scholarly journals Functional MRI Reveals Emotional Modulation of Pain Processing in the Human Cervical Spinal Cord and Brainstem

2018 ◽  
Vol 1 (1) ◽  
Author(s):  
McIver Theresa A ◽  
Kornelsen Jennifer ◽  
Stroman Patrick W
Keyword(s):  
Spinal Cord ◽  
Functional Mri ◽  
Cervical Spinal Cord ◽  
Pain Processing ◽  
Emotional Modulation

Limb-specific emotional modulation of cervical spinal cord neurons

2013 ◽  
Vol 13 (3) ◽  
pp. 464-472 ◽  
Author(s):  
Theresa A. McIver ◽  
Jennifer Kornelsen ◽  
Stephen D. Smith
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Emotional Modulation ◽  
Spinal Cord Neurons

SSFSE sequence functional MRI of the human cervical spinal cord with complex finger tapping

2009 ◽  
Vol 70 (1) ◽  
pp. 1-6 ◽  
Author(s):  
Chu-hai Xie ◽  
Kang-mei Kong ◽  
Ji-tian Guan ◽  
Ye-xi Chen ◽  
Jian-kang He ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Functional Mri ◽  
Cervical Spinal Cord ◽  
Finger Tapping

scholarly journals Neural Responses to Consciously and Unconsciously Perceived Emotional Faces: A Spinal fMRI Study

2018 ◽  
Vol 8 (8) ◽  
pp. 156 ◽  
Author(s):  
Alyssia Wilson ◽  
Tiffany Kolesar ◽  
Jennifer Kornelsen ◽  
Stephen Smith
Keyword(s):  
Spinal Cord ◽  
Cervical Spinal Cord ◽  
Spin Echo ◽  
Single Shot ◽  
Neural Responses ◽  
Emotional Modulation ◽  
Potential Threat ◽  
Emotional Faces ◽  
Fearful Faces ◽  
Spinal Fmri

Emotional stimuli modulate activity in brain areas related to attention, perception, and movement. Similar increases in neural activity have been detected in the spinal cord, suggesting that this understudied component of the central nervous system is an important part of our emotional responses. To date, previous studies of emotion-dependent spinal cord activity have utilized long presentations of complex emotional scenes. The current study differs from this research by (1) examining whether emotional faces will lead to enhanced spinal cord activity and (2) testing whether these stimuli require conscious perception to influence neural responses. Fifteen healthy undergraduate participants completed six spinal functional magnetic resonance imaging (fMRI) runs in which three one-minute blocks of fearful, angry, or neutral faces were interleaved with 40-s rest periods. In half of the runs, the faces were clearly visible while in the other half, the faces were displayed for only 17 ms. Spinal fMRI consisted of half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequences targeting the cervical spinal cord. The results indicated that consciously perceived faces expressing anger elicited significantly more activity than fearful or neutral faces in ventral (motoric) regions of the cervical spinal cord. When stimuli were presented below the threshold of conscious awareness, neutral faces elicited significantly more activity than angry or fearful faces. Together, these data suggest that the emotional modulation of spinal cord activity is most impactful when the stimuli are consciously perceived and imply a potential threat toward the observer.

Functional MRI of the cervical spinal cord on 1.5 T with fingertapping: to what extent is it feasible?

2006 ◽  
Vol 49 (1) ◽  
pp. 73-81 ◽  
Author(s):  
N. Govers ◽  
J. Béghin ◽  
J. W. M. Van Goethem ◽  
J. Michiels ◽  
L. van den Hauwe ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Functional Mri ◽  
Cervical Spinal Cord

Organization of the intrinsic functional network in the cervical spinal cord: A resting state functional MRI study

Neuroscience ◽  
2016 ◽  
Vol 336 ◽  
pp. 30-38 ◽  
Author(s):  
Xiaojia Liu ◽  
Fuqing Zhou ◽  
Xiang Li ◽  
Wenshu Qian ◽  
Jiaolong Cui ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Functional Mri ◽  
Resting State ◽  
Cervical Spinal Cord ◽  
Functional Network ◽  
Mri Study

Alterations in the number of motoneurons containing immunoreactive calcitonin gene-related peptide(CGRP)& choline acetyltransferase(ChAT) in the cervical spinal cord of the wobbler mouse during the development of the motoneuron disease

1995 ◽  
Vol 53 ◽  
pp. 970-971
Author(s):  
L. Vacca-Galloway ◽  
Y.Q. Zhang ◽  
P. Bose ◽  
S.H. Zhang
Keyword(s):  
Spinal Cord ◽  
Early Stage ◽  
Cervical Spinal Cord ◽  
Wild Type Mouse ◽  
Reflex Response ◽  
Mouse Strains ◽  
Behavioral Tests ◽  
Wobbler Mouse ◽  
Stage 4 ◽  
Stage 1

The Wobbler mouse (wr) has been studied as a model for inherited human motoneuron diseases (MNDs). Using behavioral tests for forelimb power, walking, climbing, and the “clasp-like reflex” response, the progress of the MND can be categorized into early (Stage 1, age 21 days) and late (Stage 4, age 3 months) stages. Age-and sex-matched normal phenotype littermates (NFR/wr) were used as controls (Stage 0), as well as mice from two related wild-type mouse strains: NFR/N and a C57BI/6N. Using behavioral tests, we also detected pre-symptomatic Wobblers at postnatal ages 7 and 14 days. The mice were anesthetized and perfusion-fixed for immunocytochemical (ICC) of CGRP and ChAT in the spinal cord (C3 to C5).Using computerized morphomety (Vidas, Zeiss), the numbers of IR-CGRP labelled motoneurons were significantly lower in 14 day old Wobbler specimens compared with the controls (Fig. 1). The same trend was observed at 21 days (Stage 1) and 3 months (Stage 4). The IR-CGRP-containing motoneurons in the Wobbler specimens declined progressively with age.

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