scholarly journals Dosimetric Implications of Number of Breathing Phases Used in the Definition of Internal Target Volume [ITV] in the Treatment of Non-Small Cell Lung Cancers Using Stereotactic Body Radiation Therapy (SBRT)

2019 ◽  
Vol 3 (1) ◽  
Author(s):  
Heard Von Darius ◽  
Bolookat Eftekhar Rajab ◽  
Martin Kate ◽  
Gomez Jorge ◽  
Singh Anurag K ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Target Volume ◽  
Small Cell ◽  
Internal Target ◽  
Small Cell Lung ◽  
Internal Target Volume ◽  
Lung Cancers ◽  
Stereotactic Body Radiation ◽  
Definition Of

scholarly journals Investigation of 4D dose in volumetric modulated arc therapy-based stereotactic body radiation therapy: does fractional dose or number of arcs matter?

2020 ◽  
Vol 61 (2) ◽  
pp. 325-334
Author(s):  
Takashi Shintani ◽  
Mitsuhiro Nakamura ◽  
Yukinori Matsuo ◽  
Yuki Miyabe ◽  
Nobutaka Mukumoto ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Volumetric Modulated Arc Therapy ◽  
Target Volume ◽  
Lung Tumors ◽  
Internal Target ◽  
Internal Target Volume ◽  
Stereotactic Body Radiation ◽  
Arc Therapy ◽  
Fractional Dose

Abstract The aim of this study was to assess the impact of fractional dose and the number of arcs on interplay effects when volumetric modulated arc therapy (VMAT) is used to treat lung tumors with large respiratory motions. A three (fractional dose of 4, 7.5 or 12.5 Gy) by two (number of arcs, one or two) VMAT plan was created for 10 lung cancer cases. The median 3D tumor motion was 17.9 mm (range: 8.2–27.2 mm). Ten phase-specific subplans were generated by calculating the dose on each respiratory phase computed tomography (CT) scan using temporally assigned VMAT arcs. We performed temporal assignment of VMAT arcs using respiratory information obtained from infrared markers placed on the abdomens of the patients during CT simulations. Each phase-specific dose distribution was deformed onto exhale phase CT scans using contour-based deformable image registration, and a 4D plan was created by dose accumulation. The gross tumor volume dose of each 4D plan (4D GTV dose) was compared with the internal target volume dose of the original plan (3D ITV dose). The near-minimum 4D GTV dose (D99%) was higher than the near-minimum 3D internal target volume (ITV) dose, whereas the near-maximum 4D GTV dose (D1%) was lower than the near-maximum 3D ITV dose. However, the difference was negligible, and thus the 4D GTV dose corresponded well with the 3D ITV dose, regardless of the fractional dose and number of arcs. Therefore, interplay effects were negligible in VMAT-based stereotactic body radiation therapy for lung tumors with large respiratory motions.

scholarly journals Reduced Margin Stereotactic Body Radiation Therapy for Early Stage Non-Small Cell Lung Cancers

Cureus ◽  
2020 ◽  
Author(s):  
Mayank Patel ◽  
Tyler Colvin ◽  
Robert Spencer Kirkland ◽  
Samuel Marcrom ◽  
Michael Dobelbower ◽  
...  
Keyword(s):  
Radiation Therapy ◽  
Stereotactic Body Radiation Therapy ◽  
Early Stage ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancers ◽  
Stereotactic Body Radiation
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