Evaluation of Body Mass Index, Hematocrit, Erythrocyte Sedimentation Rate and Total Protein in Voluntary and Commercial Blood Donors in Nigeria: Advocating for Simultaneous Screening for Nutritional Status

Aim. To identify clinical and laboratory peculiarities of a combined clinical course of metabolic and articular syndromes. Materials and Methods. In the research 126 individuals participated. They were arranged into 3 groups: the 1st group included 46 patients with comorbid pathology, the 2nd group – 44 patients with metabolic syndrome, and the 3d group – 36 patients with articular syndrome. The following parameters were evaluated: anthropometric data (height, body mass, body mass index, waist circumference), lipid spectrum, glycohemoglobin, nonspecific markers of inflammation, daily profile of arterial pressure. Results. In the group with comorbid pathology higher average values of body mass were recorded – 115.8 [60;140] kg in comparison with the 2nd and 3d groups – 93.5 [72;130] and 71.5 [58;98] kg, respectively; erythrocyte sedimentation rate – 18.3 [5;34] mm/h was reliably higher than in the 2nd group (11.5 [2;24] mm/h), and median cholesterol (6.18 [5,39;6,85] mmol/L) was higher than in the 3d group (4.82 [3,48;5,61] mmol/L). In the 1st and 2nd groups higher average values of systolic arterial pressure were recorded in comparison with the 3d group – 158,5 [120;190]; 154,6 [115;190] and 126,4 [96;168] mm Hg, respectively. Conclusions. In patients with combined metabolic and articular syndromes higher values of body mass and systolic arterial pressure were identified. Based on the laboratory findings, parameters of cholesterol and erythrocyte sedimentation rate were higher in patients with comorbid condition than in those with the isolated pathologies.

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Clinical and laboratory peculiarities of combined clinical course of metabolic and articular syndromes

I P Pavlov Russian Medical Biological Herald ◽

10.23888/pavlovj20182229-237 ◽

2018 ◽

Vol 26 (2) ◽

pp. 229-237

Author(s):

Dar'ja Yu. Gorbunova ◽

Zinaida A. Morgunova ◽

Oleg M. Uryasyev

Keyword(s):

Arterial Pressure ◽

Erythrocyte Sedimentation Rate ◽

Body Mass ◽

Sedimentation Rate ◽

Clinical Course ◽

Systolic Arterial Pressure ◽

Comorbid Condition ◽

Laboratory Findings ◽

Markers Of Inflammation ◽

Erythrocyte Sedimentation

Aim. To identify clinical and laboratory peculiarities of a combined clinical course of metabolic and articular syndromes. Materials and Methods. In the research 126 individuals participated. They were arranged into 3 groups: the 1st group included 46 patients with comorbid pathology, the 2nd group – 44 patients with metabolic syndrome, and the 3d group – 36 patients with articular syndrome. The following parameters were evaluated: anthropometric data (height, body mass, body mass index, waist circumference), lipid spectrum, glycohemoglobin, nonspecific markers of inflammation, daily profile of arterial pressure. Results. In the group with comorbid pathology higher average values of body mass were recorded – 115.8 [60;140] kg in comparison with the 2nd and 3d groups – 93.5 [72;130] and 71.5 [58;98] kg, respectively; erythrocyte sedimentation rate – 18.3 [5;34] mm/h was reliably higher than in the 2nd group (11.5 [2;24] mm/h), and median cholesterol (6.18 [5,39;6,85] mmol/L) was higher than in the 3d group (4.82 [3,48;5,61] mmol/L). In the 1st and 2nd groups higher average values of systolic arterial pressure were recorded in comparison with the 3d group – 158,5 [120;190]; 154,6 [115;190] and 126,4 [96;168] mm Hg, respectively. Conclusions. In patients with combined metabolic and articular syndromes higher values of body mass and systolic arterial pressure were identified. Based on the laboratory findings, parameters of cholesterol and erythrocyte sedimentation rate were higher in patients with comorbid condition than in those with the isolated pathologies.

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Idiopathic Immunoneutropenia

Blood ◽

10.1182/blood.v9.6.632.632 ◽

1954 ◽

Vol 9 (6) ◽

pp. 632-641 ◽

Cited By ~ 15

Author(s):

JOHAN MÅRTENSSON ◽

INGA VIKBLADH

Keyword(s):

Bone Marrow ◽

Case Report ◽

Erythrocyte Sedimentation Rate ◽

Serum Protein ◽

Sedimentation Rate ◽

Total Protein ◽

Protein Fraction ◽

Globulin Fraction ◽

Erythrocyte Sedimentation ◽

Number Of Patients

Abstract A case report is presented of a woman, aged 49, with persistent neutropenia, increased erythrocyte sedimentation rate, a pathologic serum protein fraction migrating at the same rate as γ-globulin representing about 30 per cent of the total protein, and with undue fatigue as the only symptom. Normal leukocytes, especially neutrophils, were agglutinated by a factor contained in the patient’s serum and bound to the pathologic γ-globulin fraction and active even in a dilution of at least 1:120. The neutropenia may be explained by the formation, in the patient, of antibodies intravascularly agglutinating her own neutrophile leukocytes, which were then eliminated from the circulating blood. The appearance of the bone marrow did not argue against such an assumption. It has not been possible to demonstrate any definite causal factor of the disease. As far as the neutrophile leukocytes are concerned, the disease is analogous with idiopathic immunohemolytic anemia and idiopathic immunothrombocytopenia. No leukocyte agglutination could be demonstrated in sera from two other patients with granulocytopenia or in sera from a number of patients with various diseases and associated increased γ-globulin.

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THE VALUE OF ERYTHROCYTE SEDIMENTATION RATE AS SCREENING TEST IN HOSPITALIZED PATIENTS

Medical Connections ◽

10.33311/medcon.2009.11.3.2 ◽

2009 ◽

Vol 11 (3/2009) ◽

Keyword(s):

Erythrocyte Sedimentation Rate ◽

Sedimentation Rate ◽

Screening Test ◽

Hospitalized Patients ◽

Erythrocyte Sedimentation

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