scholarly journals Quality of life in pediatric cancer survivors: contributions of parental distress and psychosocial family risk

2018 ◽  
Vol 25 (1) ◽  
pp. 41 ◽  
Author(s):  
N.M. Racine ◽  
M. Khu ◽  
K. Reynolds ◽  
G.M.T. Guilcher ◽  
F.S.M. Schulte

Background Pediatric survivors of childhood cancer are at increased risk of poor quality of life and social-emotional outcomes following treatment. The relationship between parent psychological distress and child adjustment in pediatric cancer survivors has been well established. However, limited research has examined the factors that may buffer this association. The current study examined the associations between psychosocial family risk factors, parental psychological distress, and health-related quality of life (hrql) in pediatric cancer survivors.Methods Fifty-two pediatric cancer survivors (34 males, 18 females, mean age = 11.92) and their parents were recruited from a long-term cancer survivor clinic. Children and their parents who consented to participate completed the Pediatric Quality of Life Inventory 4.0. Parents completed a demographic information form, the Psychosocial Assessment Tool (pat 2.0) and the Brief Symptom Inventory (bsi). The Intensity of Treatment Rating (itr-3) was evaluated by the research team.Results Multiple regression analyses revealed that parental psychological distress negatively predicted parent reported hrql, while treatment intensity, gender, and psychosocial risk negatively predicted parent and child-reported hrql. Psychosocial risk moderated the association between parent psychological distress and parent-reported child hrql (p = 0.03), whereby parents with high psychological distress but low levels of psychosocial risk reported their children to have higher hrql.Conclusion Low levels of family psychosocial risk buffer the impact of parent psychological distress on child hrql in pediatric cancer survivors. The findings highlight the importance of identifying parents and families with at-risk psychological distress and psychosocial risk in order to provide targeted support interventions to mitigate the impact on hrql.

2012 ◽  
Vol 34 (3) ◽  
pp. 194-199 ◽  
Author(s):  
Begül Yağc-Küpeli ◽  
Canan Akyüz ◽  
Serhan Küpeli ◽  
Münevver Büyükpamukçu

2020 ◽  
Vol 35 (6) ◽  
pp. 953-953
Author(s):  
Lozano G ◽  
Camper M ◽  
Holland A

Abstract Objective Sleep-related problems have been shown to adversely affect pediatric cancer survivors’ mood, behavior, and quality of life (Litsenburg et al., 2011). Depressed mood also contributes to decreased quality of life in pediatric leukemia survivors (Jankowska-Polańska et al., 2019). However, minimal research has considered how sleep and mood affect cognitive outcomes in pediatric cancer survivors. The present study utilized both direct assessment and parent report to investigate how sleep and mood affect attentional functioning in this population. Method Parents of 54 pediatric cancer survivors (59% Caucasian, 44% female, mean age at testing = 11.27 years) referred for clinical evaluation completed the Behavior Assessment System for Children-3 (BASC-3) and Patient-Reported Outcomes Measurement Information System (PROMIS). A subset of survivors also completed the Conners Continuous Performance Test-3 (CPT-3). Variables selected for analysis were BASC-3 Depression, Hyperactivity, Attention Problems; PROMIS Sleep Impairment, Fatigue; CPT-3 Omissions. Results Multiple linear regressions found that patients whose parents rated them higher on Depression and Sleep Impairment demonstrated more Omission errors (ΔR2 = .265, ΔF[4,42] = 3.785, p = .01). Similarly, multiple linear regressions found that parents who rated their children higher on Depression, Fatigue, and Sleep Impairment were more likely to rate their children high on Hyperactivity (ΔR2 = .182, ΔF[4,49] = 2.725, p < .05). Higher Depression ratings also predicted ratings of worse Attention Problems (r[53] = .330, p = .007). Conclusions Findings suggest that both depressive symptoms and sleep impairment may adversely affect attention functioning following pediatric cancer treatment. This highlights the importance of addressing mood and sleep in interventions to address attention difficulties in pediatric oncology survivors. Future directions for research are discussed.


2007 ◽  
Vol 49 (3) ◽  
pp. 298-305 ◽  
Author(s):  
Kathleen A. Meeske ◽  
Sunita K. Patel ◽  
Stephanie N. Palmer ◽  
Mary B. Nelson ◽  
Aimee M. Parow

2021 ◽  
Author(s):  
Valentin Benzing ◽  
Valerie Siegwart ◽  
Janine Spitzhüttl ◽  
Jürg Schmid ◽  
Michael Grotzer ◽  
...  

2004 ◽  
Vol 22 (2) ◽  
pp. 354-360 ◽  
Author(s):  
Philippe Rauch ◽  
Joelle Miny ◽  
Thierry Conroy ◽  
Lionel Neyton ◽  
Francis Guillemin

Purpose To identify factors affecting the quality of life (QoL) of disease-free survivors of rectal cancer. Patients and Methods One hundred twenty-one patients in complete remission more than 2 years after diagnosis were asked to complete three QoL questionnaires: the European Organization for Research and Treatment of Cancer (EORTC) QLQ-C30; its colorectal module, QLQ-CR38; and the Duke generic instrument. Results Patients reported less pain (P = .002) than did controls drawn from the general population. EORTC QLQ-C30 physical scores were also higher among rectal cancer survivors than in the general Norwegian or German population (P = .0005 and P = .002, respectively). Unexpectedly, stoma patients reported better social functioning than did nonstoma patients (P = .005), with less anxiety (P = .008) and higher self-esteem (P = .0002). In the present authors' experience, the QLQ-CR38 does not discriminate between these groups. Residual abdominal or pelvic pain and constipation had the most negative influence on QoL. Conclusion QoL is high among rectal cancer survivors, including stoma patients. Simultaneous use of several QoL questionnaires appears to have value in follow-up and in monitoring the effects of therapy. The impact of residual pain and constipation on long-term QoL should be considered when establishing a treatment regimen.


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