scholarly journals Radioisotope Guided Sentinel Lymph Node Dissection in Prostate Cancer: Rate of Lymph Node Involvement Depending on Preoperative Tumor Characteristics in More Than 2,100 Patients

2015 ◽  
Vol 1 (1) ◽  
pp. 1-4
Author(s):  
Alexander Winter ◽  
Svenja Engels ◽  
Marie-Christin Süykers ◽  
Rolf-Peter Henke ◽  
Friedhelm Wawroschek
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Dissection ◽  
Lymph Node Involvement ◽  
Sentinel Lymph Node Dissection ◽  
Tumor Characteristics ◽  
Node Dissection ◽  
Cancer Rate ◽  
Node Involvement

Laparoscopic Sentinel Lymph Node Dissection – A Novel Technique for the Staging of Prostate Cancer

2006 ◽  
Vol 49 (2) ◽  
pp. 280-285 ◽  
Author(s):  
Stefan Corvin ◽  
David Schilling ◽  
Kai Eichhorn ◽  
Ilse Hundt ◽  
Joerg Hennenlotter ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Dissection ◽  
Sentinel Lymph Node Dissection ◽  
Node Dissection ◽  
Novel Technique

scholarly journals Current perspectives of sentinel lymph node dissection at the time of radical surgery for prostate cancer

2016 ◽  
Vol 50 ◽  
pp. 228-239 ◽  
Author(s):  
Gavish Munbauhal ◽  
Thomas Seisen ◽  
Florie D. Gomez ◽  
Benoit Peyronnet ◽  
Olivier Cussenot ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Dissection ◽  
Radical Surgery ◽  
Sentinel Lymph Node Dissection ◽  
Node Dissection

scholarly journals Clinical Outcome of Patients with Lymph Node-Positive Prostate Cancer following Radical Prostatectomy and Extended Sentinel Lymph Node Dissection

2014 ◽  
Vol 94 (3) ◽  
pp. 296-306 ◽  
Author(s):  
Alexander Muck ◽  
Christian Langesberg ◽  
Michael Mugler ◽  
Jörg Rahnenführer ◽  
Bernd Wullich ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Clinical Outcome ◽  
Lymph Node Dissection ◽  
Radical Retropubic Prostatectomy ◽  
Sentinel Lymph Node Dissection ◽  
Node Dissection ◽  
Cancer Specific Survival ◽  
The Mean

Objective: This study sought to evaluate the clinical outcome after extended sentinel lymph node dissection (eSLND) and radical retropubic prostatectomy (RRP) in patients with clinically localized prostate cancer (PCa). Subjects and Methods: From August 2002 until February 2011, a total of 819 patients with clinically localized PCa, confirmed by biopsy, were treated with RRP plus eSLND. Biochemical recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS) were assessed with Kaplan-Meier curves. Various histopathological parameters were analyzed by univariate and multivariate analysis. Results: The mean follow-up was 5.3 years. Lymph node (LN) metastases occurred in 140 patients. We removed an average of 10.9 LNs via eSLND from patients with pN1 PCa. Postoperatively, 121 pN1 patients temporarily received adjuvant androgen deprivation therapy. The mean survival periods for RFS, RFS after secondary treatment, CSS, and OS were 4.7, 7.0, 8.8, and 8.1 years, respectively. The cancer-specific death rate of the 140 pN1 patients was 13.6%. RFS, CSS, and OS were significantly correlated with pathological margin status, LN density, the total diameter of evident metastases, and membership in the subgroup ‘micrometastases only'. Conclusion: Despite the presence of LN metastases, patients with a low nodal tumor burden demonstrate a remarkable clinical outcome after undergoing eSLND and RRP, thus suggesting a potential curative therapeutic approach.

What is the yield of regional lymph node dissection following sentinel lymph node involvement in patients with breast cancer?

2006 ◽  
Vol 24 (18_suppl) ◽  
pp. 10782-10782
Author(s):  
M. Ortega ◽  
M. Ruiz-Echarri ◽  
E. Prats ◽  
R. Lastra ◽  
E. Aguirre ◽  
...  
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Lymph Node Dissection ◽  
Regional Lymph Node ◽  
Tumour Size ◽  
Median Number ◽  
Lymph Node Involvement ◽  
Node Dissection ◽  
Regional Lymph Node Dissection ◽  
Node Involvement

10782 Background: Sentinel lymph node is a minimally invasive and accurate staging procedure for patients with invasive breast cancer. Histological SLN involvement with cancer cells requires regional lymph node dissection. Aim: To verify if subgroups of patients with sentinel lymph node involvement in which the risk of histological involvement of additional regional lymph nodes is minimal can be identified. Methods: Ninety six consecutive patients with invasive breast cancer and tumour size less than two centimeters by mammography, had lymphoscintigraphy with colloidal 99Tc and radioisotope-guided sentinel lymph node biopsy in the University Hospital of Zaragoza from 1999 to 2005.Pathological assessment included serial sections of the sentinel lymph node with inmunohistochemistry for cytokeratins in selected cases.39 patients had histological involvement and are presented in this analysis. Results: All 39 patients were females. Median tumour size was 20 mm (range 5–52) Median number of resected sentinel lymph node was 2 (range 1–5) Median number of involved sentinel lymph node was 1 (range 1–4) Regional lymph node dissection was performed in all patients (Axillary dissection in 31; internal mammary dissection in 1, both in 7). Median number of nodes was 13 (range 2–34) At least 1 additional involved lymph node was found in 19 patients (48%) We have correlated patient age, menopausal status, pathological tumour size, histological grade, estrogen receptors, progesterone receptors and Her2 with the risk of histological lymph node involvement in regional lymph node dissection. Conclusions: Tumour size was significantly associated to such risk: No significant financial relationships to disclose.

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