scholarly journals Monitoring the Effects of Combinatet Treatment Chronic Periodontitis Using Bone Metabolism Biomarker Osteocalcin

2020 ◽  
Vol 3 (2) ◽  
Author(s):  
Hakobyan Gagik ◽  
Yessayan Lazar ◽  
Khudaverdyan Margarita ◽  
Tunyan Gegam ◽  
Gyulamiryan Laura ◽  
...  
Pharmacia ◽  
2020 ◽  
Vol 67 (1) ◽  
pp. 1-4
Author(s):  
Iryna Yarmoshuk

One of the main mechanisms in pathogenesis of chronic periodontitis is disordered bone metabolism that is accomplished by cortical plate’s resorption, destruction of the interdental septums and osteoporosis of the jaws. Administration of osteotropic agents will allow achieving efficient results in treatment of the patients affected by periodontal disorders, lower the tendency of bone resorption and stimulate the processes of regeneration. The article demonstrates the results obtained after the surgical treatment of the patients with osteopenia affected by chronic periodontitis of II–III degree that were administered simultaneously with synthetic osteoplastic material Tricalcium phosphate and a bone resorption inhibitor Ibandronic acid. It has been established the high efficiency of the recommended treatment that was proved by positive progress of biochemical markers of bone metabolism in blood serum and urine of the individuals from the main group taken 24 month after the beginning of the treatment. The study shows that the reis arise of osteocalcin by 11,5% in the blood serum of the main group patients 2 years after the research and the amount of desoxypiridynolin, on the other hand, was by 21,72% lower comparing with those from the main group (р < 0,05).


2021 ◽  
Vol 18 (4) ◽  
pp. 610-614
Author(s):  
Shaili Pradhan ◽  
Shweta Agrawal

Background: Periodontitis is inflammatory disorder resulting in progressive destruction of the periodontal ligament and alveolar bone with pocket formation, recession, or both. Vitamin D has a benefit in bone metabolism and anti-inflammatory activity involving T-cell homeostasis. The objective of this study was to compare the vitamin D level in patient with chronic periodontitis and healthy periodontium and evaluate its correlation.Methods: A comparative cross-sectional study was done in 80 patients (40 with healthy periodontium and 40 with chronic periodontitis) visiting to Department of Dental Surgery (Periodontology and Oral Implantology Section) of Bir Hospital. Parameters measured were plaque index, gingival index, clinical attachment level and pocket depth for the evaluation of healthy periodontium and chronic periodontitis. Results: The result showed 16.58±6.65ng/mL and 19.06±11.52ng/mL level of vitamin D in female and male respectively (p-value 0.230) and 16.85±13.30 ng/mL and 19.78±5.87 ng/mL level of vitamin D in healthy and chronic periodontitis groups respectively (p-value 0.209).Conclusions: There are no differences in the level of serum vitamin D between healthy and chronic periodontitis groups. No association was seen between vitamin D level and chronic periodontitis.Keywords: Bone metabolism; chronic periodontitis; clinical attachment level; healthy periodontium; vitamin D; periodontal pocket


2014 ◽  
Vol 122 (03) ◽  
Author(s):  
V Seifert-Klauss ◽  
AC Ritzinger ◽  
B Lesoine ◽  
M Kiechle ◽  
M Schmidmayr ◽  
...  

Planta Medica ◽  
2015 ◽  
Vol 81 (16) ◽  
Author(s):  
M Makropoulou ◽  
C Karakasi ◽  
N Aligiannis ◽  
E Kalpoutzakis ◽  
AL Skaltsounis ◽  
...  
Keyword(s):  

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