scholarly journals REMOTE RESULTS OF SUBLINGUAL ALLERGENSPECIFICIMMUNOTHERAPY AT POLLINOSIS PATIENTS - FIVE YEARS'RESEARCH

2011 ◽  
Vol 8 (3) ◽  
pp. 31-36
Author(s):  
Marina Valentinovna Manzhos ◽  
E S Fedenko ◽  
M A Myagkova ◽  
G A Keropyan ◽  
S A Shkadov ◽  
...  

Background. The purpose of the work was to investigate remote and preventive results of sublingual allergenspecific immunotherapy (SLiT) at pollinosis patients. Methods. 25 patients at the age from 19 till 50 years old with an allergic rhinitis and asthma (35%) sensitized to artemisia were under the supervision. SLiT was administered in the period since September 2003 till May 2006 with pollen allergen («Sevapharma», Czech Republik). The average total dose of the allergen per one patient at the end of the third year was 189999 PNU. Clinical efficiency was estimated annually and in 30 months after discontinuation of SLiT. Frequency and intensity of symptoms during the pollen season, requirement for medicines, FEV1 parameters and results of prick tests were considered. Results. good and excellent results after three courses of immunotherapy demonstrated 23 patients (92%), satisfactory - 2 patients (8%). The results were remained at 22 patients (88%) within the next 30 months. at 3 patients (12%) increase of rhinoconjunctivitis symptoms was noted, and 3 (12%) showed expansion of a sensibilisation spectrum. Further increase of intensity and frequency of asthma symptoms, decrease in indicators FEV1 was not registered. Conclusion. SLiT is a highly effective method of treatment for patients with seasonal rhinitis and leads to the clinical results remaining more than 2 years at the majority of patients.

Allergy ◽  
1999 ◽  
Vol 54 (8) ◽  
pp. 804-810 ◽  
Author(s):  
Ml Kowalski ◽  
A Dietrich-miłobędzki ◽  
B Majkowska-wojciechowska ◽  
M Jarzębska

2011 ◽  
Vol 9 (3) ◽  
pp. 285-288 ◽  
Author(s):  
A. Kasperska-Zajac ◽  
E. Czecior ◽  
A. Grzanka ◽  
E. Machura ◽  
M. Misiolek

2020 ◽  
Vol 7 (1) ◽  
pp. e000658
Author(s):  
Blanca Estela Del-Río-Navarro ◽  
Arturo Berber ◽  
Nayely Reyes-Noriega ◽  
Elsy Maureen Navarrete-Rodríguez ◽  
Roberto García-Almaraz ◽  
...  

BackgroundGlobal Asthma Network (GAN) was established in 2012 as a development to the International Study of Asthma and Allergies in Childhood to improve asthma care globally.ObjectiveTo survey asthma, allergic rhinitis and atopic dermatitis in primary and secondary school children and to investigate and evaluate its prevalence, severity, management and risk factors in Mexico.MethodsGAN Phase I is a cross-sectional, multicentre survey carried out in 15 centres corresponding to 14 Mexican cities throughout 2016–2019 using the validated Spanish language version of the GAN Phase I questionnaires. The questionnaires were completed by parents of 6–7-year-old primary school pupils (school children) and by 13–14-year-old adolescents.ResultsA total of 35 780 school children and 41 399 adolescents participated. Wheezing ever prevalence was 26.2% (95% CI 25.8% to 26.7%) in school children and 23.9% (95% CI 23.4% to 24.3%) in adolescents. The corresponding frequencies for current wheeze were 10.2% (95% CI 9.9% to 10.5%) and 11.6% (95% CI 11.2% to 11.9%). In school children, the risk factors for current wheeze were rhinitis (OR 4.484; 95% CI 3.915% to 5.134%) and rash symptoms (OR 1.735; 95% CI 1.461% to 2.059%). For adolescents, rhinitis symptoms (OR 3.492; 95% CI 3.188% to 3.825%) and allergic rhinitis diagnosis (OR 2.144; 95% CI 1.787% to 2.572%) were the most significant. For both groups, there was a negative relation with centres’ sea level altitude higher than 1500 m above mean sea level (p<0.005).ConclusionsThe most important risk factors for asthma symptoms in both age groups were the presence of rhinitis and rash symptoms or diagnosis. On the other hand, sea level altitude higher than 1500 metres was a protective factor.


2019 ◽  
Vol 57 (3) ◽  
pp. 286-289
Author(s):  
Masako To ◽  
Ryuta Tsuzuki ◽  
Otohiro Katsube ◽  
Satoshi Yamawaki ◽  
Seiko Soeda ◽  
...  

1999 ◽  
Vol 13 (2) ◽  
pp. 301-306 ◽  
Author(s):  
A.h. Henriksen ◽  
M. Sue-Chu ◽  
T. Lingaas Holmen ◽  
A. Langhammer ◽  
L. Bjermer

2003 ◽  
Vol 130 (4) ◽  
pp. 307-313 ◽  
Author(s):  
Carlos E. Baena-Cagnani ◽  
William E. Berger ◽  
Lawrence M. DuBuske ◽  
Sandra E. Gurné ◽  
Paul Stryszak ◽  
...  

Author(s):  
Aamir Magzoub ◽  
Omer Musa ◽  
Asma Elsony ◽  
Ghada Elmahi ◽  
Azza Alawad ◽  
...  

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