scholarly journals A Patient of Crescentic Glomerulonephritis with Positive Anti Myeloperoxidase Antibodies and Immunoglobulin a Deposits on Immunofluorescence: The Conundrum Continues

2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Chawla Mayank ◽  
Hoon Tan Puay ◽  
Baikunje Shashidhar
2004 ◽  
Vol 41 (1) ◽  
pp. 44-49 ◽  
Author(s):  
J. T. Borda ◽  
D. R. Pauley ◽  
J. J. Mackey ◽  
X. Alvarez ◽  
M. A. Simon ◽  
...  

2009 ◽  
Vol 127 (3) ◽  
pp. 140-144 ◽  
Author(s):  
Luis Fernando Arias ◽  
Jorge Henao ◽  
Rubén Darío Giraldo ◽  
Nelson Carvajal ◽  
Joaquin Rodelo ◽  
...  

CONTEXT AND OBJECTIVE: Epidemiological data provide useful information for clinical practice and investigations. This study aimed to determine glomerular disease frequencies in a region of Colombia and it represents the basis for future studies. DESIGN AND SETTING: Single-center retrospective analysis at the University of Antioquia, Colombia. METHODS: All native renal biopsies (July 1998 to December 2007) were reviewed, but only glomerular diseases were analyzed. The diagnosis of each case was based on histological, immunopathological and clinical features. RESULTS: A total of 1,040 biopsies were included. In 302 cases (29.0%), the patient's age was < 15 years. Primary glomerular diseases were diagnosed in 828 biopsies (79.6%) and secondary in 212 (20.4%). The most common primary diseases were focal and segmental glomerulosclerosis (FSGS) (34.8%), immunoglobulin A (IgA) nephropathy (IgAN) (11.8%), membranous glomerulonephritis (MGN) (10.6%), minimal change disease (MCD) (10.6%), crescentic glomerulonephritis (GN) (5.6%), and non-IgA mesangial proliferative GN (5.6%). Postinfectious GN represented 10.7% of the diagnoses if included as primary GN. Lupus nephritis corresponded to 17.8% of the entire series. In adults, the order of the most frequent primary diseases was: FSGS, IgAN, MGN, crescentic GN and MCD. In children (< 15 years), the most frequent were: FSGS, postinfectious GN, MCD, non-IgA mesangial proliferative GN, endocapillary diffuse GN and IgAN. CONCLUSIONS: As among Afro-Americans, FSGS is the most frequent type of glomerulopathy in our population, but in our group, there are more cases of IgAN. The reasons for these findings are unclear. This information is an important contribution towards understanding the prevalence of renal diseases in Latin America.


Nephrology ◽  
2000 ◽  
Vol 5 (3) ◽  
pp. A98-A98
Author(s):  
Timoshanko Jr ◽  
Kitching Ar ◽  
Holdsworth Sr ◽  
Tipping PG.

2006 ◽  
Vol 12 (3) ◽  
pp. 148-151
Author(s):  
Noriko Ihara ◽  
Ikuo Murohashi ◽  
Masako Itho ◽  
Ikuo Amino ◽  
Katsuhiko Yoshida ◽  
...  

2017 ◽  
pp. 85-88
Author(s):  
O.I. Ostapenko ◽  
◽  
V.P. Kvashenko ◽  
I.K. Akimova ◽  
I.N. Nosova ◽  
...  

The objective: the study of immunomodulatory effects of a probiotic, which contains lyophilized Lactobacillus (Lactobacillus rhamnosus) – 13 mg (2,0ґ109 CFU) and lyophilized bifidobacteria (Bifidobacterium lactis) – 4 mg (2,0ґ109 CFU) the level of serum immunoglobulin IgA as a marker of local immunity in the plasma of women of reproductive age with the violation of the biocenosis of the vagina. Patients and methods. The study involved 86 patients of reproductive age with the violation of the vaginal biocenosis, which were divided into two groups according to received treatment. A survey was conducted for all patients in both groups: determine the level of serum IgA, measuring pH of vaginal environment and the quantification of lactobacilli and pathogenic flora with the help of test-system «Florotsenoz» before treatment and in 6 weeks after treatment. The state of vaginal microbiocenosis in both groups before treatment was homogeneous. Patients in both groups as therapy at the first stage of treatment received, if necessary antimicrobial therapy depending on the selected flora. In the second stage (restoration of microflora) patient of the main group received systemic probiotic combined with a complex prebiotic local action, patients in the control group, the probiotic localy in the form of the vaginal candles or tablets. Results. The research stated the increasing level of serum IgA in blood plasma of patients of the main group compared to control group at 20%, normalizing the pH of the vaginal environment in the main group in 94% of cases, which indicates an increase of immunity in mucosal. Conclusion. The inclusion of the systemic probiotic in the scheme of treatment of disorders of biocenosis of the vagina system enhances the increasing of immunity of the mucous membranes, and the vaginal tablets prebiotic of local action restores the own normal microflora of the vagina. Key words: serum immunoglobulin A, local immunity, vaginal dysbiosis, probiotics, prebiotics, vaginal microbiocenosis, the pH of the vaginal environment.


Author(s):  
Alper Alp ◽  
Hakan Akdam ◽  
Sabri Barutça ◽  
Nezih Meydan ◽  
Yavuz Yeniçerioğlu ◽  
...  

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