scholarly journals Pyemotes Species Isolated from Sputum Sample of COVID-19 patient- A Case Report

2021 ◽  
Vol 4 (1) ◽  
pp. 61-63
Author(s):  
Kishor Gurung ◽  
Prabesh Pant ◽  
Sandeep Pokhrel ◽  
Rohit Shah ◽  
Dhanraj Neupane ◽  
...  

COVID-19, which emerged as a new and unknown disease in December of 2019, has transformed into a full-blown pandemic. It has affected all spheres of life, however, has claimed more lives of immune-compromised. Many opportunistic infections are being reported. We present a case of pyemotes species in sputum sample of a COVID-19 patient

Author(s):  
Humsheer Singh Sethi ◽  
Kamal Kumar Sen ◽  
Sudhansu Sekhar Mohanty ◽  
Sangram Panda ◽  
Kolluru Radha Krishna ◽  
...  

Abstract Background There has been a rapid rise in the number of COVID-19-associated rhino-orbital mucormycosis (CAROM) cases especially in South Asian countries, to an extent that it has been considered an epidemic among the COVID-19 patients in India. As of May 13, 2021, 101 CAROM cases have been reported, of which 82 cases were from India and 19 from the rest of the world. On the other hand, pulmonary mucormycosis associated with COVID-19 has a much lesser reported incidence of only 7% of the total COVID-19-associated mucormycosis cases (Singh AK, Singh R, Joshi SR, Misra A, Diab Metab Syndr: Clin Res Rev, 2021). This case report attempts to familiarize the health care professionals and radiologists with the imaging findings that should alarm for follow-up and treatment in the lines of CAROM. Case presentation Rhino-orbital mucormycosis (ROM) is a manifestation of mucormycosis that is thought to be acquired by inhalation of fungal spores into the paranasal sinuses. Here, we describe a 55-year-old male, post COVID-19 status with long standing diabetes who received steroids and ventilator therapy for the management of the viral infection. Post discharge from the COVID-19 isolation ICU, the patient complained of grayish discharge from the right nostril and was readmitted to the hospital for the nasal discharge. After thorough radiological and pathological investigation, the patient was diagnosed with CAROM and managed. Conclusion Uncontrolled diabetes and imprudent use of steroids are both contributing factors in the increased number of CAROM cases. Our report emphasizes on the radiological aspect of CAROM and reinforces the importance of follow-up imaging in post COVID-19 infection cases with a strong suspicion of opportunistic infections.


2017 ◽  
Vol 23 (2) ◽  
pp. 297-299 ◽  
Author(s):  
Adam F Carpenter ◽  
Shikha J Goodwin ◽  
Peter F Bornstein ◽  
Andrew J Larson ◽  
Christine K Markus

Background: Fingolimod is an oral disease-modifying therapy for relapsing forms of multiple sclerosis, which acts by sequestering lymphocytes within lymph nodes. Objective: To describe a case of extrapulmonary cryptococcosis in a patient taking fingolimod. Methods: Case report. Results: A 47-year-old man developed a non-healing skin lesion approximately 16 months after starting treatment with fingolimod. Biopsy revealed cryptococcosis. Fingolimod was discontinued and the lesion resolved with antifungal therapy. Conclusion: Despite few reported opportunistic infections in the pivotal clinical trials and first few years post-marketing, there has been a recent increase in reported AIDS-defining illnesses in patients taking fingolimod. Neurologists should be alert for opportunistic infections in their patients using this medication.


2021 ◽  
Author(s):  
S. Gayenur Buyukberber ◽  
Ipek Mumcuoglu ◽  
B.Orkun Ozbay ◽  
Adalet Aypak ◽  
Bedia Dinc

Abstract Comamonas testosteroni is a Gram- negative, aerobic, motile, non-spore-forming bacillus. It has not been recognized as a component of the endogenous human microflora. Due to its ability to survive in liquid environments, it can survive for a long time in a hospital environment and cause opportunistic infections. Although rare, C. testosteroni has been reported as a cause of cellulitis, peritonitis, endocarditis, meningitis, endophthalmitis, tenosynovitis, pneumonia and bacteremia. Here, we present a case of a 4-year-old girl who was operated on for persistent cloaca with C. testosteroni isolated in her urine culture. Identification studies were performed by MALDI-TOF MS (bioMerieux, France) mass spectrophotometer method. Antibiotic susceptibility tests were performed with the automatic device VITEK-2 Compact (bioMérieux, France). Microorganism was found susceptible to ceftazidime and ciprofloxacin; intermediate susceptible to meropenem and piperacillin / tazobactam and resistant to gentamicin, amikacin, imipenem and trimethoprim-sulfamethoxazole. With this case report, C. testosteroni was reported as the first cause of urinary tract infection in our country and the third in the world.


2021 ◽  
Author(s):  
Joao Paste Silva ◽  
Catarina Secundino ◽  
Tiago Timotio ◽  
Aurea Angelica Paste

Context: Cryptococcosis is an important fungal infection that, after AIDS development globally, became more common, being an important cause of opportunistic infections. The pathogen normally gets in through the lungs, causes pulmonary infection and then spreads to another systems, particularly the nervous system in most cases. Along the clinical manifestation there was headache, fever, cranial neuropathies, altered mentation, lethargy, memory loss, and signals of meningeal irritation. Case-Report: A 48-year-old male patient with a one-year story of paraparesis in both legs, associated with pain, paresthesia, and progressive worsening to complete walking incapability, seeks medical consultation. Cerebrospinal fluid was turbid appearance, yellow colored, presence of RBC (1.239 cel/mm³) and leukocytes (149 cel/mm³ - 5% neutrophils, 91% lymphocytes and 4% monocytes), glucose of 23 mg/dL, chlorine of 96 mmol/L, and Cryptococcus neoformans was isolated. Immunosuppressive disease wasn´t found. In MRI, there were nodular images in the intradural and extradural sites through T11-T12 levels, compressing the spinal cord. Local biopsy revealed chronic granulomatous inflammatory process, consistent with the cryptococcosis suspect. Conclusions: The case represents an unusual manifestation of cryptococcosis, with an uncommon topography and profile, once it´s manifestation medullary and in a healthy individual is rare. The main differential diagnosis was spinal tuberculosis, an also rare disease yet with similar symptoms and relevant local epidemiology. To reach the diagnosis, laboratory study was necessary. The treatment was the same of cryptococcosis in general.


2019 ◽  
Vol 21 (6) ◽  
pp. 275-280 ◽  
Author(s):  
Rohini D. Samudralwar ◽  
Andrej Spec ◽  
Anne H. Cross

Abstract The use of immunomodulatory and immunosuppressive therapies in multiple sclerosis (MS) has allowed practitioners to regulate MS disease activity, with the caveat that these potent medications may render patients susceptible to opportunistic infections. The approval of fingolimod presented the first oral option for relapsing MS. Since 2015, postmarketing safety data have documented several published cases of cryptococcal meningitis and disseminated cryptococcosis associated with fingolimod use. However, surveillance mechanisms for opportunistic infections and management of active demyelinating disease with ongoing infection have not been adequately addressed. We present a case of isolated pulmonary cryptococcosis with the use of fingolimod to highlight the hurdles in balancing efficacious disease-modifying therapies for MS while treating an opportunistic infection associated with that therapy.


2020 ◽  
Vol 31 (12) ◽  
pp. 1222-1224
Author(s):  
Mauro Bertolini ◽  
María Felicitas Mutti ◽  
José AE Barletta ◽  
Adriana Falak ◽  
Daniel Cuatz ◽  
...  

Limited information is available concerning the coexistence of COVID-19 and opportunistic infections in people living with HIV. The possible association of COVID-19 with AIDS-related respiratory diseases should be considered, particularly in patients with advance immunosuppression. We report the case of a male patient with AIDS-related disseminated histoplasmosis associated with COVID-19.


2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Morgan S. Martin ◽  
Alison A. Smith ◽  
Monica Lobo ◽  
Anil S. Paramesh

Background. We describe the unusual case of a recently transplanted cadaveric renal transplant recipient who presented with recurrent pulmonary mucormycosis. Case Report. An 18-year-old man with end stage renal disease secondary to congenital renal agenesis status after cadaveric kidney transplant 4 months before presented with acute onset of fever, hemoptysis, and back pain. The patient underwent an emergent left lower lobectomy due to the critical nature of his illness. He was also treated with amphotericin with resolution of his symptoms. One week later, he had evidence of recurrent disease on imaging with a surgical site infection. He underwent reexploration with evacuation of an empyema and debridement of a surgical site infection. He was continued on IV antifungal therapy with isavuconazonium and amphotericin. Radiographic clearance of disease with three months of treatment was apparent with no evidence of recurrence at seven-month follow-up. Discussion. Opportunistic infections in solid organ transplant patients represent a significant source of morbidity and mortality. Most patients are treated with prophylactic anti-infective agents. However, rare infections such as pulmonary mucormycosis remain a risk. The transplant physician must be aware of these uncommon infections and their treatment strategies, including the management of uncommon recurrent disease.


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