Influential factors of translation unit in traditional Chinese medicine

2009 ◽  
Vol 7 (2) ◽  
pp. 187-190
Author(s):  
MJ Qian
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Influential Factors

scholarly journals Symptoms Based on Deficiency Syndrome in Traditional Chinese Medicine Might Be Predictor of Frailty in Elderly Community Dwellers

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Zhen Qi ◽  
Bei-Ling Wu ◽  
Chuan Chen ◽  
Zhi-Hua Yu ◽  
Ding-Zhu Shen ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Risk Prediction ◽  
Dietary Habits ◽  
Influential Factors ◽  
Lower Limbs ◽  
Chronic Obstructive ◽  
Frailty Phenotype ◽  
New Model ◽  
Community Dwellers

Background. The most widely used frailty phenotype and frailty indexes are either time-consuming or complicated, thus restricting their generalization in clinical practice; and therefore, an easier and faster screening tool is needed to be developed. Objective. To select sensitive symptoms in traditional Chinese medicine (TCM) and study whether they can improve the risk prediction of frailty. Methods. This is a cross-sectional study enrolling 2249 Chinese elderly community dwellers. Data were collected via face-to-face inquiries, anthropometric measurements, laboratory tests, and community health files. Frailty was the main outcome measure, and it was evaluated by Fried’s frailty phenotype (FP). The ordinal logistic regression model was used to identify the factors associated with frailty. The risk assessment plot was used to compare the discriminative ability for frailty among models with and without TCM symptoms. Results. The identified sensitive influential factors for frailty included age, education level, dietary habits, chronic obstructive pulmonary disease, diabetes, cerebral infarction, osteoporosis, cold limbs, lethargy and laziness in speaking and moving, weakness of lower limbs, slow movement, dry mouth and throat, and glazed expression. The risk prediction for “frailty cumulative components ≥1” was not significantly increased, while for “frailty cumulative components ≥2”, a new model developed with the above selected TCM symptoms had a higher AUC than the baseline model without it (0.79 VS 0.81, P = 0.002 ). And the NRI and IDI for the new model were 41.4% ( P = 0.016 ) and 0.024% ( P = 0.041 ), respectively. Conclusion. This research might provide an easier and faster way for early identification and risk prediction of frailty in elderly community dwellers.

The Protective Effects of Gardenia jasminoides (Fructus Gardenia) on Amyloid-β-Induced Mouse Cognitive Impairment and Neurotoxicity

2018 ◽  
Vol 46 (02) ◽  
pp. 389-405 ◽  
Author(s):  
Cai-Xia Zang ◽  
Xiu-Qi Bao ◽  
Lin Li ◽  
Han-Yu Yang ◽  
Lu Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Amyloid Β ◽  
Influential Factors ◽  
Chinese Herbs ◽  
Protective Effects ◽  
Disease Modifying Drugs ◽  
Gardenia Jasminoides ◽  
Cholinergic Dysfunction ◽  
Single Target

Alzheimer’s disease (AD) is the most common neurodegenerative disease in the world. Although the exact causes of AD have not yet been fully elucidated, cholinergic dysfunction, mitochondrial damage, oxidative stress and neuroinflammation have been recognized as influential factors. Current drugs that are designed to address only a single target are unable to mitigate or prevent the progression of this complicated disease, so new disease-modifying drugs are urgently needed. Chinese herbs with thousand years of effective usage might be a good source for potential drugs. Gardenia jasminoides J. Ellis (Fructus Gardenia) is a common traditional Chinese medicine with tranquilizing effects, which is an important component of widely-used traditional Chinese medicine for dementia. GJ-4 is crocin richments extracted from Gardenia jasminoides J. Ellis. In our study, we attempted to observe the effects of GJ-4 on learning and memory injury induced by amyloid-[Formula: see text] 25-35 (A[Formula: see text] injection in mice. Treatment with GJ-4 dose-dependently enhanced the memory and cognition ability of A[Formula: see text]-injected mice. Preliminary mechanistic studies revealed the protective effect of GJ-4 was related to its protection of neurons and cholinergic dysfunction. The mechanistic results also indicated that GJ-4 could enhance antioxidant capacity and attenuate neuroinflammation. Our results implied that GJ-4 might be a promising drug to improve cognitive and memory impairment, with multiple targets.

scholarly journals The Correlation between Demographical and Lifestyle Factors and Traditional Chinese Medicine Constitution among Macau Elderly Individuals

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Qian Bai ◽  
Yaochen Chuang ◽  
Yonghua Zhao ◽  
Yao Wang ◽  
Pu Ge ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
The Elderly ◽  
Education Level ◽  
Influential Factors ◽  
Lifestyle Behaviors ◽  
Elderly Individuals ◽  
Yin Deficiency ◽  
Qi Stagnation ◽  
Sleeping Habits

Objectives. To measure the distributed characteristics of Traditional Chinese Medicine (TCM) constitutions, as well as related factors with biased TCM constitutions among the elderly individuals in Macau. Methods. The elderly individuals from elderly healthcare centers located in Macao Peninsula, Taipa, and Coloane were selected as research samples. The basic information questionnaire and the Constitution in Chinese Medicine Questionnaire (CCMQ) for elderly were employed. Descriptive analysis was applied to illustrate demographical characteristics and TCM constitution distribution. Exploratory factor analysis (EFA) was conducted to explore potential factors influencing biased constitutions, and weight of each variable for constitution was further calculated. Results. A total of 313 participants were recruited. Eighty-six (27.48%) elderly were identified as balanced constitution; others were biased constitutions accounting for 72.52%. Distribution differences related to gender and age were identified among participants with unbalanced constitutions. Four biased constitutions were further analyzed with EFA. For qi-stagnation and yang-deficiency constitutions, three similar factors were determined in the domains of education, sleeping habits, and lifestyle behaviors, successively. Although four factors were identified in phlegm-dampness constitution, the latter two belonged to lifestyle behaviors and the former two were education and sleeping habits. For yin-deficiency constitution, education, tobacco-alcohol consumption, sleeping habits, and exercise were four dimensions of potential influential factors. Tobacco consumption, sleep, and exercise duration weighted the most for qi-stagnation constitution; sleep duration, education level, and sugar-containing beverage intake for phlegm-dampness; length of education, alcohol consumption, and education level for yang-deficiency constitution; and weekly exercise hours, sleep duration, and education level for yin-deficiency constitution. Conclusion. The prevalence rate of biased constitutions was relatively high among elderly residents in Macau. Relations between demographical and lifestyle behavioral factors and biased constitutions were identified in this study. Controlling these influential factors might be beneficial for health management of Macau elderly individuals.

Sign in / Sign up

Export Citation Format

Share Document