scholarly journals Study of inert cellulose powder effect on the nasal mucosa

2011 ◽  
Vol 8 (6) ◽  
pp. 53-57
Author(s):  
I B Angotoeva ◽  
E V Sukhovetchenko ◽  
I B Angotoeva ◽  
E V Suhovetchenko

Background. To investigate the efficiency, safety of inert cellulose powder in allergic rhinitis, and influence on mucous tunic of nasal cavity. Materials and methods. Two groups of patients were examined in this research (30 healthy volunteers and 30 patients suffering from allergic rhinitis). The following factors of patients' life and health condition were evaluated during the investigation: quality of life, the condition of mucous tunic, mucociliary clearance rate, the ciliabeat frequency of ciliated cylindrical epithelium, the signs of inflammation in the smears of mucous tunic before and after the treatment with Nazaval and Nazaval Plus. The results. Nazaval and Nazaval Plus improved the quality of life index and reduced the inflammation signs of mucous tunic of nasal cavity examined by rhinoscopy and endoscopy. No ciliotoxic effects of preparations on mucous tunic were established. Conclusion. The inert cellulose powder is a highly effective and safe product for the treatment of allergic rhinitis.

2019 ◽  
Vol 42 (2) ◽  
pp. 21-29
Author(s):  
Malinee Tongdee ◽  
Nichapha Dechapaphapitak ◽  
Thanuchporn Kafaksom ◽  
Umaporn Udomsubpayakul ◽  
Chamard Wongsa ◽  
...  

Background: Chronic rhinitis is a common disease which impacts the quality of life. The symptom of diseases could be controlled after treatment. However, the difference in the quality of life and symptoms after 3 months of treatment is not documented. Objective: To compare the quality of life in chronic rhinitis patients before and at 3 months after treatment. Methods: Prospective study in new cases of chronic rhinitis patients at adult allergy clinic, Ramathibodi Hospital, from August 2017 to March 2018. Assessment of quality of life and nasal symptoms was performed by using the short form 36 health survey questionnaire (SF36) and the rhinoconjunctivitis quality of life questionnaires (RCQ36). Descriptive statistic, t test, and Wilcoxon signed rank test were applied in the data analysis. Results: Of 127 patients, 65.4% were female. Chronic rhinitis was classified as allergic rhinitis, non-allergic rhinitis, and unspecified rhinitis in 72.4%, 18.9%, and 8.7%, respectively. The result of the study showed that there was statistically significant improvement in the quality of life (SF36 and RCQ36 ) and the decrease of nasal and other symptoms score after 3 months of period treatment in chronic rhinitis patients (P < .05). Conclusions: The improvement in the quality of life (SF36 and RCQ36) and the decrease in nasal and other symptoms were documented after 3 months of treatment in chronic rhinitis patients. 


2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
J. T. M. Blauw ◽  
H. A. M. Pastoors ◽  
M. Brusse-Keizer ◽  
R. J. Beuk ◽  
J. J. Kolkman ◽  
...  

Background. Chronic mesenteric ischemia (CMI) is characterized by long-standing abdominal symptoms due to insufficient mesenteric circulation. Data on the effect of revascularisation on quality of life (QoL) for CMI are scarce. This study is the first to evaluate the impact of revascularisation on quality of life. Methods. Seventy-nine patients with CMI or acute-on-chronic mesenteric ischemia (AoCMI) underwent an intervention of one or more mesenteric arteries between January 2010 and July 2012. QoL before and after intervention was measured with the EuroQol-5D. Preintervention questionnaires were of standard care. Postintervention data were obtained by resending a questionnaire to the patients between February and May 2013. To investigate the clinical relevance of our findings, the minimal clinically important difference (MCID) was used. Since there is no established MCID for CMI, we used the literature reference MCID of inflammatory bowel syndrome (IBS) of 0.074. Results. Fifty-five (69.6%) of 79 patients returned their questionnaire and 23 (29.1%) were completely filled out. There was a significant increase of the median EQ-index score from 0.70 to 0.81 (p=0.02) and a significant reduction of symptoms in the domains usual activities (34.4%) and pain/discomfort (32.3%). There was a significant improvement of 17% in overall current health condition (VAS) (p=0.001). The MCID between baseline and postoperative EQ-5D index score was 0.162, indicating a clinically relevant improvement of quality of life after revascularisation. Conclusion. Quality of life of CMI patients is improved after mesenteric artery revascularisation.


Author(s):  
Masoumeh Amirkhani ◽  
Fatemeh Mohebinejad

Introduction: Multiple System Atrophy (MSA) is a degenerative neurogenic disorder characterized by multiple symptoms affecting the movements and autonomic nervous system. It reduces the function of various types of nerve cells in the brain and spinal cord. MSA causes some movement disorders such as dysarthria that is one of the most common symptoms in these patients. The first neurological sign that sometimes progresses is the complete inability to produce speech. This study aimed to evaluate the effect of an intensive voice therapy based on the principles of Lee Silverman Voice Therapy (LSVT) on improving acoustic features, intelligibility, and quality of life index of the patients with MSA. Materials and Methods: The patient was a 57-year-old woman with MSA disorder. Acoustic assessments of voice, intelligibility, and voice handicap index were performed before and after the treatment program according to LSVT principles. Results: Acoustic values such as intensity, frequency, and harmonic to noise ratio increased, and jitter and shimmer parameters decreased. Amount of perception of intelligibility increased. A significant decrease in the scores of the quality of life index related to voice handicap was observed. Conclusion: After treatment by intensive voice therapy, the acoustic assessment revealed improvement in all voice parameters. The perceptual assessment showed improved intelligibility and increased the patient’s quality of life. Intensive voice therapy based on LSVT principles effectively improves the acoustic features, which subsequently cause intelligibility to be more comprehensible. It generally improves verbal communication, which has a positive effect on the patient’s quality of life.


2015 ◽  
Vol 10 (2) ◽  
pp. 157-164 ◽  
Author(s):  
Renáta Jávorné-Erdei ◽  
Péter Takács ◽  
Gergely Fábián

Abstract Improving the health of the population, stopping and changing the disadvantage trends have long been one of the health policy objectives in the regions. Unfortunately in spite of the declared goals Hungary is far away from giving priority to health issues as they are not given proper attention either on individual or societal level. In modern societies local communities play an increasingly important role in the development of quality of life. Their activity, their influence over the power structures become dominant. Quality of life is made up of objective and subjective components. Their important sub-areas are health, financial situation, income situations, housing and social relationship. Quality of life studies are the most frequent health-related research studies, the most remarkable results have been achieved here. Healthrelated quality of life is one of the most important and maybe the most frequently researched dimension of quality of life showing how much health status contributes to the welfare of the individuals. The primary objective of the research studies the improvement of the health status of the population and within it the health status of the individual as well as the reduction of health inequalities can be designated. The improvement of the quality of life can be rationalized as health benefit for the society. Its two main components are the extension of the life expectancy and the increase in numbers of the resulting years. The health of the Hungarian population is said to be unfavourable in international comparison and it can also be stated that it is significantly poorer than it could be expected according to the socio-economic development level


Author(s):  
M. A. Ufimtseva ◽  
N. V. Simonova ◽  
Yu. V. Bochkarev

Introduction. Atrophic postacne scars are a persistent cosmetic defect, cause psychological discomfort, and significantly reduce patients' quality of life. Laser technologies are effectively used for their treatment. The aim of the study was to investigate the quality of life in patients with atrophic post-cancerous scars before and after the use of laser methods of scar correction. Materials and methods. A randomized comparative clinical trial included 120 patients with atrophic postacne scars divided into two comparable groups of 60 patients each. Patients received laser ablation procedures with an Erbium laser (2940 nm). The Dermatological Quality of Life Index (DQLI) questionnaire was used to assess the quality of life before and after the laser procedures. Results. The DICG of patients before treatment ranged from 8 to 17 points and averaged 12.962.05 points. In women the mean value of DICG was 14.221.34 points and was higher compared to men (11.141.45 points) (p0.05). After fractional laser ablation procedures and the procedures of its combination with the treatment of the scar edge with a solid stain, improvement of the DICG scores was observed; intergroup differences were found in self-esteem, in the choice of clothing, in personal and intimate relationships, and in the assessment of daily routine. Discussion. The pre-treatment DICG scores of patients with postacne scars indicate a strong impact of the disease on quality of life. The DICG in women was higher than in men, which may be associated with a greater degree of women's anxiety about the aesthetic condition of the skin and appearance. After treatment, the degree of impact of the disease on patients' quality of life decreased to moderate in both groups. Conclusion. The combined method of treatment contributes to the reduction of DICG compared to fractional ablation procedures, which indicates greater patient satisfaction with the result of these procedures.


2020 ◽  
Author(s):  
Verónica Guillén ◽  
Mireia Esplugues Tormo ◽  
Sara Fonseca-Baeza ◽  
Cristina Botella ◽  
Rosa Baños ◽  
...  

Abstract Background: Studies have suggested that psychotherapy improves the Quality of Life (QoL) of participants with Borderline Personality Disorder (BPD). However, there are no studies on the differential efficacy of treatments on the QoL of participants with BPD. Moreover, the relationship between QoL and resilience has rarely been studied in participants with BPD. Objectives: a) to examine whether people with BPD have worse QoL than the non-clinical population; b) to examine whether there are statistically significant differences between Dialectical Behavioural Therapy (DBT), Systems Training for Emotional Predictability and Problem Solving (STEPPS), or Cognitive Behavioural Therapy-Treatment at Usual (CBT-TAU) in the improvement of QoL; c) to examine whether participants show clinically significant improvements in QoL after treatment; d) to analyse whether resilience is associated with QoL before and after the BPD treatment; e) to analyse whether resilience is a predictor of QoL at pre-treatment and posttreatment. Method: The sample comprised 403 participants (n = 202 participants diagnosed with BPD and n = 201 non-clinical). Participants filled out the Quality of Life Index, Resilience Scale, and Beck Depression Inventory. The clinical participants received one of these possible treatments, DBT, STEPPS, or CBT-TAU. MANOVA and regression analyses were performed. Results: a) participants diagnosed with BPD had statistically significant lower resilience than the non-clinical population; b) all three forms of psychotherapy statistically improved QoL, but there were no statistically significant differences between DBT, STEPPS, and CBT-TAU in the improvement of QoL; c) participants did not show clinically significant improvements in QoL after treatment; d) resilience was associated with QoL before and after treatment; and e) resilience was a predictor of QoL before and after treatment. Conclusion: It is necessary to assess QoL and Resilience in studies on psychotherapy with BPD patients.


Author(s):  
Cabahug, Reagan F. ◽  
Montalan, Gina L. ◽  
Yape, Irma Marie P. ◽  
Laurenciana, Maria Cristina M.

Objective: To determine the efficacy (sensitivity, specificity, and accuracy) of the VeinesQol/Sym with metric statements fewer than the EQ5D in detecting the quality of life of patients with Chronic Venous Disease (CVD) before and after treatment. Methods: This is a descriptive-comparative design in collecting the necessary data to arrive at conclusions that respond to the specific questions of the study in 2 private hospitals. The responses gathered from patients through EQ5D and VeinesQol/Sym, before and after they received treatment were utilized in describing and comparing the efficacy of the health questionnaires.  Data were further subjected to a comparative analysis to elaborate the efficacy of the VeinesQol/Sym.  Results: A total of 114 CVD patients completed the study after the exclusion of 13 patients due to failure to follow up after eight weeks of treatment. The study showed that VeinesQol/Sym and EQ5D has similar efficacy in determining quality of life of CVD patients. However, VeinesQol/Sym  has higher accuracy (84.96% vs 76.99%), higher sensitivity (87.85% vs 83.87%), detects greater level of impairment in mobility, anxiety/depression, pain and discomfort, disruptions in usual activity and lower quality of current state of health condition than EQ5D Conclusion: With the responses to the metric statements of the indicators of quality life in both VeinesQol/Sym and EQ5D, VeinesQol/Sym was found to have a greater efficacy in establishing the accurate status of quality of life of patients with CVD than the EQ5D.


Medicina ◽  
2008 ◽  
Vol 44 (4) ◽  
pp. 296 ◽  
Author(s):  
Tomas Balsevičius ◽  
Virgilijus Uloza ◽  
Raimundas Sakalauskas ◽  
Skaidrius Miliauskas ◽  
Regina Rėklaitienė ◽  
...  

Objective. To arrange and test for its psychometric properties Lithuanian version of Sleep Apnea Quality of Life Index and assess quality of life among snoring and obstructive sleep apnea patients before and after the treatment. Material and methods. Cross-cultural adaptation of Lithuanian version of Calgary Sleep Apnea Quality of Life Index was accomplished according to generally accepted methodology. In total, 36 (29 males and 7 females) patients (mean age, 41.1±9.7 years) suffering from socially disturbing snoring and obstructive sleep apnea were included into the study. All patients underwent complete full-night polysomnography (mean apnea/hypopnea index, 12.7±11.2) and were treated with two sessions of radiofrequency tissue ablation at the palatal and tong base (if it was necessary) levels. Lithuanian version of the Calgary Sleep Apnea Quality of Life Index was presented before the treatment with radiofrequency tissue ablation and in the period of 2 to 3 months after the treatment. Thirty-five patients repeated the same questionnaire after three weeks to assess the reliability of scores. Results. The Cronbach’s α coefficients of internal reliability were above the standard (0.7 for groups) in all subdomains and domains. Test-retest correlation coefficients for each domain (ranged from 0.92 to 0.94) were statistically significant (P<0.0001). Lithuanian version of the questionnaire was found to be responsive to clinical change. A statistically significant difference in the mean Sleep Apnea Quality of Life Index scores in the study group patients before and after the surgery was found in all daily functioning subdomains and social interactions domains. Conclusions. Overall, the results of the present pilot study demonstrate that the Lithuanian version of Sleep Apnea Quality of Life Index is applicable for clinical purposes.


2021 ◽  
Vol 10 (17) ◽  
pp. 3845
Author(s):  
Sol Marcos ◽  
Luisa María Botella ◽  
Virginia Albiñana ◽  
Agustina Arbia ◽  
Anna María de Rosales

Epistaxis is the most prevalent clinical symptom in Hereditary Haemorrhagic Telangiectasia (HHT), causing anaemia and decreasing the quality of life (QOL). Since 2013, in Hospital Universitario Fundación Alcorcón, more than 150 HHT patients have been treated by nose sclerotherapy on demand. This study shows the results of 105 patients treated with sclerotherapy between 2017 and 2019. HHT-ESS (epistaxis severity score) was used to measure the severity and frequency of epistaxis. QOL was determined before and after treatment by EuroQol-5D (EQ-5D) and the visual analogue scale (VAS) on the health condition. According to HHT-ESS before treatment, 22 patients presented mild, 35 moderate, and 47 severe epistaxes. Sclerotherapy significantly decreased the frequency and severity of epistaxis, with a significant drop of HHT-ESS in 4.6 points, from 6.23 ± 2.3 to 1.64 ± 1.6. Furthermore, the QOL significantly improved, the EQ-5D scale raised from 0.7 ± 0.26 pre- to 0.92 ± 0.16 post-treatment (p < 0.05). Additionally, VAS mean value showed a significant increase from 4.38 ± 2.4 to 8.35 ± 1.2. The QOL improvement was correlated with the ESS decrease. In conclusion, this study shows that on-demand sclerotherapy at the office significantly reduces HHT epistaxis as well as improved the patients’ QOL.


2016 ◽  
Vol 13 (2) ◽  
pp. 36-43
Author(s):  
T G Fedoskova ◽  
V M Svistushkin ◽  
E A Shevchik

Rhinitis (allergic, vasomotor and others) is common inflammatory disease of the nasal cavity. Clinical manifestations of chronic rhinitis, such as nasal obstruction, discharge from the nasal cavity, significantly reduce the quality of life of the patients. Efficacy of modern antihistamine - azelastin in the treatment of seasonal and perennial allergic rhinitis is presented in the article.


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