MODERN CONCEPT OF RENDERING AID TO WOMEN WITH OVARIAN HEMORRHAGES

2021 ◽  
Vol 8 (2) ◽  
pp. 84-89
Author(s):  
Igor Z. Gladchuk ◽  
Oleg Ya. Nazarenko ◽  
Alla G. Volyanska ◽  
Vitalii L. Kozhakov

Aim: Analysis of modern medical care for women with ovarian hemorrhage, determination of the main diagnostic criteria that influence the choice of treatment tactics and further prognosis of the outcome of treatment of ovarian apoplexy. Material and methods: The provision of medical care to 888 women with ovarian apoplexy. Depending on the volume of hemoperitoneum, all patients were divided into three groups.: Group I – 480 (54.0%) women in whom intraabdominal bleeding did not exceed 200 ml; Group II – 283 (31.8%) patients with hemoperitoneum ranged from 200 to 500 ml; Group III – 125 (14.1%) patients with hemoperitoneum volume greater than 500 ml. Results: According to the data of the transvaginal US , a linear dependence was observed between the level of free liquid and the volume of hemoperitoneum (r=0.63, p<0.05). In 792 (89.2%) patients the diagnosis of apoplexy of the ovary and intraperitoneal hemorrhage was made to surgical intervention- on the basis of clinical picture and US data. The most frequently performed hemostatic operation was resection of the ovary – 477 (77.2%) interventions. The average volume of hemoperitoneum discovered in patients with AO, in absence of the adhesive process was (273.5±21.3) ml, whereas in patients with the expressed adhesive process of the small pelvis organs it was (141.4±35.5) ml. The cause of AO was the corpus luteum or cyst of the corpus luteum in more than the half of the cases – 348 (56.3%). Conclusions: The manifestation of the clinical symptoms in apoplexy of the ovaries depends on the volume of intraperitoneal hemorrhage. The application of laparoscopy as a main therapeutic and prophylactic method in AO allows to preserve, and sometimes to restore the reproductive function of a woman and to reduce the rate of the disease relapse development.

Author(s):  
I. Z. Gladchuk ◽  
O. Ya. Nazarenko ◽  
K. M. Shpraidun

Purpose. Analysis of rendering the medical aid to women with apoplexy of the ovary, determination of the basic clinical, laboratory and ultrasonic criteria, which influence the choice of therapeutic tactics, the evaluation of the immediate and long-term results of treatment of ovarian hemorrhages. Materials and methods. There was studied medical aid to 888 women with apoplexy of the ovary from 2012 to 2020. Depending on the volume of hemoperitoneum patients were divided into three groups: І group — 480 (54.0 %) patients whose volume of hemoperitoneum did not exceed 200 ml; ІІ group — 283 (31.8 %) women with intraperitoneal hemorrhage with volume from 200 to 500 ml; ІІІ group — 125 (14.1 %) patients with a volume of hemoperitoneum of more than 500 ml. The group І consisted of ІC group — 270 (30.4 %) women who were given conservative treatment of apoplexy of the ovary (AO), and ІL group — 210 (23.6 %) patients whose main diagnostic and treatment measure was laparoscopic intervention. Results of the study. The average age of the patients was (28.3±5.2). The pelvic pain was the leading clinical symptom in all patients. According to the data of the transvaginal US made in the saggital plane, a linear dependence was observed between the level of free liquid and the volume of hemoperitoneum (r=0.63, p<0.05). In 792 (89.2 %) patients the diagnosis of apoplexy of the ovary and intraperitoneal hemorrhage was made to surgical intervention — on the basis of clinical picture and US data. In the remaining cases — 92 (10.4 %) diagnostic laparoscopy was required for confirming the diagnosis. The average volume of hemoperitoneum discovered in patients with AO, in absence of the adhesive process was (273.5±21.3) ml, whereas in patients with the expressed adhesive process of the small pelvis organs it was (141.4±35.5) ml. The cause of AO was the corpus luteum or cyst of the corpus luteum in more than the half of the cases — 348 (56.3 %). Conclusions. The manifestation of the clinical symptoms in apoplexy of the ovaries depends on the volume of intraperitoneal hemorrhage. The data analysis of transvaginal echography allows to determine quantitatively, with a high degree of accuracy the volume of intraabdominal hemorrhage and the morphological state of the affected ovary. Laparoscopy is not only a “gold standard” in diagnosis and treatment of AO, but also contributes to the prevention of ovarian hemorrhages in future.


Author(s):  
Г.В. ШИРЯЕВ ◽  
Ю.Г. ТУРЛОВА ◽  
Г.С. НИКИТИН

Изучено влияние кормовой добавки в форме индивидуальных болюсов Метраболь на возможность снижения негативного влияния субклинического кетоза (СКК) и результативность искусственного осеменения высокопродуктивных молочных коров в посттранзитный период. Животные были подобраны по принципу условных аналогов и разделены на 3 группы в зависимости от концентрации β-оксимасляной кислоты в их крови. В I группе (n=18) у коров не было СКК, концентрация кислоты составляла <1,0 ммоль/л, во II группе (n=21) у животных зарегистрирован СКК, концентрация кислоты — 1,0…1,4 ммоль/л. С целью поиска решения по снижению негативного влияния СКК на репродуктивные показатели была сформирована III группа коров, переболевших СКК (n=24) с концентрацией β-оксимасляной кислоты в крови 1,0…1,4 ммоль/л, но с использованием болюсов, применяемых для ускоренного восстановления репродуктивной функции коров после отела. Важной составляющей опыта явилось то, что к моменту гормональной синхронизации у коров всех 3 групп фиксировалось отсутствие СКК (снижение β-оксимасляной кислоты до уровня <1,0 ммоль/л). Для синхронизации полового цикла выбрана схема Пресинх-овсинх. Установлено, что гормональная синхронизация животных, перенесших СКК, в сравнении со здоровыми, не позволяет снизить негативное влияние данного нарушения обмена веществ. Во II группе у животных зафиксированы самые низкие репродуктивные показатели (количество использованных доз; индекс осеменения, сервис-период; время от первого до успешного осеменения; результат первичного осеменения; количество животных, осемененных 3 и более раз). В III группе применение болюсов позволило, в сравнении с животными II группы, не только избежать отрицательного воздействия СКК, но и превзойти по изучаемым параметрам животных из I группы. The effect of the feed additive in the form of individual boluses Metrabol on the possibility of reducing the negative effect of subclinical ketosis (CCK) and the effectiveness of artificial insemination of highly productive dairy cows in the post-transit period was studied. The animals were selected according to the principle of conditional analogs and divided into 3 groups depending on the concentration of β-hydroxybutyric acid in their blood. In group I (n=18), the cows did not have SSC, the acid concentration was <1.0 mmol/L, in group II (n=21), SSC was registered in animals — 1.0...1.4 mmol / L. In order to find a solution to reduce the negative effect of CCB on reproductive indices, a group III of cows was formed who had CCB (n = 24) with a concentration of β-hydroxybutyric acid in their blood of 1.0...1.4 mmol/L, but using boluses, used to accelerate the restoration of the reproductive function of cows after calving. An important component of the experiment was that by the time of hormonal synchronization, cows of all 3 groups had no SSC (decrease in β-hydroxybutyric acid to a level of <1.0 mmol/L). To synchronize the sexual cycle, the Pressinh-ovsinh scheme was chosen. It was found that hormonal synchronization of animals that underwent SSC, in comparison with healthy ones, does not allow reducing the negative effect of this metabolic disorder. In group II, animals had the lowest reproductive indices (number of doses used; insemination index, service period; time from first to successful insemination; result of primary insemination; number of animals inseminated 3 or more times). In group III, the use of boluses made it possible, in comparison with animals of group II, not only to avoid the negative effect of SSC, but also to surpass the animals from group I in terms of the studied parameters.


2020 ◽  
Author(s):  
Heng Liu ◽  
Weihua Li ◽  
Lei Zhang ◽  
Bing Liu ◽  
Chaoying Qi ◽  
...  

Abstract Background: The clinical and CT manifestations of COVID-19 pneumonia and non-COVID-19 pneumonia in the same period have not been compared in detail. The purpose of this study is to analyze the clinical and CT manifestations of COVID-19 pneumonia and perform a comparison of those isolated patients for presumed COVID-19 infection and of non-COVID-19 pneumonia in the same period.Methods: 173 patients with pneumonia from January 1, 2020 to March 20, 2020 were retrospectively enrolled and classified into three groups: patients with COVID-19 pneumonia (Group I, N=4), patients in hospital-isolation for presumed COVID-19 pneumonia (Group Ⅱ, N=5), and patients with non-COVID-19 pneumonia (Group III, N=163). Clinical symptoms, laboratory test results and CT imaging features were compared among three groups.Results: Fever and cough were the most common clinical symptoms in the three groups. 30/163 (18.4%) patients were asymptomatic in Group III. Leukopenia, lymphocytopenia, and elevated C-reactive protein was identified in 1 (25%), 1 (25%), and 1 (25%) patient in Group I; 1 (20%), 1 (20%), and 2 (40%) patients in Group II; 10/157 (6.4%), 33/157(21.0%), and 94/136 (69.1%) patients in Group III. Demarcated GGO/mixed GGO, ill-defined GGO/mixed GGO, consolidation, centrilobular nodule, tree-in bud opacity, bilateral involvement, peripheral distribution, posterior part/lower lobe predilection was observed in 3/4 (75%), 2/4 (50%), 4/4 (100%), 2/4 (50%), 0, 3/4 (75%), 3/4 (75%), and 2/4 (50%) patients, respectively in Group I; 1/5 (20%), 5/5 (100%), 4/5 (80%), 4/5 (80%), 3/5 (60%), 4/5 (80%), 2/5 (40%), and 3/5 (60%) patients in Group Ⅱ; 1/163 (0.6%), 87/163 (54.3%), 115/163 (70.6%), 117/163 (71.8%), 95/163 (58.3%), 52/163 (31.9%), 9/163 (5.5%), and 9/163 (5.5%) patients in Group III, respectively.Conclusions: Demarcated GGO and consolidation prefer the diagnosis of COVID-19 pneumonia, whereas ill-defined GGO and consolidation, centrilobular nodule surrounded by GGO, and tree-in-bud opacity are preferred for non-COVID-19 pneumonia. chest CT has potential in early identification of COVID-19 and implementation of isolation for appropriate case.


1997 ◽  
Vol 86 (1) ◽  
pp. 143-150 ◽  
Author(s):  
Luis Renato Mello ◽  
Leonir T. Feltrin ◽  
Paulo T. Fontes Neto ◽  
Fernando A. P. Ferraz

✓ In the search for a new synthetic substitute for the dura mater, the authors conducted a research study using 32 mongrel dogs divided into three groups. Group I animals (21 dogs) underwent a right-sided parietooccipital craniotomy and substitution of two 1-cm pieces of dura mater by two different grafts: one piece of biosynthetic cellulose (50 µ thick) and one fragment of temporal fascia. The animals were observed for 30, 90, or 180 days. Group II animals (five dogs) underwent a somewhat larger craniotomy, removal of a 2-cm piece of dura mater, and lesioning of the cortex made by a thin sharp forceps, which caused bleeding that was controlled by application of a thin film of cellulose (10 µ thick). Duraplasty was performed using a 50-µ-thick cellulose membrane to complete the procedure and the animals were observed over a period of 270 days. Group III animals (six dogs) underwent smaller (1-cm diameter) bilateral parietal craniectomy, which included additional covering of the dura on the left side with 50-µ-thick cellulose and a suture of temporalis muscle. This group was observed for 40, 60, 80, or 120 days. Transient mild clinical symptoms were observed during the early postoperative period. At autopsy, macroscopic examination demonstrated good acceptance of the grafts with few and moderate extradural fibrosis, which caused adherence of the implants to the bone fragment. No adherence to the cortex was observed. Microscopic examination demonstrated absence of graft adherence to the cortical surface even when the cortex was injured. The cellulose was enveloped by two layers of connective tissue, the external layer being thicker than the internal one. Cellulose fibers increased in thickness over time until 30 days and then decreased in thickness until 270 days. This decrease in thickness between 30 to 270 days was statistically significant (p < 0.05). The physical properties of biosynthetic cellulose and the low cellular reaction to its implantation qualify this material as a dural substitute. Additional long-term studies must be undertaken to complete this report.


Neurosurgery ◽  
2004 ◽  
Vol 54 (2) ◽  
pp. 375-380 ◽  
Author(s):  
Ketan R. Bulsara ◽  
Ali R. Zomorodi ◽  
David S. Enterline ◽  
Timothy M. George

Abstract OBJECTIVE To determine whether there are magnetic resonance imaging (MRI) characteristics of fatty fila that are correlated with neurological deficits, especially in the presence of a normal-level conus medullaris. METHODS Lumbosacral MRI scans were reviewed for patients with fatty fila who were treated at Duke University Medical Center during a 5-year period. The patients were divided into three groups. Group I patients (n = 5) had fatty fila that were incidentally detected during evaluations for metastases or infections. Group II patients (n = 16) exhibited isolated low back pain but were in neurologically intact condition. Group III patients (n = 15) exhibited neurological impairments consistent with distal spinal cord dysfunction. Several characteristics were measured on the MRI scans, including the location of the conus medullaris, the filum thickness, and the distance of fat from the conus. These results were assessed for statistically significant correlation with the presence of clinical symptoms. RESULTS The majority of patients in all three groups demonstrated the normal conus position (L2 or above) and thickened fila. The distance of fat from the conus was the only parameter that demonstrated a statistically significant difference among the groups. CONCLUSION The following findings were noted: 1) patients were likely to exhibit neurological deficits at a younger age (&lt;22 yr in Group III versus 47 yr in Groups I and II); 2) a conus level below L2 was associated with neurological deficits (Group III); 3) filum thickness was not correlated with clinical presentation; 4) fat in the filum within 13 mm of the conus medullaris was most predictive of neurological deficits (Group III).


2019 ◽  
Vol 37 (1) ◽  
pp. 112
Author(s):  
Yuriadi Yuriadi ◽  
Ida Tjahajati ◽  
Soedarmanto Indarjulianto ◽  
Irkham Widiyono

ABSTRACT This research aimed at determining the efficacy of duramectin, oxfendazole, piperazine, and pyrantelpamoate against gastrointestinal worms in horses in Yogyakarta Special Region and Central Java. The object of research involved 40 horses diagnosed with gastrointestinal worm infection. Prior to the research, all of the horses were subjected to examination for clinical symptoms and parasitology laboratory checkup for signs of worm eggs in their feces, and they were pronounced positive for experiment animals with at least 150 eggs per gram of feces per horse. The research horses were weighed to determine the dose of worm medication to be used. The research horses are divided into four treatment groups, each group consists of ten horses. Group I was given duramectin with a dose of 0.2 mg/kg of body weight. Group II was given oxfendazole with a dose of 7.5 mg/kg of body weight, Group III was given 125 mg Piperazin treatment per kilogram of body weight and Group IV was given pyrantelpamoate with a dose of 20 mg/kg of body weight. After receiving themedication, the horses were observed to document the progress in terms of clinical symptoms and the amount and type of worm eggs in their feces every three days for four times in a row. The research data results were tabulated and were descriptive-comparatively analyzed.The research result showed varying efficacy level of worm medication for horses. Oxfendazole kills Strongylus and Parascaris worms. Duramectin kills Strongylus worms and reduce some of the Parascaris worms. Piperazineandpyrantelpamoate kills the Strongylus wormsand reduce some of the Parascaris. Keywords: horses, gastrointestinal worms, Duramectin, Oxfendazole, Piperazine, PyrantelPamoate.  


Author(s):  
A.A. SOLOMAKHIN ◽  
O.S. MITYASHOVA ◽  
R.A. RYKOV ◽  
O.V. KONOVALOVA ◽  
I.YU. LEBEDEVA

Недостаток в организме минеральных веществ в послеотельный период может приводить к ухудшению репродуктивной функции коров. В представленной работе изучали изменения содержания кальция, фосфора и магния в крови в динамике в первый триместр лактации у коров-первотелок черно-пестрой породы с разной репродуктивной способностью. Перед отелом (за 2 недели) и после отела (через 1, 3, 5, 7 и 13 недель) у коров брали кровь для определения биохимических показателей. Через 12 мес после отела животных разделили на 3 группы: I группа (сервис-период менее 100 дней), II группа (сервис-период более 100 дней) и III группа (животные, остававшиеся бесплодными более 365 дней). Концентрация кальция в крови коров была минимальной через 1 неделю после отела и возрастала на 10 (P0,05) к 5-й неделе послеродового периода в группе I и к 713-й в группах II и III. У животных III группы содержание фосфора в крови возрастало на 29 (P0,05) между 1-й и 7-й неделями после отела, но не отличалось существенно от данного показателя в двух других группах.Концентрация магния, регулирующего поглощение и резорбцию кальция, была неизменной в крови коров I группы, тогда как у животных II группы она была максимальной между 3-й и 5-й неделями после отела и затем снижалась на 26 (P0,05) к 13-й неделе. В то же время у коров III группы эта концентрация уменьшалась на 17 (P0,05) между 2-й неделей до отела и 3-й после отела. Таким образом, в организме коров с более высокой репродуктивной способностью были эффективнее задействованы адаптационные механизмы, отвечающие за восстановление кальциевого гомеостаза.The lack of minerals in the postpartum period can lead to a deterioration in the reproductive function of cows. In the present work, changes in the blood content of calcium, phosphorus and magnesium in the dynamics of the first trimester of lactation in primiparous black pied cows with different reproductive abilities were studied. Two weeks prepartum and 1, 3, 5, 7 and 13 weeks postpartum, cows were bled to determine biochemical parameters. Twelve months after calving, the animals were divided into 3 groups: with an open daysperiod of less than 100 days (group I), with an open days period of more than 100 days (group II), and animals that remained infertile for more than 365 days (group III). The calcium concentration in the blood of cows was minimal 1 week after calving and increased by 10 (P0.05) by the 5th week of the postpartum period in the group I and by the 713th week in the groups II and III. In animals of the group III, the blood content of phosphorus increased by 29 (P0.05) between the 1st and 7th week after calving, but did not differ significantly from this indicator in the other two groups. The concentration of magnesium, which regulates the absorption and resorption of calcium, was unchanged in the blood of group I cows, whereas in group II animals it was maximum between the 3rd and 5th week after calving and then decreased by 26 (P0.05) by the 13th week. At the same time, in group III cows, this concentration decreased by 17 (P0.05) between the 2nd week before calving and the 3rd week after calving. Thus, in cows with a higher reproductive ability, adaptation mechanisms responsible for the restoration of calcium homeostasis are more effectively involved.


2017 ◽  
pp. 124-126
Author(s):  
I.V. Lakhno ◽  
◽  
A.E. Tkachov ◽  
O.S. Segal ◽  
S.O. Zhdanyuk ◽  
...  

The reason of tumor-like ovarian cysts are functional disorders of the hypothalamic-pituitary-ovarian axis which leads to hyperestrogenocity. Medical preparations containing indole-3-carbinol have an evident antiestrogenic effect. The objective: to study the efficacy of using Mastofemin for the treatment of patients with ovarian cysts. Patients and methods. The study involved 110 patients of reproductive age, 30 of them were healthy and were included in Group I. There were 38 women with follicular cysts in Group II whom 30 мg of ethinylestradiol-containing combined oral contraceptives in cyclic regimen for 3 months were prescribed. There were 42 patients in Group III who were additionally to combined oral contraceptives prescribed Mastofemin for 1 capsule 2 times daily. Results. The presence of combined breast pathology and clinical symptoms associated with hyperestrogenocity has been noted in patients with follicular ovarian cysts. The operative treatment due to the lack of effectiveness of the conservative approach was performed in 21.1% of patients in Group II and 7.1% of women in Group III. There was no recurrence of ovarian cysts during further observation within six months in the main Group of patients receiving Mastofemin. 10.5% of women have the reappeared ovarian retention cysts in the Group II. Conclusion. The use of Mastophemin in addition to combined oral contraceptives for treating women with follicular ovarian cysts contributed to increased compliance and therapeutic efficacy. Key words: ovarian follicular cysts, indole-3-carbinol, Mastofemin.


1981 ◽  
Vol 61 (4) ◽  
pp. 925-934 ◽  
Author(s):  
L. G. GREENBERG ◽  
J. P. MAHONE

The effects of supplemental lighting in stimulating reproductive function in prepuberal boars were studied using littermate boars divided equally into four groups (n = 9). All boars received natural daylight (9.2–12.8 h) until 2 mo of age, followed by artificial light given daily according to the following schedule: boars were exposed to a 15-h photoperiod beginning at the age of 2 (group I); 3 (group II); 4 (group III) or 5 mo (group IV). Libido scores of the four groups increased with age (P < 0.001). Seminal plasma protein (P < 0.01) and zinc concentration (P < 0.05), sperm-rich concentration, sperm-rich volume, total semen volume and total viable sperm increased (P < 0.05) with age in all four groups. The photoperiod treatment had no effect on semen quality on a per ejaculate basis between the groups; 15 h of light per day was not effective in accelerating the onset of puberty when administered from 2, 3, 4 or 5 mo of age onward.


2020 ◽  
Vol 9 (2) ◽  
pp. 611 ◽  
Author(s):  
Brigitte Ohlmann ◽  
Moritz Waldecker ◽  
Michael Leckel ◽  
Wolfgang Bömicke ◽  
Rouven Behnisch ◽  
...  

The aim of this study was to identify correlations between sleep bruxism (SB) and temporomandibular disorders (TMD) as diagnosed by means of the research diagnostic criteria for temporomandibular disorders (RDC/TMD). Sleep bruxism was diagnosed on the basis of I) validated questionnaires, II) clinical symptoms, and III) electromyographic/electrocardiographic data. A total of 110 subjects were included in the study. Fifty-eight patients were identified as bruxers and 52 as nonbruxers. A psychosocial assessment was also performed. An RDC/TMD group-I diagnosis (myofascial pain) was made for 10 out of 58 bruxers, whereas none of the nonbruxers received a diagnosis of this type. No significant differences were found between bruxers and nonbruxers with regard to RDC/TMD group-II (disc displacement) and group-III (arthralgia, arthritis, arthrosis) diagnoses. Somatization was significantly more common among bruxers than nonbruxers. Multivariate logistic regression analysis revealed that somatization was the only factor significantly correlated with the diagnosis of myofascial pain. The results of this study indicate a correlation between myofascial pain, as diagnosed using the RDC/TMD, and somatization. It seems that somatization is a stronger predictor of an RDC/TMD diagnosis of myofascial pain than sleep bruxism is.


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