Maternal and fetal factors contributing to neonatal outcome in Al-Tibri Medical College and Hospital

2021 ◽  
Vol 15 (1) ◽  
pp. 18-22
Author(s):  
Erum Saboohi ◽  
Nighat Seema ◽  
Abdulah Hadi Hassan
Keyword(s):  
Risk Factors ◽  
Antenatal Care ◽  
Preterm Delivery ◽  
Neonatal Outcome ◽  
Neonatal Outcomes ◽  
P Value ◽  
Medical College ◽  
Adverse Neonatal Outcome ◽  
Adverse Neonatal Outcomes ◽  
Nicu Admission

Background: The study was done to identify the maternal and fetal factors contributing to neonatal outcome and to evaluate the correlation between risk factors and adverse neonatal outcome. Subjects and methods: This prospective observational study was conducted on 126 mothers and their neonates fulfilling the selection criteria at Al-Tibri Medical College and Hospital. A self-designed Performa was used to enter data of subjects. Sick neonates were referred to neonatal intensive care unit for admission and management. The results were analyzed by using SPSS version 22. A p-values <0.05 was considered as significant. Results: Out of 126 enrolled subjects, 81% mothers were multigravidas, 31% were unbooked, 13.5% had gestational comorbidities, 15% were drug addict, 2% were Hepatitis B positive. 22.2% underwent emergency LSCS while 31.7% delivered babies by elective LSCS. Regarding fetal factors contributing to sick babies, IUGR (20%), twin fetuses (15.4%), prematurity (47.7%) were significant. 65 were sick babies. Adverse neonatal outcomes observed were prematurity in 25.4%, IUGR in 11.1%, NICU admission in 33.3%, and neonatal death in 2%. Risk factors associated with adverse neonatal outcomes were positive maternal drug addiction (p-value = 0.028), preterm delivery (p-value<0.001), NICU admission (p-value<0.001) and low birth weight (p-value <0.001). Conclusion: Compromised maternal antenatal care has profound deleterious effect on fetus and neonate. Obstetricians, perinatologists and neonatologists need to work in concord to improve maternal antenatal care hence improving neonatal outcome. In our study adverse neonatal outcome was associated with unbooked cases, delivery by EmLSCS, addicted mother, preterm delivery, LBW and neonates requiring NICU admission.

scholarly journals The Burden of Adverse Neonatal Outcome among Antenatal Substance Users in Ethiopia: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 8 ◽  
pp. 2333794X2110196
Author(s):  
Wubet Alebachew Bayih ◽  
Metadel Yibeltal Ayalew ◽  
Melaku Tadege ◽  
Maru Mekie ◽  
Teklehaimanot Kiros ◽  
...  
Keyword(s):  
Neonatal Outcome ◽  
Birth Outcome ◽  
Meta Analysis ◽  
Neonatal Outcomes ◽  
Data Bases ◽  
Substance Users ◽  
Adverse Neonatal Outcome ◽  
Pooled Prevalence ◽  
Adverse Neonatal Outcomes ◽  
International Data

Background. Substances mainly khat, alcohol and cigarette are used during pregnancy in Ethiopia. However, to this date, there is no pooled evidence about the burden of adverse neonatal outcomes among the substance users during pregnancy in the country. Methods. Eligible primary studies were accessed from 4 international data bases (Google Scholar, Science Direct, Scopus, and PubMed). The required data were extracted from these studies and then exported to stata version 14 for analysis. Subgroup analyses were conducted for evidence of heterogeneity. Results. A total of 2298 neonates were included from 7 studies. Among these neonates, 530(23.06%) were those whose mothers used substance during pregnancy (exposed group) whereas 1768 neonates were those whose mothers didn’t use substance during pregnancy (controls group). The pooled prevalence of adverse neonatal outcome among the exposed mothers was 38.32% (95% CI: 29.48%, 47.16%; I2 = 76.3%) whereas it was 16.29% (95% CI: 9.45%, 23.13%) among the controls. Adverse neonatal outcome was most burdensome among cigarette smokers 45.20% (95% CI: 37.68%, 52.73%; I2 = .00%) when compared with khat chewers 34.00% (95% CI: 20.87%, 47.13%) and alcohol drinkers 38.47% (95% CI: 17.96%, 58.98%). Low birth weight 42.00% (95% CI: 18.01%, 65.99%; I2 = 91.8%) was the most common adverse birth outcome. Conclusion. It was found that adverse neonatal outcomes were much more burdensome among antenatal substance users than the controls. Therefore, mothers should be enabled to quit using substance before pregnancy. Besides, strict comprehensive screening of every pregnant mother should be made at antenatal care clinics for early identification and management of antenatal substance use.

Predicting adverse neonatal outcomes in fetuses with abdominal wall defects using prenatal risk factors

2009 ◽  
Vol 201 (4) ◽  
pp. 383.e1-383.e6 ◽  
Author(s):  
Sara S. Nicholas ◽  
David M. Stamilio ◽  
Jeffery M. Dicke ◽  
Diana L. Gray ◽  
George A. Macones ◽  
...  
Keyword(s):  
Risk Factors ◽  
Abdominal Wall ◽  
Neonatal Outcomes ◽  
Abdominal Wall Defects ◽  
Prenatal Risk ◽  
Prenatal Risk Factors ◽  
Adverse Neonatal Outcomes

scholarly journals Metabolic Risk Factors and Outcomes in Acute Coronary Syndrome

2020 ◽  
pp. 46-50
Author(s):  
Ritu Attri ◽  
Harsimran Kaur ◽  
Raminderpal Singh Sibia ◽  
Mandip Singh Bhatia
Keyword(s):  
Risk Factors ◽  
Acute Coronary Syndrome ◽  
Positive Family History ◽  
Developed Countries ◽  
P Value ◽  
Health Crisis ◽  
Female Ratio ◽  
Medical College ◽  
Coronary Syndrome ◽  
History Of

Introduction: CAD is the most common cause of mortality in India. It is a common multifarious public health crisis today and a leading cause of morbidity and mortality in both developing and developed countries. Hence, understanding the predominant risk factors among the Indian population is important. Materials and Methods: This was a hospital based age and sex matched case control study, carried out at Government Medical College and Rajindra Hospital Patiala. A total of 100 patients of Acute coronary syndrome were studied. Patients and controls were enquired about  the presence of cardiometabolic risk factors and the significance of association of these risk factors with the occurrence of Acute coronary syndrome was given by p value of  <0.05. Results: Majority of the cases were in the age group 61-70 years (32%) with male to female ratio  of 1.25:1. Significant association was found between ACS and risk factors like smoking, positive family history of IHD, hypertension, diabetes, dyslipidemia, waist hip ratio and body mass index. Overall, most common outcome of ACS in the present study was NSTEMI (45%) followed by STEMI (35%) followed by Unstable angina (20%). Conclusion: Significant association was found between smoking and occurrence of STEMI and significant association was found between Hypertension and occurrence of NSTEMI.

scholarly journals The implications for advanced maternal age on pregnancy complications and adverse neonatal outcomes

2021 ◽  
Vol 29 (3) ◽  
pp. 200-209
Author(s):  
Zeynep Gedik Özköse ◽  
Süleyman Cemil Oğlak
Keyword(s):  
Birth Weight ◽  
Cesarean Section ◽  
Pregnancy Outcomes ◽  
Maternal Age ◽  
Advanced Maternal Age ◽  
Neonatal Outcomes ◽  
Apgar Scores ◽  
Adverse Neonatal Outcomes ◽  
Adverse Pregnancy ◽  
Nicu Admission

Objective This study aimed to determine the effect of advanced maternal age (AMA) on maternal and neonatal outcomes in pregnant women aged ≥35 years compared with patients aged 30–34 years. Also, we aimed to analyze the risk estimates of potential confounders to identify whether these variables contributed to the development of adverse pregnancy outcomes or not. Methods This retrospective cohort study included 2284 pregnant women aged ≥35 years at the time of delivery who was delivered in a tertiary referral hospital from January 1, 2016, to December 31, 2020. We further classified these women into two subgroups: 35–39 years as early AMA (EAMA), and ≥40 years as very AMA (VAMA). Pregnancy complications and adverse neonatal outcomes were recorded. Results Compared to younger women, pregnant AMA women had significantly higher risks of complicated pregnancies, including a higher risk of gestational diabetes mellitus (GDM, p<0.001), polyhydramnios (p<0.001), cesarean section (p<0.001), stillbirths (p<0.001), major fetal abnormality (p<0.001), preterm delivery (p<0.001), lower birth weight (p<0.001), lower 5-minute Apgar scores (p<0.001), lower umbilical artery blood pH values (p<0.001), neonatal intensive care unit (NICU) admission (p<0.001), and length of NICU stay (p<0.001). Conclusion We found a strong and significant association between VAMA and adverse pregnancy outcomes, including an increased risk of GDM, polyhydramnios, cesarean section, and adverse neonatal outcomes, including a higher risk of stillbirths, preterm delivery, lower birth weight, lower 5-minute Apgar scores, and NICU admission.

scholarly journals Neonatal Outcome Among Adolescent and Adult Pregnancy in a Tertiary Care Center of Nepal

2018 ◽  
Vol 14 (2) ◽  
pp. 56-59
Author(s):  
Jyoti Adhikari ◽  
Shristi Kharel ◽  
Lalita Bahl ◽  
Deepal Poudel ◽  
Rajesh K.C.
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Preterm Delivery ◽  
Adolescent Mothers ◽  
Neonatal Outcome ◽  
Birth Asphyxia ◽  
Adolescent Mother ◽  
P Value ◽  
The Common ◽  
Mother Group

Background: Teenage pregnancy is a common public health problem worldwide which is detrimental to the health of mother and child and has long been considered a high-risk situation. The risk of low birth weight (LBW) and preterm delivery is particularly high among teenagers.Methods: A comparative study was conducted in Nepalgunj Medical College Teaching Hospital, Kohalpur during the period of July 2015 to June 2016. The study was carried out to compare the immediate neonatal outcome and morbidity pattern in neonates of 50 adolescent and 50 adult mothers.Results: In the present study, 84% belonged to adolescent mother group (17-19 years) whereas 50% belonged to adult mother group (20-23 years). Illiteracy was seen more in adolescent mothers (62%) and most were from rural areas (68%). The common immediate neonatal outcome found in adolescent and adult mothers were preterm delivery (96% vs. 52%; p value 0.001), low birth weight (LBW) (70% vs. 38%; p value 0.001). The common neonatal morbidities seen significantly high in neonates of adolescent mothers, viz: Neonatal sepsis (NNS)(54% vs. 20% p value <0.02), apnea (30% vs. 14% P value <0.02), neonatal jaundice(NNJ)(44% vs. 30% p value <0.01) while the other morbidities found were birth asphyxia (20% vs. 14%; p value <0.1), Respiratory distress syndrome (RDS) (36% vs. 24% p value<0.1), anemia (16% vs. 8%; p value <0.1), seizure (10% vs. 8%; p value <0.1), meconium aspiration syndrome (MAS) (6% vs. 18%; p value<0.1) and intrauterine growth retardation(IUGR)(22% vs. 20%; p value <0.5). Similarly mortality was found to be more in neonates of adolescent mothers (14% vs. 8%; p value <0.1).Conclusion: Adolescent pregnant mothers are at risk of having poor neonatal outcome and morbidities like NNS, NNJ, RDS, apnea, IUGR, birth asphyxia, anemia and seizure. JNGMC,  Vol. 14 No. 2 December 2016, Page: 56-59

scholarly journals Association of Serum Calcium with Acute Myocardial Infarction

2017 ◽  
Vol 8 (1) ◽  
pp. 16-20
Author(s):  
SN Chowdhury ◽  
N Sultana ◽  
AH Chowdhury ◽  
P Mazumder ◽  
N Sharmin ◽  
...  
Keyword(s):  
Risk Factors ◽  
Myocardial Infarction ◽  
Acute Myocardial Infarction ◽  
Serum Calcium ◽  
Calcium Level ◽  
Serum Calcium Level ◽  
Fasting Blood Glucose ◽  
P Value ◽  
Medical College ◽  
Student’S T

Acute myocardial infarction (AMI) is a leading cause of morbidity and mortality worldwide. The incidence of AMI is dependent on certain traditional predisposing risk factors. In addition to the traditional risk factors, raised serum calcium level is also being considered as an associated factor for AMI. The aim of the study is to evaluate the association of serum calcium level with acute myocardial infarction in a tertiary level hospital in Bangladesh. This case control study was conducted in the Department of Biochemistry, Dhaka Medical College, Dhaka from January 2013 to December 2013. In this study, 50 diagnosed cases of AMI and 50 age and sex matched apparently healthy subjects were selected from DMCH purposively according to the selection criteria. Blood pressure, height and weight were measured and BMI was calculated. Biochemical parameters- serum calcium and fasting blood glucose in two groups were estimated in mmol/l. Then serum calcium was compared between two groups to observe the association with AMI. Results were analyzed statistically in SPSS version 17.0. Unpaired student's 't'-test and Spearman correlation analysis was done. All the results were expressed as mean ±SD and p value <0.05 was accepted as level of significance. Present study showed that serum calcium level was significantly higher(p=.001) in cases (2.61±.15 mmol/l) when compared with that of controls (2.13±.15mmol/l). Serum calcium also showed a significant positive correlation with AMI (rho=0.858, p=0.001).Findings of study concludes that increased serum calcium is associated with AMI.Bangladesh J Med Biochem 2015; 8(1): 16-20

scholarly journals Faktor-Faktor Yang Mempengaruhi Kunjungan Antenatal Care Terhadap Perilaku Antenatal Care

2020 ◽  
Vol 1 (2) ◽  
pp. 67-76
Author(s):  
Puji Astuti Wiratmo ◽  
Lisnadiyanti ◽  
Nurkamilia Sopianah
Keyword(s):  
Risk Factors ◽  
Health Care ◽  
Antenatal Care ◽  
Pregnant Women ◽  
Family Support ◽  
Health Workers ◽  
P Value ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Correlation Design

Introduction: Antenatal Care (ANC) is an effort to detect the occurrence of high risk in pregnant women. However, ANC non-compliance was still found due to several factors. Aim of study: This study aims to determine factors that influence ANC visits to ANC behavior at Puskesmas Pasar Rebo East Jakarta. Method: This study used a descriptive correlation design with a cross-sectional survey. Data analysis used Spearman's rho with 117 respondents. Results and Discussion: The results showed that there are some factors that influence ANC visits to ANC behavior, including age with a correlation value (r = 0.419), a p-value of 0.000; education with a correlation value (r = 0.425), p-value of 0.000; jobs with a correlation value (r = 0.279), p-value of 0.002; income with a correlation value (r = 0.407), p-value of 0.000; knowledge with a correlation value (r = 0.409), p-value of 0.000; husband / family support with a correlation value (r = 0.417), p-value of 0.000; attitude with a correlation value (r = 0.597), p-value of 0.000 (<0.05). Irregularity in carrying out ANC has a bad impact on pregnant women because they are not aware of the risk factors that may occur to the mother and her fetus and can not be detected early on the disease suffered by pregnant women. Conclusion: The conclusion of this study is nurses as health workers need to increase their role as educators and health care provider to pregnant women and their families about the importance of ANC to reduce maternal mortality and monitor the state of the fetus.

scholarly journals Foetomaternal outcome in multifoetal pregnancy in a tertiary rural teaching hospital

2021 ◽  
Vol 10 (2) ◽  
pp. 614
Author(s):  
Sneha Gond ◽  
Partha Pratim Sharma ◽  
Narra Madhuri ◽  
Kasturi Barman
Keyword(s):  
Prospective Observational Study ◽  
Statistical Significance ◽  
P Value ◽  
Statistical Association ◽  
Maternal Complications ◽  
Chi Square ◽  
Medical College ◽  
Chi Square Test ◽  
Nicu Admission ◽  
Rural Teaching

Background: Aim of the study was to find out foeto-maternal outcome of multifoetal pregnancy in relation to chorionicity and to analyse the associated risk factors.Methods: This study was a prospective observational study on multifoetal pregnancy conducted at Midnapore medical college and hospital. Statistical analysis was done by chi-square test and statistical significance was set at p-value<0.05.Results: Incidence of multifoetal pregnancy was 1.7%. Modal age group was 20-24 years age and 82% conceived spontaneously. Among chorionicity, Dichorionic diamniotic (DCDA) were 60% followed by 34% Monochorionic diamniotic (MCDA), 4% Monochorionic monoamniotic (MCMA) and 2% Trichorionic triamniotic (TCTA). Among maternal complications preterm labour were present in both twins and triplets followed by anemia. LSCS was required in 60.8 % of twins and common indication was malpresentation. Majority of MC and TC were delivered at gestational age of 31-33 weeks (47.1% MCDA, 50% MCMA and 60% TCTA) and dichorionic delivered at 34-36 week (48.7%). Statistical association between neonatal outcomes and chorionicity were significant in IUGR (p=<0.0001), stillbirth (p=0.0356), congenital anomalies (p=0.0017), discordant growth (p<0.0001), Apgar score <7 (p<0.0001), low birth weight (p=0.014), live birth (p≤0.0001) and NICU admission (p<0.0001).Conclusions: Maternal and perinatal outcome was significant in monochorionic and trichorionic pregnancies compared to dichorionic pregnancies with increased NICU admissions required in monochorionic and trichorionic gestations.

scholarly journals Intrauterine Foetal Death: A Hospital Based Study

2022 ◽  
Vol 19 (1) ◽  
pp. 89-91
Author(s):  
Kamar Jahan ◽  
Binod Kumar Mahaseth
Keyword(s):  
Risk Factors ◽  
Antenatal Care ◽  
Fetal Death ◽  
Well Being ◽  
Intrauterine Fetal Death ◽  
Exclusion Criterion ◽  
Foetal Death ◽  
Medical College ◽  
Associated Risk Factors ◽  
Age Range

Introduction: Foetal death at any stage of pregnancy is not just a tragic event but also a more traumatic for the mental well-being of a mother. It is one of the most wrenching events in the field of obstetrics. Aims: The study was done to determine the probable risk factors of intrauterine foetal death and role of antenatal care in its prevention. Methods: The study was conducted  in Obstetrics and Gynecology department at Nepalgunj Medical college from July 2018 to July 2020 .Inclusion criteria were  intrauterine fetal death  of >28 weeks of gestation and baby weighing  1000 grams or more . An exclusion criterion was molar pregnancy. Results: There were 115(3.52%) intrauterine fetal death during the study period, making it 35 per 1000 cases. In 17(14.78%) the cause of intrauterine fetal death was not known. The other common associated risk factors were prematurity in 14(12.17%) and hypertension in 13(11.30%). Similarly anemia and antepartum hemorrhage were seen in 13(11.30%) each. 11(9.56%) patients had oligohydramnios. Mal presentation was found in 8(6.95%) patients while polyhydromnios in 6(5.21%).The commonest age range in whom intrauterine fetal death was seen was 20-30 (73.90%). 28 (24.34%) patients were at preterm pregnancy ranging between 28-30 weeks whereas 17(14.78) intrauterine fetal death occured at  32-34 weeks. 77 foetuses were preterm and their birth weight was between 1 - 1.5 kg  with the mean wt of  1175.73 gms. Conclusion: Intrauterine fetal death is still common inspite of the improving awareness in importance of regular antenatal care. In majority, the cause of intrauterine fetal death is still unknown. However, where the cause was known prematurity was the commonest.

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