Establishment of Caco-2 cell monolayer model and standard operation procedure for assessing intestinal absorption of chemical components of traditional Chinese medicine

2007 ◽  
Vol 5 (6) ◽  
pp. 634-641 ◽  
Author(s):  
Xiuwei Yang
2014 ◽  
Vol 42 (05) ◽  
pp. 1071-1098 ◽  
Author(s):  
Mao-Xing Li ◽  
Xi-Rui He ◽  
Rui Tao ◽  
Xinyuan Cao

In the present review, the literature data on the chemical constituents and biological investigations of the genus Pedicularis are summarized. Some species of Pedicularis have been widely applied in traditional Chinese medicine. A wide range of chemical components including iridoid glycosides, phenylpropanoid glycosides (PhGs), lignans glycosides, flavonoids, alkaloids and other compounds have been isolated and identified from the genus Pedicularis. In vitro and in vivo studies indicated some monomer compounds and extracts from the genus Pedicularis have been found to possess antitumor, hepatoprotective, anti-oxidative, antihaemolysis, antibacterial activity, fatigue relief of skeletal muscle, nootropic effect and other activities.


Humaniora ◽  
2016 ◽  
Vol 7 (1) ◽  
pp. 122
Author(s):  
Mariana Mariana ◽  
Heribertus Sunu Budihardjo

Research goal of this study was to know the program production process of Liputan Cilik DAAI TV in Jakarta. Method used in this study was a qualitative method with analysis participatory observation and in-depth interviews with the crew involved in this program. Result of this study finds that there are three stages of the program production process, they are pre production, production and post-production programs, and processes of SWOT analysis (Strength, Weakness, Opportuniy, Threats). This program has done production in accordance with the SOP (standard operation procedure) although it is aired on television non-commercial. This program does not only provide the entertainment, but also contains the elements education. 


2018 ◽  
Vol 4 (1) ◽  
Author(s):  
Dong Li ◽  
Yang An ◽  
Jianfang Zhao ◽  
Jing Wang ◽  
Xue Yuan

2017 ◽  
Vol 3 (6) ◽  
pp. 62
Author(s):  
Shahid Raza ◽  
Jalil Ahmad

LCL is operating an aerobic composting plant at Lahore that has been purchased from and installed by the Menart Composting Company, Belgium. Since municipal solid waste (MSW) in Lahore is heterogeneous a screening drum (MTR 1850) installed to screen the waste before composting with additional possibility for hand-sorting of recyclables in a sorting belt. This Standard Operation Procedure (SOP) has been prepared for and adopted by the composting plant of the Lahore Compost Ltd (LCL). The SOP intends to ensure that LCL adopts the identified best practices in the plant, operates it through standard recommended procedures; and takes necessary corrective actions when required


2020 ◽  
Vol 21 (12) ◽  
pp. 969-978
Author(s):  
Yang Wang ◽  
Lu Zhang ◽  
Shuang Gu ◽  
Zhaorui Yin ◽  
Zhe Shi ◽  
...  

Background: With significant clinical effects, traditional Chinese medicine (TCM) has been attracting increasing interest of the world’s scientific community. However, TCM contains immense amounts of chemical components. It is a great challenge to objectively evaluate the correlation between the in vivo process and the therapeutic effect of TCM. The purpose of this systematic review was to summarize the recent investigation (from 2017 to 2019) on preclinical pharmacokinetics (PK) of TCM via liquid chromatography coupled with mass spectrometry (LC-MS/MS). Method: We reviewed the published articles regarding the PK of TCM by LC-MS/MS. In addition, we summarized information on PK parameter of bioactive components, single herb and traditional Chinese medicine prescriptions. Results: The vast majority of literature on preclinical PK of TCM uses single oral administration, the biological matrix is mostly rat plasma, and the main PK parameters include AUC, Cmax, Tmax and T1/2, etc. Conclusion: Although LC-MS/MS can be used for high-throughput analysis, the characterization of in vivo processes of TCM still has a long way. With the advantages of high sensitivity, high specificity and simple operation, the increasingly mature LC-MS/MS technology will play an important role in the PK study of TCM.


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