Management of Residual Psoriasis in Patients on Biologic Treatment

2020 ◽  
Vol 19 (2) ◽  
pp. 188-194
Author(s):  
Wasim Haidari ◽  
Adrian Pona ◽  
Steven Feldman
Keyword(s):  
2018 ◽  
Vol 2 ◽  
pp. S13
Author(s):  
Jashin J Wu ◽  
Minyi Lu ◽  
Karen A Veverka ◽  
Maartje Smulders ◽  
Eros Papademetriou ◽  
...  

Abstract not available. Disclosures: Study sponssored by LEO Pharma. Copyright 2018 SKIN


2020 ◽  
pp. flgastro-2020-101563
Author(s):  
Stephanie Shields ◽  
Allan Dunlop ◽  
John Paul Seenan ◽  
Jonathan Macdonald

COVID-19 has dominated life in 2020 with, at the time of writing, over 4.9M global cases and >320 000 deaths. The impact has been most intensely felt in acute and critical care environments. However, with most UK elective work postponed, laboratory testing of faecal calprotectin halted due to potential risk of viral transmission and non-emergency endoscopies and surgeries cancelled, the secondary impact on chronic illnesses such as inflammatory bowel disease (IBD) is becoming apparent. Data from the Scottish Biologic Therapeutic Drug Monitoring (TDM) service shows a dramatic drop in TDM testing since the pandemic onset. April 2020 saw a 75.6% reduction in adalimumab testing and a 36.2% reduction in infliximab testing when compared with February 2020 data, a reduction coinciding with the widespread cancellation of outpatient and elective activity. It is feared that disruption to normal patterns of care and disease monitoring of biologic patients could increase the risk of disease flare and adverse clinical outcomes. Urgent changes in clinical practice have been instigated to mitigate the effects of the pandemic on routine clinical care. Further transformations are needed to maintain safe, effective, patient-centred IBD care in the future.


2015 ◽  
pp. 777 ◽  
Author(s):  
Mingliang Zhang ◽  
Susan Brenneman ◽  
Chureen Carter ◽  
Breanna Essoi ◽  
Kamyar Farahi ◽  
...  

2021 ◽  
Author(s):  
Daniel Sumpton ◽  
Ayano Kelly ◽  
Jonathan C. Craig ◽  
Geraldine Hassett ◽  
Barry Kane ◽  
...  

2021 ◽  
Author(s):  
Witold Owczarek ◽  
Maciej Dzik ◽  
Joanna Narbutt ◽  
Irena Walecka ◽  
Marta Kowalczyk

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Yiting Wang ◽  
Rupa Makadia ◽  
Christopher Knoll ◽  
Jill Hardin ◽  
Erica A. Voss ◽  
...  

Abstract Background There has been a more pronounced shift toward earlier, more aggressive therapies in Crohn’s disease than in ulcerative colitis (UC). The aim of this study was to describe the pre-biologic treatment and health care experience, including co-morbidities and overall health care utilization, for UC patients who initiated biologic therapies, in the 5 years prior to the initiation of the first biologic agent. Methods UC patients who initiated a biologic agent approved for UC between 9/15/2005 and 1/30/2018 were identified from the IBM® MarketScan® Commercial Database, a large US database. The date of the first recorded UC biologic exposure was defined as the index date, and ≥ 5 years of pre-index records were required to evaluate patients’ treatment, disease progression and overall health care utilization prior to initiating biologic agents. Results Among the 1891 eligible patients, treatment with oral corticosteroids, 5-aminosalicylates, and other non-biologic immunomodulators, all increased progressively across the 5 years prior to the index. From within year-five to within year-one prior to the index, the median duration of oral corticosteroid treatment increased from 34 to 88 days per year and the proportion of patients who experienced more extensive/pancolitis disease increased from 16 to 59%. Overall, the frequency of all-cause health care visits also increased. Conclusions Patients with UC experienced increasing morbidity and treatment burden in the 5 years prior to initiating biologic therapy. To achieve reduced corticosteroids in UC management, better risk stratification is needed to help identify patients for more timely biologic treatment.


2017 ◽  
Vol 38 (1) ◽  
pp. 153-160 ◽  
Author(s):  
Elena Tronconi ◽  
Angela Miniaci ◽  
Michelangelo Baldazzi ◽  
Laura Greco ◽  
Andrea Pession

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