A study on detecting specific antibodies of hemorrhagic fever with renal syndrome and treatment with integrated traditional Chinese and Western medicine

2004 ◽  
Vol 2 (1) ◽  
pp. 20-23 ◽  
Author(s):  
Feng Chu
2016 ◽  
Vol 134 ◽  
pp. 161-166 ◽  
Author(s):  
Isolde Schuster ◽  
Marc Mertens ◽  
Bernd Köllner ◽  
Tomáš Korytář ◽  
Markus Keller ◽  
...  

Author(s):  
N. G. Varfolomeeva ◽  
A. V. Ermakov ◽  
N. F. Vasilenko ◽  
G. P. Shkarlet ◽  
O. V. Maletskaya ◽  
...  

Landscape-geographical and climatic peculiarities of the Stavropol Region, high abundance of mosquito and ticks, the diversity of wild mammal and bird species, developed agriculture and infrastructure create favorable conditions for circulation of arboviruses and hantaviruses, emergence of cases of viral infections, which sometimes cause serious epidemic complications. CHF natural focus actively functions in the territory of the Stavropol Region at present. Detected is presence of West Nile fever, tick-born encephalitis, Batai fever agents and specific antibodies, as well as hemorrhagic fever with renal syndrome agent.


2012 ◽  
Vol 93 (2) ◽  
pp. 221-225
Author(s):  
V G Shakirova ◽  
I M Khaertynova ◽  
K S Khaertynov

Aim. To determine the diagnostic significance of antibodies to Hantavirus in patients with hemorrhagic fever with renal syndrome, depending on the period and the severity of the course of disease. Methods. Studied was the content of specific antibodies (immunoglobulins G) to hantaviruses in blood serum in the rapidly precipitating and slowly precipitating circulating immune complexes by enzyme immunoassay using a test system «Hantagnost» in modification. Studied were 226 patients with hemorrhagic fever with renal syndrome (24 patients with mild form, 105 with moderate and 97 patients with severe form of the disease) in the febrile, oliguric and polyuric periods. Results. Specific antibodies (immunoglobulins G) were present already in the febrile period of the disease in all (100%) patients in the serum and in the rapidly precipitating circulating immune complexes. Antibodies in the slowly precipitating complexes in the febrile period were found only in patients with severe and moderate forms of hemorrhagic fever with renal syndrome, in subsequent periods they were found significantly more frequently in patients with a severe course of disease. Severe forms of hemorrhagic fever with renal syndrome caused the most pronounced serologic response with a maximal content of immunoglobulins G to Hantaviruses in the oliguric period. During the period of polyuria the severe forms of hemorrhagic fever with renal syndrome were accompanied by significantly lower levels of free circulating antibodies and a high level of bound antibodies compared with moderate and mild forms of the disease. Conclusion. In patients with hemorrhagic fever with renal syndrome anti-Hantavirus antibodies (immunoglobulins G) in serum and in the rapidly precipitating immune complexes are detected already at the early stages of the disease in 100% of the cases; the frequency of detection of antibodies in the slowly precipitating circulating immune complexes in the early stages depends on the severity of disease: they are present in 100% of patients with a severe form of the disease, in 50% - with the moderate form, and with the mild form - can not be detected.


2000 ◽  
Vol 5 (1) ◽  
pp. 5-11 ◽  
Author(s):  
S. Ya. Gaidamovich ◽  
A. M. Butenko ◽  
H. V. Leschinskaya

A total of 78 cases of laboratory acquired infections occurred at D. I. Ivanovsky Institute of Virology, M. P. Chumakov Institute of Poliomyelitis and Viral Encephalitis and Rostov na Donu Institute of Epidemiology, Microbiology and Hygiene. All these cases were caused by accidental infection of the staff with the following viruses: Venezuelan equine encephalomyelitis (n=34), Kyasanur forest disease (n=1), Omsk hemorrhagic fever (n=1), Crimean-Congo hemorrhagic fever (CCHF) (n=2), Dhori (n=5), vesicular stomatitis (n=1), Machupo (n=3), and hemorrhagic fever with the renal syndrome (n=31). The majority of cases were caused by inhaling virus aerosols. All cases were a result of accidents or neglect of safety measures. Diagnoses were confirmed by virus isolation and/or detection of specific antibodies in convalescent serum. With the exception of one lethal case of CCHF, patients recovered without disability. The pathogenicity of Dhori virus in man was discovered as a result of laboratory infection of 5 staff members.


Author(s):  
James A. Lake

The understanding of ribosome structure has advanced considerably in the last several years. Biochemists have characterized the constituent proteins and rRNA's of ribosomes. Complete sequences have been determined for some ribosomal proteins and specific antibodies have been prepared against all E. coli small subunit proteins. In addition, a number of naturally occuring systems of three dimensional ribosome crystals which are suitable for structural studies have been observed in eukaryotes. Although the crystals are, in general, too small for X-ray diffraction, their size is ideal for electron microscopy.


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