed to be self-administered by lay individuals. One quarter of the tools could automatically produce pedigrees, provide cancer-risk assessment, and deliver evidence-based recommendations. One third of the tools were validated against a standard reference for collected fh quality and cancer-risk assessment. Only 3 tools were integrated into an electronic health records system.Conclusions In the present review, we found no tool with characteristics that might make it an efficient clinical support for health care providers in cancer-risk identification and management. Adequately validated tools that are connected to electronic health records are needed to encourage the systematic identification of individuals at increased risk of cancer.

scholarly journals Primary care physicians' use of family history for cancer risk assessment

2010 ◽  
Vol 11 (1) ◽  
Author(s):  
Brian S Flynn ◽  
Marie E Wood ◽  
Takamaru Ashikaga ◽  
Alan Stockdale ◽  
Greg S Dana ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Primary Care ◽  
Family History ◽  
Cancer Risk ◽  
Primary Care Physicians ◽  
Cancer Risk Assessment

scholarly journals Circulating growth factor concentrations and breast cancer risk: a nested case-control study of IGF-1, IGFBP-3, and breast cancer in a family-based cohort

2020 ◽  
Vol 22 (1) ◽  
Author(s):  
Kelsey R. Monson ◽  
Mandy Goldberg ◽  
Hui-Chen Wu ◽  
Regina M. Santella ◽  
Wendy K. Chung ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Family History ◽  
Breast Cancer Risk ◽  
Cancer Risk ◽  
Average Risk ◽  
Breast Cancer Family ◽  
Cancer Family ◽  
Cancer Family History ◽  
Breast Cancer Family History ◽  
Igfbp 3

Abstract Background Insulin-like growth factor 1 (IGF-1) and binding protein 3 (IGFBP-3) are associated with breast cancer in women at average risk of cancer. Less is known whether these biomarkers also predict risk in women with breast cancer family history. Methods We conducted a nested case-control study within the New York site of the Breast Cancer Family Registry (BCFR, n = 80 cases, 156 controls), a cohort enriched for breast cancer family history. Using conditional logistic regression, we estimated the association between IGF-1 and IGFBP-3 levels and breast cancer risk and examined whether this risk differed by predicted absolute breast cancer risk based on pedigree models. Results The overall association between IGF-1 or IGFBP-3 elevation (≥ median in controls) and breast cancer risk was elevated, but not statistically significant (IGF-1 OR = 1.37, 95% CI = 0.66–2.85; IGFBP-3 OR = 1.62, 95% CI = 0.81–3.24). Women with elevated predicted absolute 10-year risk ≥ 3.4% and elevated IGFBP-3 (≥ median) had more than a 3-fold increased risk compared to women with lower predicted absolute 10-year risk (< 3.4%) and low IGFBP-3 (OR = 3.47 95% CI = 1.04–11.6). Conclusions These data offer some support that the overall magnitude of the associations between IGF-1 and IGFBP3 seen in average risk cohorts may be similar in women enriched with a strong breast cancer family history.

Cancer risk assessment using an automated electronic patient-facing tool for the collection and evaluation of family history.

2016 ◽  
Vol 34 (15_suppl) ◽  
pp. e13055-e13055
Author(s):  
Leigh A Baumgart ◽  
Kristen J Vogel Postula ◽  
Shaun A Walters ◽  
Jonathan C Silverstein ◽  
William A Knaus
Keyword(s):  
Risk Assessment ◽  
Family History ◽  
Cancer Risk ◽  
Cancer Risk Assessment

Hereditary Cancer Family History Risk Assessment Outcomes in an Obstetrics and Gynecology Population

2014 ◽  
Vol 123 ◽  
pp. 93S
Author(s):  
Frederica Lofquist ◽  
Christine Lee ◽  
Kelsey Moyes ◽  
Stephanie A. Hamilton ◽  
Jonathan Nelson ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Family History ◽  
Hereditary Cancer ◽  
Obstetrics And Gynecology ◽  
Cancer Family ◽  
Cancer Family History ◽  
Assessment Outcomes
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