scholarly journals INFLUENCE OF ADVERSE PRODUCTION FACTORS ON CEREBRAL HEMODYNAMIC IN LOCOMOTIVE DRIVERS

2020 ◽  
Vol 73 (12) ◽  
pp. 2617-2622
Author(s):  
Olha M. Arustamian ◽  
Volodymyr S. Tkachyshyn ◽  
Vitalii E. Kondratiuk ◽  
Nataliia Yu. Tkachyshyna ◽  
Oleksandr Yu. Aleksiichuk ◽  
...  

The aim: To investigate the pathological changes in intra- and extra cranial blood vessels in workers of locomotive crews depending on their length of service. Materials and methods: The study involved 249 male patients, aged from 21 to 60 years who worked as locomotive drivers. We used Doppler examination and studied Doppler Indexes of cerebral vessels. Results: Results of examination showed that with increasing length of work of workers of locomotive crews (together with increasing of their age) we have established: 1) Reduction the elasticity of blood vessels (77.6% of the patients); 2) Increased violation of venous circulation (86.4%); 3) Reduced blood flow in the basilar artery (64%); 4) Reduced blood flow in the right and left vertebral arteries (65.6% and 65.5% respectively); 5) Increase in the thickness of intimate / media complex more than 1.1 in 62 % of drivers. All of that also connected with length of their work. Conclusions: we founded that speed of blood flow and elasticity in intra- and extra cranial vessels reduced with increase the length of service of workers of locomotive crews. Also we received such results: increasing violation of venous circulation, reducing blood flow in the basilar artery and reducing of blood flow in right and left vertebral arteries, increase intima / media thicknesses greater than 1,1 in locomotive drivers.

2009 ◽  
Vol 54 (No. 11) ◽  
pp. 537-542 ◽  
Author(s):  
A. Aydin ◽  
S. Yilmaz ◽  
Z.E. Ozkan ◽  
R. Ilgun

In this study, the circulus arteriosus cerebri of the ground squirrel (<i>Spermophilus citellus</i>) was investigated. Five ground squirrels were used as subjects. Coloured latex was injected from the left ventriculi of the hearts of all the squirrels. When the vertebral arteries of two of the animals were ligatured, it was found that there was no internal carotid artery. After careful dissection, the circulus arteriosus cerebri (the circle of Willis) was investigated. The right and left vertebral arteries gave rise to the caudal cerebellar artery before forming the basilar artery. The basilar artery formed the caudal communicans artery that was the caudal part of the circulus arteriosus cerebri on the pontocrural groove (sulcus pontocruralis). The caudal, medial, rostral cerebellar, the common root formed by the caudal cerebral and choroid arteries, the rostral choroid, the rostral and medial cerebral arteries arose from the vertebral, basilar and caudal communicans arteries and dispersed to the cerebrum and cerebellum from caudal to cranial. The termination and the branches of the rostral cerebral artery in ground squirrels varied. It was observed that the internal carotid artery does not supply the circulus arteriosus cerebri in ground squirrels.


Author(s):  
Krzysztof Jozwik ◽  
Damian Obidowski

Vertebral arteries are a system of two blood vessels through which blood is carried to the rear region of the brain. This region of the human body has to be very well supplied with blood, without any breaks or deficiencies in the blood flow. Blood is delivered to the brain through carotid arteries as well. All these arteries are connected to the circle of Willis, which has to fulfill all demands of the human brain as far as the blood flow is concerned. However, vertebral arteries due to their position and shape are a special kind of blood vessels. They originate at various distances from the aortic ostium, may branch off at different angles, have various length, inner diameter and spatial shape. Three different geometries of vertebral arteries, which most frequently occur in the human body structure, have been chosen, and for each twenty five various combinations of artery inner diameters have been used to generate 3D models of these arteries. For seventy five different models thus created, the numerical simulations have been performed. The results obtained have indicated explicitly that differences in the flow and instantaneous velocity values in vertebral arteries and in the point they join to form the basilar artery do not result from pathological changes in the artery system, but may follow from physical phenomena that occur in arteries as a consequence of the pulsating character of the flow and the unique geometry, which is related to the individual human anatomical structure.


Author(s):  
T V Zakhmatova ◽  
V V Shchedrenok ◽  
O V Moguchaya

Among 350 surveyed deformations of internal carotid arteries revealed in 38.6% of cases. At pathological deformation observed acceleration of flow speed indicators from 55% to 65% in part of tortuosity, average value of systolic speeds of a blood flow was 166±28.3 cm/s at the left and 174±30.2 cm/s at the right side. In vertical position in 31.6% of cases at pathological deformation observed transfor mation of tortuosity form. deformation corners became blunt, the gradient of flow speed indicators decreased or was absent, in some cases course of internal carotid arteries became rectilinear. Artificial deformations of vertebral arteries course revealed in 79.4% of people, average value of systolic speed of a blood flow was 92±15.3 cm/s at the left and 76±12.5 cm/s at the right side. In vertical position in deformations of the vertebral arteries, which carried to pathological, in 28.8% of cases a form of deformation was transformed to unpathological tortuosity. duplex sonography in vertical position in patients with tortuosity discovered new approaches in diagnostics of pathological deformations and defines indications to operative treatment.


2021 ◽  
Author(s):  
HuiHua Hu ◽  
XiaoCong Wang

Abstract Background: Brain stem infarction and pulmonary embolism are both serious life-threatening diseases with extremely high mortality. Central respiratory failure caused bycerebral stem infarction was considered in the initial stage of the disease. Pulmonary embolism (trunk) may have been the second cause of respiratory failure during diagnosis and treatment. The patient improved obviously after active treatment. Although the patient's condition improved significantly after active treatment, it is worth reflecting that if we had detected the right main pulmonary embolism in a timely manner during the first CTA examination, we could have determined whether the patient could benefit more from thrombolysis of the right main pulmonary artery under interventional therapy. Therefore, in clinical work, we should consider the possible complications ofthe patient while focusing on the most life-threatening primary disease.Case presentation:The patient, a 53-year-old female, she was immediately transferred from the emergency department to the ICU. Physical examination: T 37°C, HR 109/min, R 10/min, BP 105/73 mmHg, SpO 2 79%, GCS score 5, E1V2M2, coma. T CTA examination of the cervical blood vessels and cerebral blood vessels was recommended. 2) CTA examination of the cervical blood vessels and craniocerebral blood vessels performed at 10 o'clock on March 23 suggested moderate and severe stenosis at the beginning of the right vertebral artery, severe stenosis at the middle and upper segments of the basilar artery, and severe stenosis at the beginning of the bilateral posterior cerebral artery. Consideration: high possibility of brainstem infarction. After discussion with the family members, they agreed to submit the patient to percutaneous craniography and thrombectomy. 3) Cerebral artery extraction was performed from 23:50 on March 23 to 01:20 on March 24. Intraoperative diagnosis: 1. Cerebral stem infarction. 2. Upper basilar artery occlusion. Postoperative angiography showed that the basilar artery was unobstructed, and the bilateral superior cerebellar artery and posterior cerebral artery had returned to normal. Tirofiban was given 4 ml/h postoperatively. 4) The CT diagnosis room on March 24 reported the results of the vascular CTA scan from 10 'clock on March 23: A filling defect of the right main pulmonary artery and the left lower pulmonary artery lumen was observed. Pulmonary embolism was considered. Color Doppler ultrasound examination of the heart and lower limb vessels was immediately performed, and the interventional department was consulted. Cardiac ultrasonography suggested that there was no obvious thrombus in the right atrium or right ventricle of the patient. she receive anticoagulant and antiplatelet therapy.Conclusions: Central respiratory failure caused bycerebral stem infarction was considered in the initial stage of the disease. Pulmonary embolism (trunk) may have been the second cause of respiratory failure during diagnosis and treatment. The patient improved obviously after active treatment. Although the patient's condition improved significantly after active treatment, it is worth reflecting that if we had detected the right main pulmonary embolism in a timely manner during the first CTA examination, we could have determined whether the patient could benefit more from thrombolysis of the right main pulmonary artery under interventional therapy. Therefore, in clinical work, we should consider the possible complications ofthe patient while focusing on the most life-threatening primary disease.


2021 ◽  
pp. neurintsurg-2021-017965
Author(s):  
Omar Kass-Hout ◽  
Tibor Becske

Transcirculation thrombectomy through the communicating arteries of the circle of Willis has been previously described as a bailout in cases where direct thrombectomy is not feasible.1–3 Here we present a unique case where a retrograde thrombectomy of the proximal basilar artery was performed using the right posterior communicating artery (PCOM) in a patient with bilateral occlusions of the vertebral arteries, believed to be chronic. This was done using a quadriaxial system with multiple concentric catheters to minimize the ledge effect and achieve smooth and safe transition of the catheters from anterior to posterior circulations. A combination of stent retrieval, aspiration and balloon occlusion guide catheters helped retrieve the thrombus, while minimizing emboli in new territory (ENT). The patient had complete resolution of symptoms. The thrombus is believed to be due to stasis at the vertebrobasilar junction and competing flow, hence, the patient was started on anticoagulation. (video 1)Video 1


2006 ◽  
Vol 21 (6) ◽  
pp. 416-421 ◽  
Author(s):  
Paulo Cesar Silva ◽  
Nelson Jamel ◽  
Ricardo Antonio Refinetti ◽  
Eduardo Ferreira Manso ◽  
Alberto Schanaider

PURPOSE: To verify the development of blood vessels between the greater omentum and the liver in the presence of distinct liver blood intake blockages. METHODS: Two hundred and eighty conventional male Wistar rats were used, divided into 5 groups: control (n=35), laparotomy (n=35); hepatic artery ligature (n=70), ligature of the right-hand branch of the portal vein (n=70); and ligature of both blood vessels (n=70). The last three groups were divided into two subgroups each (n=35), according to the presence or absence of the transposition of the greater omentum onto the right hepatic lobe. The postoperative periods were 1, 3, 7, 15, 30, 60 and 90 days. At the end of each period, the greater omentum and right hepatic lobe were collected for histopathological examination. The presence of blood vessels between the referred tissues was verified by the administration of Indian ink as a marker of vascular lumen. RESULTS: Macroscopic and microscopic observation and the dye marker demonstrated the distribution of blood vessels between the greater omentum and liver tissues. CONCLUSION: The greater omentum was capable of developing blood vessels when fixed to the parenchyma of the liver after the suppression of hepatic blood flow.


Author(s):  
John L. Beggs ◽  
Peter C. Johnson ◽  
Astrid G. Olafsen ◽  
C. Jane Watkins

The blood supply (vasa nervorum) to peripheral nerves is composed of an interconnected dual circulation. The endoneurium of nerve fascicles is maintained by the intrinsic circulation which is composed of microvessels primarily of capillary caliber. Transperineurial arterioles link the intrinsic circulation with the extrinsic arterial supply located in the epineurium. Blood flow in the vasa nervorum is neurogenically influenced (1,2). Although a recent hypothesis proposes that endoneurial blood flow is controlled by the action of autonomic nerve fibers associated with epineurial arterioles (2), our recent studies (3) show that in addition to epineurial arterioles other segments of the vasa nervorum are also innervated. In this study, we examine blood vessels of the endoneurium for possible innervation.


2018 ◽  
Vol 6 (9) ◽  
Author(s):  
DR.MATHEW GEORGE ◽  
DR.LINCY JOSEPH ◽  
MRS.DEEPTHI MATHEW ◽  
ALISHA MARIA SHAJI ◽  
BIJI JOSEPH ◽  
...  

Blood pressure is the force of blood pushing against blood vessel walls as the heart pumps out blood, and high blood pressure, also called hypertension, is an increase in the amount of force that blood places on blood vessels as it moves through the body. Factors that can increase this force include higher blood volume due to extra fluid in the blood and blood vessels that are narrow, stiff, or clogged(1). High blood pressure can damage blood vessels in the kidneys, reducing their ability to work properly. When the force of blood flow is high, blood vessels stretch so blood flows more easily. Eventually, this stretching scars and weakens blood vessels throughout the body, including those in the kidneys.


2016 ◽  
Vol 11 (2) ◽  
pp. 210-217 ◽  
Author(s):  
A.T. Akhmetov ◽  
A.A. Valiev ◽  
A.A. Rakhimov ◽  
S.P. Sametov ◽  
R.R. Habibullina

It is mentioned in the paper that hydrodynamic conditions of a flow in blood vessels with the stenosis are abnormal in relation to the total hemodynamic conditions of blood flow in a vascular system of a human body. A microfluidic device developed with a stepped narrowing for studying of the blood flow at abnormal conditions allowed to reveal blood structure in microchannels simulating the stenosis. Microstructure change is observed during the flow of both native and diluted blood through the narrowing. The study of hemorheological properties allowed us to determine an increasing contribution of the hydraulic resistance of the healthy part of the vessel during the stenosis formation.


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