scholarly journals EXPERIENCE OF COMBINED USE OF TRIBEX AND CARLIV IN EXCTRETORY-TOXIC INFERTILITY IN MEN

2017 ◽  
pp. 44-50
Author(s):  
Юрий Заседа ◽  
Руслан Соломенный ◽  
Фарид Шыхалиев
Keyword(s):  
Prospective Study ◽  
Sperm Count ◽  
Outpatient Department ◽  
Health Clinic ◽  
Study Analysis ◽  
Research Results ◽  
Effi Ciency ◽  
Combined Use ◽  
Group A ◽  
Initial Cycle

Purpose of the study – analysis of the eff ectiveness of combined use of «Tribex» and «Carliv» drugs at man`s infertility in the initial cycle of spermatogenesis.Materials and methods. A clinical prospective study was conducted, in which 30 patients from the outpatient department of the «Men’s Health» clinic took part, who had a decrease in fertility (a pathology was detected in two consecutive studies of ejaculate, associated with excretory-toxic infertility).Research results. The study found the high effi ciency of the combined use of «Treblex» and «Charles», in conjunction with the optional use of non-steroidal anti-infl ammatory drugs, anti-bacterial compounds and physiotherapeutic procedures on a number of spermogram indicators: volume, color, acidity, viscosity, number of sperm in 1 ml, total sperm count, sperm aggregation, mobility (group A + B), presence of leukocytes in sight, mucus.Conclusions The expressed positive clinical eff ect of the use of «Tribex» and «Carliv» drugs on the bioreological characteristics of the seminal fl uid and the indicators of spermatogenesis (number and mobility of sperm) in excretory-toxic infertility in men was found.

Simple descriptors and simple rules of the International Ovarian Tumor Analysis (IOTA) Group: a prospective study of combined use for the description of adnexal masses

2015 ◽  
Vol 195 ◽  
pp. 7-11 ◽  
Author(s):  
Almudena Peces Rama ◽  
María Carmen Llanos Llanos ◽  
María Luisa Sánchez Ferrer ◽  
Juan Luis Alcázar Zambrano ◽  
Antonio Martínez Mendoza ◽  
...  
Keyword(s):  
Prospective Study ◽  
Ovarian Tumor ◽  
Adnexal Masses ◽  
Combined Use ◽  
Simple Rules ◽  
Group A ◽  
A Prospective Study

scholarly journals Prospective study of hair recovery after (neo)adjuvant chemotherapy with scalp cooling in Japanese breast cancer patients

2021 ◽  
Author(s):  
Shozo Ohsumi ◽  
Sachiko Kiyoto ◽  
Mina Takahashi ◽  
Seiki Takashima ◽  
Kenjiro Aogi ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Prospective Study ◽  
Cancer Patients ◽  
Scalp Cooling ◽  
Breast Cancer Patients ◽  
Chemotherapy Infusion ◽  
Group A ◽  
Neo Adjuvant Chemotherapy ◽  
Group B

Abstract Purpose Scalp cooling during chemotherapy infusion to mitigate alopecia for breast cancer patients is becoming widespread; however, studies regarding hair recovery after chemotherapy with scalp cooling are limited. We conducted a prospective study of hair recovery after chemotherapy with scalp cooling. Patients and methods One hundred and seventeen Japanese female breast cancer patients who completed planned (neo)adjuvant chemotherapy using the Paxman Scalp Cooling System for alopecia prevention were evaluated for alopecia prevention in our prospective study. We evaluated their hair recovery 1, 4, 7, 10, and 13 months after chemotherapy. Primary outcomes were grades of alopecia judged by two investigators (objective grades) and patients’ answers to the questionnaire regarding the use of a wig or hat (subjective grades). Results Of 117 patients, 75 completed scalp cooling during the planned chemotherapy cycles (Group A), but 42 discontinued it mostly after the first cycle (Group B). Objective and subjective grades were significantly better in Group A than in Group B throughout 1 year, and at 4 and 7 months after chemotherapy. When we restricted patients to those with objective Grade 3 (hair loss of > 50%) at 1 month, Group A exhibited slightly faster hair recovery based on the objective grades than Group B. There was less persistent alopecia in Group A than in Group B. Conclusions Scalp cooling during chemotherapy infusion for Japanese breast cancer patients increased the rate of hair recovery and had preventive effects against persistent alopecia.

MOUNTING EVIDENCE IN SUPPORT OF A HYPOTHESIS

2021 ◽  
pp. 217-218
Author(s):  
Skandhan KP ◽  
Chaitrali G ◽  
Prasad B.S
Keyword(s):  
Genital Tract ◽  
Sperm Count ◽  
Study Analysis ◽  
Male Genital Tract ◽  
Male Genital

Aim: A study analysis supporting reports on a hypothesis. Background: The function of epididymis is considered as responsible for making a meaningful motionless state for spermatozoa assuring sperms do not escape from male genital tract by its motility. A hypothesis stated repeated ejaculation shall lead to increase sperm count and motility. Review results: Studies showed frequent ejaculations done by men and similar studies conducted in animals support this hypothesis. Conclusion: This method should be benecial to at least patients whose sperm count and motility is less. Clinical signicance: when hypothesis is proved, clinician may advice this patients with oligozoospermia, oligoasthenozoospermia to follow repeated ejaculation instead of storing semen for several days as advised currently

scholarly journals A Prospective Study of Vitamin D Supplement in Thyroidectomy Patients Based on Relative Decline of Parathyroid Hormone

2021 ◽  
Vol 12 ◽  
Author(s):  
Qing Hao ◽  
Yun Qin ◽  
Wanjun Zhao ◽  
Lingyun Zhang ◽  
Han Luo
Keyword(s):  
Vitamin D ◽  
Parathyroid Hormone ◽  
High Risk ◽  
Prospective Study ◽  
Oral Calcium ◽  
Group A ◽  
Relative Decline ◽  
A Prospective Study ◽  
Vitamin D Supplement ◽  
Intravenous Calcium

Background: In postthyroidectomy patients, hypocalcemia is the most common complication to prolong hospital stay and decrease patients’ satisfaction. Based on current evidence, it is recommended to supply vitamin D to patients with high risk of developing hypocalcemia. However, how to stratify the risk of patients remains challenging.Aim: We conducted a prospective study to evaluate the effect of vitamin D supplement (calcitriol) on high-risk hypocalcemia patients based on relative decline of parathyroid hormone (RDP).Method: RDP was calculated by the difference between preoperative and postoperative first-day PTH divided by preoperative PTH and presented as percentage. Patients who underwent total thyroidectomy in addition to bilateral central compartment dissection were enrolled prospectively and were divided into two cohorts: Cohort I: patients with RDP ≤70% and Cohort II: patients with RDP >70%. Patients in Cohort I were then randomly assigned to Group A or B, and patients in Cohort II were randomly assigned to Group C or D. All groups received oral calcium, and patients in Groups B and D also received calcitriol. All patients were followed for one year. In the study, standard procedure dictates that only oral calcium is given to patients whose RDP ≤70% and that oral calcium and calcitriol are given to patients whose RDP >70%. Therefore, Cohort I Group A and Cohort II Group D are controls in this study.Results: The incidence of clinical hypocalcemia in Groups A and D (the controls) was 11.0% (10/91), and 17.6% (16/91) required additional intravenous calcium. Of note, no patients developed permanent hypocalcemia. Furthermore, calcitriol supplement did not have significant impact on clinical outcomes between Group A and B in Cohort I. By contrast, calcitriol supplement distinctly improved clinical outcome by comparing Groups C and D (Cohort II), as marked by clinical hypocalcemia, need of requiring intravenous calcium, and long-termed decreased levels of PTH.Conclusion: Supplying calcitriol based on RDP cutoff of 70% may be a wise practice in thyroidectomy patients, and RDP 70% may be a useful predictor to stratify high-risk patients.

scholarly journals Topical Isotretinoin in Acne Vulgaris

2018 ◽  
Vol 29 (2) ◽  
pp. 1-5
Author(s):  
M Moksedur Rahman ◽  
M Abdullah ◽  
M Moazzem Hossain ◽  
MA Siddique ◽  
M Nessa ◽  
...  
Keyword(s):  
Side Effects ◽  
Adverse Effects ◽  
Prospective Study ◽  
Acne Vulgaris ◽  
Topical Therapy ◽  
Outpatient Department ◽  
College Hospital ◽  
Once Daily ◽  
Medical College ◽  
Cutaneous Reactions

This study was carried out to evaluate the efficacy, safety and adverse effects of topical isotretinoin 0.05% gel in the treatment of acne vulgaris. This prospective study was undertaken in Skin & VD outpatient department of Rajshahi Medical College Hospital, Rajshahi. One hundred patients with mild tomoderate acne vulgaris were enrolled and were instructed to apply isotretinoin 0.05% gel once daily at night for 12 weeks. Patients were followed up at 2,4,8 and 12 weeks for efficacy and tolerability. Efficacy was measured by counting facial inflammatory and noninflammatory lesions and by grading acne severity. Cutaneous tolerance was assessed by determining erythema, scaling and burning with pruritus.Response was excellent in 80%of cases.None of the cutaneous reactions was severe, all were mild and well tolerated.Nobody had to discontinue the therapy for side effects. This study confirms that isotretinoin 0.05% gel is safe and effective topical therapy for mild to moderate acnevulgaris.TAJ 2016; 29(2): 1-5

scholarly journals 424: Uterocervical angle does not predict spontaneous preterm birth in either a low-risk or high-risk group: A prospective study

2018 ◽  
Vol 218 (1) ◽  
pp. S258
Author(s):  
Courtney Olson-Chen ◽  
Kam Szlachetka ◽  
Dzhamala Gilmandyar ◽  
Erica Faske ◽  
Elizabeth Fountaine ◽  
...  
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Prospective Study ◽  
Risk Group ◽  
High Risk Group ◽  
Low Risk ◽  
Spontaneous Preterm Birth ◽  
Group A ◽  
A Prospective Study

A Comparison between Placement of three interrupted sutures after Triangular Three-snip Punctoplasty vs conventional Triangular Three-snip Punctoplasty for treatment of lower punctal stenosis

2021 ◽  
Author(s):  
Hesham Mohammed Abdulhady ◽  
Hany Khairy ◽  
Amr Awara ◽  
Sameh S. Mandour
Keyword(s):  
Prospective Study ◽  
Surgical Outcome ◽  
Group A ◽  
Group B ◽  
Postoperative Improvement ◽  
Punctal Stenosis

Abstract Aim is to evaluate surgical outcome of Triangular Three-snip Punctoplasty (TSP) with three interrupted sutures and compare it to conventional Triangular Three-snip Punctoplasty (TSP) in treatment of acquired lower punctal stenosis. Methods This prospective study included 40 eyelids of 24 patients with acquired lower punctal stenosis grade 1 or grade 2 were classified in two groups. Group A was treated by triangular 3-snip punctoplasty of the lower punctum followed by three interrupted sutures at the posterior ampulla and group B was treated by conventional triangular 3-snip punctoplasty of the lower punctum. Grade of epiphora and grade of FDDT were measured preoperative then post-operative after 1 week, 1 month, 3 months and 6 months. Success was defined as postoperative improvement of epiphora and FDDT grading with no restenosis to occur. Results from 20 eyelids in group A, 16 cases showed success (80%) with patent puncta, 2 cases (10%) showed no change and 2 cases (10%) showed failure with restenosis. While from 20 eyelids in group B, 14 cases showed success (60%) with patent puncta, 4 cases (20%) showed no change and 4 cases (20%) showed failure with restenosis. Conclusion proposed triangular 3-snip punctoplasty of the lower punctum followed by three interrupted sutures seems to have better results compared to conventional triangular 3-snip punctoplasty of the lower punctum in treatment of grade 1 or 2 lower punctal stenosis.

Clinical and Microbiologic Changes Associated With the Combined Use of a Powered Toothbrush and a Triclosan/Copolymer Dentifrice: A 3-Year Prospective Study

2007 ◽  
Vol 78 (9) ◽  
pp. 1708-1717 ◽  
Author(s):  
Anna Bogren ◽  
Ricardo P. Teles ◽  
Gay Torresyap ◽  
Anne D. Haffajee ◽  
Sigmund S. Socransky ◽  
...  
Keyword(s):  
Prospective Study ◽  
Combined Use ◽  
Powered Toothbrush

Is Bladder Ultrasound Indicated as Part of the Routine Investigation of Haematuria?

Ultrasound ◽  
2011 ◽  
Vol 19 (4) ◽  
pp. 209-213
Author(s):  
V E Purnell ◽  
S Desai ◽  
J Husain ◽  
J Dodgeon
Keyword(s):  
Prospective Study ◽  
Gold Standard ◽  
Intravenous Urography ◽  
Appointment Scheduling ◽  
Kappa Score ◽  
Time Burden ◽  
Ultrasound Findings ◽  
Group A ◽  
Bladder Pathology ◽  
A Prospective Study

Many patients presenting with haematuria undergo intravenous urography, renal tract ultrasound and cystoscopy. Renal tract ultrasound includes imaging of the bladder, which can significantly increase scan times by necessitating bladder filling, which can impact negatively on appointment scheduling. Little published literature exists on whether ultrasound of the bladder in the presence of haematuria is of any clinical benefit. This study aims to redress this by comparing bladder ultrasound to the gold standard of cystoscopy and also by assessing temporal implications in this patient group. A prospective study was undertaken where 96 consecutive urology-referred patients had their bladder ultrasound findings compared with the findings of cystoscopy under the headings of mass, trabeculation, diverticulum, stone and fistula. Ultrasound had poor sensitivity (47.8%), but good specificity (94.5%) in detecting the predefined bladder pathologies with a poor Kappa score of 0.33 when compared with cystoscopy. In addition, there was a significant time burden placed on the list by including bladder scanning as part of the renal tract sonographic assessment. In conclusion, bladder ultrasound is not shown to be a clinically useful adjunct to cystoscopy for the detection of bladder pathology. We would recommend that, in the setting of haematuria, ultrasound be used only for upper tract assessment.

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